[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505271":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":33,"responsibleParty":49,"collaborators":51,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University Hospital, Tours","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"LUPUS PATIENTS",null,"Three extra tubes of blood will be taken at each consultation or inpatient visit when routine blood samples are taken as part of lupus monitoring.",[13],"Biological: Blood sample",[15],{"type":16,"name":17,"description":11,"armGroupLabels":18,"otherNames":10},"BIOLOGICAL","Blood sample",[9],[20],{"name":21,"affiliation":22,"role":23},"Yanis RAMDANI","CHRU de Tours","PRINCIPAL_INVESTIGATOR",[25,30],{"name":21,"role":26,"phone":27,"phoneExt":28,"email":29},"CONTACT","0234378919","+33","yanis.ramdani@univ-tours.fr",{"name":31,"role":26,"phone":10,"phoneExt":10,"email":32},"Valérie GOUILLEUX-GRUART","valerie.gouilleux@univ-tours.fr",[34],{"facility":35,"status":36,"city":37,"state":10,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"University Hospital","RECRUITING","Tours","37044","France","FR",{"type":42,"coordinates":43},"Point",[44,45],0.70398,47.39484,{"lat":45,"lon":44},[48],{"name":21,"role":26,"phone":27,"phoneExt":28,"email":29},{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[52],{"name":53,"class":54},"Research Center for Respiratory Diseases, Inserm U1100","UNKNOWN","100505271","study-of-neonatal-igg-fc-receptor-expression-in-natural-killer-t-cells-expressing-an-invariant-t-receptor--implication-in-the-pathophysiology-of-systemic-lupus-100505271",false,"NCT05859191","Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus","Study of Neonatal Immunoglobulin G (IgG) Fc Receptor (FcRn) Expression in Natural Killer T Cells Expressing an Invariant T Receptor (iNKT): Implication in the Pathophysiology of Systemic Lupus","FiNKLUPUS","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Diagnosis of definite systemic lupus which may be associated with secondary antiphospholipid syndrome and\u002For secondary Gougerot-Sjögren's\n* Lupus patient, newly diagnosed or known, untreated or in relapse\n* Lupus patient considered stable by the treating practitioner\n* Requiring blood sampling for follow-up\n\nExclusion Criteria:\n\n* Main autoimmune disease other than lupus\n* Patient under legal protection, guardianship or curators\n* Opposition to data processing",true,"ALL","18 Years",{"count":67,"type":68},50,"ESTIMATED","OBSERVATIONAL","This study evaluates the variation of expression of the neonatal Fc receptor (FcRn) in Natural Killer T Cells Expressing an Invariant T Receptor (iNKT) and monocytes along with the surface expression of Fc gamma type II receptor (RII) and RIII in active or newly diagnosed lupus patients compared to inactive lupus patients.",[72,73],"Systemic Lupus Erythematosus","Physiopathology",[75],"lupus","2026-04-29",{"date":78,"type":79},"2026-04-30","ACTUAL",{"date":81,"type":79},"2023-07-21",{"date":83,"type":68},"2030-07",{"name":5,"class":6},1]