[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100491037":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":44,"responsibleParty":59,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":25,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":25,"enrollmentInfo":71,"targetDuration":25,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":25,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"tDCS Treatment A (Low Amplitude)","EXPERIMENTAL","Subjects with focal epilepsy that is not well-controlled on anti-seizure medications will receive 2 different treatments periods, each lasting 2 months, of transcranial direct current stimulation (tDCS). The initial treatment stimulation will be completed during the first 2-months.",[13],"Device: ActivaDose II 0.1 mA transcranial direct current stimulation (tDCS)",{"label":15,"type":10,"description":16,"interventionNames":17},"tDCS Treatment B (High Amplitude)","Subjects with focal epilepsy that is not well-controlled on anti-seizure medications will receive 2 different treatments periods, each lasting 2 months, of transcranial direct current stimulation (tDCS). The last treatment stimulation will be completed during the following 2-months.",[18],"Device: ActivaDose II 2.0 mA transcranial direct current stimulation (tDCS)",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","ActivaDose II 0.1 mA transcranial direct current stimulation (tDCS)","Stimulation setting 0.1 mA daily for a 2-month period. Each daily treatment will last for approximately 30 minutes.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"ActivaDose II 2.0 mA transcranial direct current stimulation (tDCS)","Stimulation setting 2.0 mA daily for a 2-month period. A Each daily treatment will last for approximately 30 minutes.",[15],[31],{"name":32,"affiliation":5,"role":33},"Brian Lundstrom, MD, PhD","PRINCIPAL_INVESTIGATOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Precylla Ruiz","CONTACT","507-538-6606","ruiz.precylla@mayo.edu",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Izzie Meunier","507-538-6337","meunier.isabelle@mayo.edu",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":25},"Mayo Clinic Minnesota","RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-92.4699,44.02163,{"lat":57,"lon":56},{"type":33,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Brian N. Lundstrom","Principal Investigator","100491037","study-of-transcranial-direct-current-stimulation-to-treat-epilepsy-100491037",false,"NCT05673915","Study of Transcranial Direct Current Stimulation to Treat Epilepsy","Pilot Study of Transcranial Direct Current Stimulation (tDCS) to Treat Epilepsy","Inclusion Criteria\n\n* Clinical diagnosis of generalized onset or focal epilepsy or sleep-related epileptic encephalopathy.\n* Estimated to have at least 2 countable seizures per month or spike-wave index ≥50%.\n* Has not had control with at least 2 anti-seizure medicines.\n* Able to maintain a constant medication for duration of the study (rescue meds allowed).\n* Subject or legally authorized representative is able to understand consent and keep a seizure diary in English.\n\nExclusion Criteria:\n\n* A disease likely to progress over course of the study.\n* Psychogenic non-epileptic seizures.\n* Suicide attempt or psychiatric hospitalization past 2 years.\n* A skin condition interfering with scalp electrodes or allergy to silver.\n* Women will verify not pregnant, and if applicable, have a serum pregnancy test.\n* Implanted devices (e.g. pacemakers)-except VNS, which is allowed.","ALL","6 Years",{"count":72,"type":73},30,"ESTIMATED","INTERVENTIONAL",[76],"NA","The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.",[79,80,81],"Focal Epilepsy","Generalized Onset Epilepsy","Sleep-related Epileptic Encephalopathy","2026-01-26",{"date":84,"type":85},"2026-01-28","ACTUAL",{"date":87,"type":85},"2023-04-12",{"date":89,"type":73},"2026-12",{"name":5,"class":6},1]