[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100293499":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":27,"centralContacts":31,"locations":39,"responsibleParty":81,"collaborators":84,"id":89,"slug":90,"hasResults":91,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":26,"eligibilityCriteria":95,"healthyVolunteers":96,"sex":97,"minAge":98,"maxAge":99,"enrollmentInfo":100,"targetDuration":26,"studyType":103,"phases":104,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":42,"whyStopped":26,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"University of California, San Diego","OTHER",[8,13,17],{"label":9,"type":6,"description":10,"interventionNames":11},"Anorexia nervosa I","Anorexia nervosa with BMI \\\u003C=17.5 kg\u002Fm² or BMI \\>17.5 kg\u002Fm² with regular binge-purge episodes",[12],"Other: A breakfast sandwich",{"label":14,"type":6,"description":15,"interventionNames":16},"Anorexia nervosa II","Anorexia nervosa with BMI \\> 18.5 kg\u002Fm² for at least 12 months.",[12],{"label":18,"type":6,"description":19,"interventionNames":20},"Controls","Healthy control women",[12],[22],{"type":6,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"A breakfast sandwich","A meat-based breakfast sandwich",[9,14,18],null,[28],{"name":29,"affiliation":5,"role":30},"Pei-an (Betty) Shih, MPM, PhD","PRINCIPAL_INVESTIGATOR",[32,36],{"name":29,"role":33,"phone":34,"phoneExt":26,"email":35},"CONTACT","(858) 534-0828","eatingdisorderresearch@ucsd.edu",{"name":37,"role":33,"phone":26,"phoneExt":26,"email":38},"Nhien Nguyen, MS","n7nguyen@ucsd.edu",[40,60],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"UC San Diego Altman Clinical and Translational Research Institute","RECRUITING","La Jolla","California","92037","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-117.2742,32.84727,{"lat":52,"lon":51},[55,58],{"name":56,"role":33,"phone":57,"phoneExt":26,"email":35},"P. Betty Shih, MPM, PhD","858-534-0828",{"name":59,"role":30,"phone":26,"phoneExt":26,"email":26},"Pei-an Betty Shih, MPM, PhD",{"facility":61,"status":42,"city":62,"state":63,"zip":26,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"Program for Eating Disorders, Toronto General Hospital","Toronto","Ontario","Canada","CA",{"type":49,"coordinates":67},[68,69],-79.39864,43.70643,{"lat":69,"lon":68},[72,76,78,79],{"name":73,"role":33,"phone":74,"phoneExt":26,"email":75},"D. Blake Woodside","416-340-4445","pbshih@ucsd.edu",{"name":77,"role":33,"phone":74,"phoneExt":26,"email":75},"D. Blake Woodside, MD FRCPC",{"name":77,"role":30,"phone":26,"phoneExt":26,"email":26},{"name":80,"role":30,"phone":26,"phoneExt":26,"email":26},"Pei-an (Betty) Shih, PhD",{"type":30,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Pei-an (Betty) Shih","Associate Professor",[85,87],{"name":86,"class":6},"University of Toronto",{"name":88,"class":6},"University of California, Davis","100293499","study-of-food-aversion-in-patients-with-anorexia-nervosa-100293499",false,"NCT03100656","Study of Food Aversion in Patients With Anorexia Nervosa","Solving EPHX2 and Polyunsaturated Fatty Acid Interactions in Anorexia Nervosa","Inclusion Criteria:\n\n* Ill AN subjects will meet current Diagnostic and Statistical Manual of Mental Disorders (DSM V) diagnosis of AN, body mass index (BMI) between 11 kg\u002Fm² and 17.5 kg\u002Fm², or BMI \\> 17.5 kg\u002Fm² with active eating disorder symptoms.\n* Recovered AN must meet the following criteria at time of study entry: 1) Current or past DSM V diagnosis of AN; 2) BMI between 18.5 kg\u002Fm2 and 30 kg\u002Fm2; 3) Having maintained a BMI of \\>18.5 for at least one year.\n* Control must be healthy adolescent or woman negative on our screen for AN, other Axis I psychiatric illnesses, and having maintained a BMI of between 18.5-30 kg\u002Fm² since the age of 18.\n\nExclusion Criteria:\n\n* Exclusion criteria for AN and control subjects include: Organic brain syndrome, schizophrenia and schizoaffective disorder, untreated thyroid disease, renal disease, hepatic disease, and the regular use of fish-oil containing supplements within the last three months of the study. All pregnant and lactating individuals will be excluded.",true,"FEMALE","18 Years","55 Years",{"count":101,"type":102},300,"ESTIMATED","INTERVENTIONAL",[105],"NA","This study uses a meal-challenge protocol to assess if patients with anorexia nervosa show a differential metabolism in response to food in comparison to healthy controls. This study determines how heritable and biochemical factors influence food metabolism in anorexia nervosa in order to develop more effective treatment strategies.",[108],"Anorexia Nervosa",[110,111,112,113,114],"psychopathology","treatment","epoxide hydrolases","polyunsaturated fatty acids","eicosanoids","2026-03-28",{"date":117,"type":118},"2026-03-31","ACTUAL",{"date":120,"type":118},"2016-11-10",{"date":122,"type":102},"2027-12-31",{"name":5,"class":6},2]