[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100456887":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":19,"responsibleParty":77,"collaborators":7,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":81,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":7,"studyType":93,"phases":7,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":22,"whyStopped":7,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Children's Hospital Medical Center, Cincinnati","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Paneez Khoury, MD","National Institutes of Health (NIH)","STUDY_CHAIR",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Regina Yearout","CONTACT","(513) 517-2108","Regina.Yearout@cchmc.org",[20,42,61],{"facility":21,"status":22,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Northwestern University","RECRUITING","Chicago","Illinois","60208","United States","US",{"type":29,"coordinates":30},"Point",[31,32],-87.65005,41.85003,{"lat":32,"lon":31},[35,39],{"name":36,"role":16,"phone":37,"phoneExt":7,"email":38},"Rose Arrieta","312-695-5878","rarrieta@northwestern.edu",{"name":40,"role":41,"phone":7,"phoneExt":7,"email":7},"Nirmala Gonsalves, MD","PRINCIPAL_INVESTIGATOR",{"facility":43,"status":22,"city":44,"state":45,"zip":46,"country":26,"countryCode":27,"cosmosGeoPoint":47,"geoPoint":51,"contacts":52},"The National Institutes of Health","Bethesda","Maryland","20892",{"type":29,"coordinates":48},[49,50],-77.10026,38.98067,{"lat":50,"lon":49},[53,57,60],{"name":54,"role":16,"phone":55,"phoneExt":7,"email":56},"Perla Adames-Castillo, RN","301-402-5969","perla.adamescastillo@nih.gov",{"name":58,"role":16,"phone":7,"phoneExt":7,"email":59},"Megan Koch","megan.koch@nih.gov",{"name":10,"role":41,"phone":7,"phoneExt":7,"email":7},{"facility":62,"status":22,"city":63,"state":64,"zip":65,"country":26,"countryCode":27,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"University of Utah","Salt Lake City","Utah","84112",{"type":29,"coordinates":67},[68,69],-111.89105,40.76078,{"lat":69,"lon":68},[72,75],{"name":73,"role":16,"phone":7,"phoneExt":7,"email":74},"Amy Nichols","Amy.Nichols@hsc.utah.edu",{"name":76,"role":41,"phone":7,"phoneExt":7,"email":7},"Kathryn Peterson, MD",{"type":78,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100456887","study-of-gastric-motility-in-eosinophilic-gastritis-100456887",false,"NCT05229432","Study of Gastric Motility in Eosinophilic Gastritis","Pilot Assessment to Find Evidence of Gastric Motility Abnormalities in Eosinophilic Gastric Disorders","OAT-FEED","Inclusion Criteria:\n\n* Eosinophilic gastritis (EG) defined as at least one endoscopy with histopathologic evidence of ≥ 30 eosinophils in 5 or more high powered fields (hpf's) with associated symptoms of EG.\n* Patient reported symptoms starting at least one year or more prior to screening consistent with a diagnosis of EG: nausea, vomiting, early satiety, abdominal pain\u002Fbloating, regurgitation, diarrhea.\n* Symptoms suggestive of a possible gastric motility disorder during the 60 days prior to screening including: nausea, vomiting, early satiety, post-prandial feeling of fullness or bloating.\n* Tolerance and willingness to consume the oatmeal meal in this study.\n\nExclusion Criteria:\n\n* Diagnosis of eosinophilic enteritis.\n* Inflammatory bowel disease (e.g., Crohn's disease or ulcerative colitis).\n* Known disorders associated with eosinophilic gastrointestinal (GI) diseases (e.g., D 816 V Kit+ systemic mastocytosis, Marfan syndrome or Loey's Dietz Syndrome).\n* Known inflammatory or autoimmune disorders associated with gastric dysmotility such as systemic sclerosis, lupus or eosinophilic fasciitis.\n* Uncontrolled diabetes or known diabetic complications of gastroparesis, neuropathy or nephropathy.\n* Taking opioid agents in the 2 weeks prior to screening and throughout the study.\n* History of strictures in the small bowel or stomach (e.g., pyloric stenosis) or gastric surgeries or procedures such as pyloromyotomy, pyloric dilation, pyloric resection, vagotomy, bariatric surgery or post-Nissen fundoplication or antrectomy with Billroth I, Billroth II or Roux-en-Y gastrojejunostomy.\n* Past or current medical problems or findings such as: advanced liver disease (Child's B or C), acute or chronic renal disease (serum creatinine \\> 3 mg\u002FdL), neurologic disease (e.g., dysautonomia), achalasia and adrenal insufficiency.","ALL","18 Years","59 Years",{"count":91,"type":92},30,"ESTIMATED","OBSERVATIONAL","Purpose:\n\nThe study is a cross-sectional observational study designed to determine if eosinophilic gastritis (EG) results in gastric motility impairment.\n\nHypothesis:\n\nGastric dysfunction occurs in the natural history of EG but is underdiagnosed due, in part, to contraindications to the use of the standard meals used in gastric emptying studies.",[96,97,98],"Eosinophilic Gastritis","Gastroparesis","Gastric Motility Disorder",[100,101,102,103,104,105,106,107,108,109,110,111],"Gastritis","Eosinophilic Gastrointestinal Disorders","Gastric Dysfunction","Gastric Dysmotility","Eosinophils","Eosinophilia","Eosinophilic Disorders","Digestive System Diseases","Immune System Diseases","Stomach Diseases","Gastric Emptying Scintigraphy","Endoscopy","2026-03-26",{"date":114,"type":115},"2026-03-31","ACTUAL",{"date":117,"type":115},"2023-01-25",{"date":119,"type":92},"2026-12-01",{"name":5,"class":6},3]