[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582804":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":46,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":66,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Istituto Auxologico Italiano","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Patients with hypertension, aged 75 years and older",null,[12],"Diagnostic Test: Diagnostic tests and questionnaires",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DIAGNOSTIC_TEST","Diagnostic tests and questionnaires","Assessment of office blood pressure, orthostatic hypotension, 24-hour ambulatory blood pressure, frailty",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Alessandro Croce, MD","CONTACT","+3902619111","a.croce@auxologico.it",{"name":26,"role":22,"phone":23,"phoneExt":27,"email":28},"Luca Grappiolo, Dr.","2894","luca.grappiolo@auxologico.it",[30],{"facility":31,"status":32,"city":33,"state":10,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Istituto Auxologico Italiano IRCCS","RECRUITING","Milan","20145","Italy","IT",{"type":38,"coordinates":39},"Point",[40,41],9.18951,45.46427,{"lat":41,"lon":40},[44],{"name":21,"role":22,"phone":45,"phoneExt":10,"email":24},"+390261911",{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100582804","study-on-blood-pressure-variability-and-frailty-in-the-older-people-100582804",false,"NCT06868069","Study on Blood Pressure Variability and Frailty in the Older People","Study on Blood Pressure Variability and Frailty in the Older People: the HypoPHrail Study","HypoPHrail","Inclusion Criteria:\n\n* Age ≥ 75 years\n* Diagnosis of hypertension according to the criteria of the European Society of Cardiology guidelines \\[Williams 2018\\]\n* Consent of the patient (or legal representative) to participate in the study\n\nExclusion Criteria:\n\n* Refusal of the patient or his\u002Fher legal representative\n* Life expectancy of less than 6 months","ALL","75 Years",{"count":59,"type":60},220,"ESTIMATED","OBSERVATIONAL","Observational prospective single-center, non-profit study. Primary objective of the study: To determine if the hypotensive phenotype, defined as one episode of daytime systolic blood pressure (SBP) \\\u003C90 mmHg (or two episodes of daytime SBP \\\u003C90 mmHg, if mean 24 h SBP is \\\u003C125 mmHg) detected at Ambulatory Blood Pressure Monitoring (ABPM) is associated with adverse events at follow up (death, hospitalization, falls, emergency room admission for uncontrolled hypertension, major cardiovascular events)",[64,65],"Hypertension","Old Age",[67,68],"Blood pressure variability","Frailty","2026-03-25",{"date":71,"type":72},"2026-03-30","ACTUAL",{"date":74,"type":72},"2024-07-15",{"date":76,"type":60},"2027-07-15",{"name":5,"class":6},1]