[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601721":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":20,"collaborators":11,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":26,"acronym":11,"eligibilityCriteria":27,"healthyVolunteers":28,"sex":29,"minAge":30,"maxAge":31,"enrollmentInfo":32,"targetDuration":11,"studyType":35,"phases":36,"briefSummary":38,"conditions":39,"keywords":11,"overallStatus":43,"whyStopped":11,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":11},{"fullName":5,"class":6},"Xijing Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Safety assessment","EXPERIMENTAL",null,[13],"Diagnostic Test: 68Ga-ACC-DE\u002F68Ga-FASN-DE\u002F68Ga-ACLY-DE PET\u002FCT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DIAGNOSTIC_TEST","68Ga-ACC-DE\u002F68Ga-FASN-DE\u002F68Ga-ACLY-DE PET\u002FCT","Recruit 15 healthy adult volunteers, divided into three groups, to undergo dynamic PET\u002FCT (1 hour) and static PET\u002FCT (2 hours and 3 hours) imaging with 68Ga-ACC-DE, 68Ga-FASN-DE, or 68Ga-ACLY-DE, respectively, to assess safety, biodistribution, and radiation dosimetry, laying the foundation for subsequent studies.",[9],{"type":21,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100601721","study-of-melanoma-resistant-pet-monitoring-based-on-key-rate-limiting-enzymes-for-fatty-acid-metabolism-in-healthy-volunteers-100601721",false,"NCT07114172","Study of Melanoma-Resistant PET Monitoring Based on Key Rate-limiting Enzymes for Fatty Acid Metabolism in Healthy Volunteers","Inclusion Criteria:\n\n* Age: 18 to 65 years old (including the boundary values); Gender: Male or female; Weight: Male weight ≥ 50 kg, female weight ≥ 45 kg, and body mass index (BMI = weight (kg) \u002F height² (m²)) within the range of 18.0 to 28.0 kg\u002Fm² (including boundary values); Participants must fully understand and voluntarily participate in this experiment and sign an informed consent form.\n\nExclusion Criteria:\n\n* Individuals who cannot tolerate intravenous administration (e.g., those with a history of fainting from needles or blood); Individuals with alcohol allergies; Pregnant or breastfeeding women; Individuals with severe diseases of the heart, kidneys, lungs, blood vessels, nervous system, or mental health, immune deficiency diseases, or hepatitis\u002Fcirrhosis; Individuals whom the investigator deems unsuitable for or unable to complete PET or other imaging examinations for special reasons; Other circumstances deemed by the investigator to be unsuitable for participation in this study.",true,"ALL","18 Years","65 Years",{"count":33,"type":34},15,"ESTIMATED","INTERVENTIONAL",[37],"NA","This is a small-sample safety study involving 15 healthy volunteers who were divided into groups and underwent 68Ga-ACC-DE, 68Ga-FASN-DE, and 68Ga-ACLY-DE PET\u002FCT imaging for safety, biodistribution, and radiation dosimetry assessments, laying the foundation for subsequent studies on the efficacy of resistance monitoring in melanoma targeted therapy.",[40,41,42],"Melanoma (Skin Cancer)","Health Volunteers","PET \u002F CT","NOT_YET_RECRUITING","2025-08-08",{"date":46,"type":47},"2025-08-11","ACTUAL",{"date":49,"type":34},"2025-08-15",{"date":51,"type":34},"2025-10-15",{"name":5,"class":6}]