[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584583":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":49,"collaborators":52,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Prospective community sample",null,"Community sample of 200 younger adults aged 18-30 years who have used cannabis in the past 30 days, report use frequency of ≥1x\u002Fweek, and have a positive test for urinary 11-nor-9-carboxy-delta-9-tetrocannabinol (THC-COOH) at baseline",[13],"Other: Biologic testing for THC",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Biologic testing for THC","Participants will be asked to complete at-home urine test(s) and a series of oral fluid tests.",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Lydia A Shrier, MD, MPH","CONTACT","(617) 355-8306","lydia.shrier@childrens.harvard.edu",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Madison M O'Connell, MPH","617-919-6964","softa@childrens.harvard.edu",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-71.05977,42.35843,{"lat":41,"lon":40},[44,47],{"name":45,"role":22,"phone":46,"phoneExt":10,"email":24},"Lydia A. Shrier, MD, MPH","617-355-8306",{"name":45,"role":48,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":48,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Lydia Shrier","Research Director",[53],{"name":54,"class":55},"National Institute on Drug Abuse (NIDA)","NIH","100584583","study-of-an-oral-fluid-testing-approach-100584583",false,"NCT06891235","Study of an Oral Fluid Testing Approach","Oral Fluid Testing to Assess Cannabis Non-Use in Remote Clinical Trials","SOFTA","Inclusion Criteria:\n\n* Age 18 to 30 years\n* Cannabis use on \\>=1x\u002Fweek in the past 30 days\n* Ownership of a portable device that is capable of videoconference and videorecording (i.e., smartphone, tablet computer, or laptop computer)\n* Ability to read and speak English\n* Availability for duration of the study (3-4 weeks).\n* To proceed to oral fluid testing, positive result for urinary TCH-COOH\n\nExclusion Criteria:\n\n• Inability\u002Funwillingness to provide contact information","ALL","18 Years","30 Years",{"count":68,"type":69},200,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to identify and evaluate oral fluid testing as a biologic measure of cannabis use days that can be assessed remotely. The researchers will conduct this fully virtual study among a community sample of 200 individuals aged 18-30 years who have used cannabis at least 1 time per week on average in the past 30 days. Participants will complete oral fluid (saliva) tests, urine tests, and Timeline Follow-back interviews (self-report) that indicate their recent cannabis use (delta-9-THC). Participants will present for 3 virtual study visits across \\~3-4 weeks and be asked to complete activities in between: Study Visit 1 (Day 0; informed consent, baseline survey, TLFB interview), Study Visit 2 (\\~Day 7; TLFB interview, urine testing), 6 days of at-home videorecorded oral fluid testing, Study Visit 3 (\\~Day 21; TLFB interview, urine test, oral fluid test, survey, interview).",[73,74,75],"Cannabis Use","Cannabis Intoxication","Cannabis Use Disorder",[77,78,79],"cannabis use","young adult","oral fluid testing","2026-06-27",{"date":82,"type":83},"2026-07-01","ACTUAL",{"date":85,"type":83},"2025-10-27",{"date":87,"type":69},"2027-05",{"name":5,"class":6},1]