[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586155":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":49,"collaborators":53,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":20,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":20,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":20,"overallStatus":30,"whyStopped":20,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Harbin Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: 18F-TSPF","EXPERIMENTAL","Each subject receives interval imaging of 18F-TSPF PET\u002FCT and 18F-FDG PET\u002FCT.",[13],"Diagnostic Test: 18F-TSPF PET\u002FCT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","18F-TSPF PET\u002FCT","Each subject receives interval imaging of 18F-TSPF PET\u002FCT and 18F-FDG PET\u002FCT, and further follow-up.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Xilin Sun, MD","CONTACT","+86-15904601908","sunxilin@aliyun.com",[28],{"facility":29,"status":30,"city":31,"state":32,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"Department of Nuclear Medicine, Fourth Affiliated Hospital of Harbin Medical University","RECRUITING","Harbin","Heilongjiang","150028","China","CN",{"type":37,"coordinates":38},"Point",[39,40],126.65,45.75,{"lat":40,"lon":39},[43,44,46],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},{"name":23,"role":45,"phone":20,"phoneExt":20,"email":20},"PRINCIPAL_INVESTIGATOR",{"name":47,"role":48,"phone":20,"phoneExt":20,"email":20},"Zhaoguo Han, MD","SUB_INVESTIGATOR",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"SPONSOR_INVESTIGATOR","Xilin Sun","Director",[54],{"name":55,"class":6},"Henan Provincial People's Hospital","100586155","study-on-c-met-targeted-petct-imaging-in-nsclc-100586155",false,"NCT06911697","Study on c-Met Targeted PET\u002FCT Imaging in NSCLC","In Vivo Detection of c-Met Activation Status by Specific PET\u002FCT Imaging Based on 18F Labeled Small Molecule TKI","Inclusion Criteria:\n\n1. Age range 18-75 years, open to both male and female participants;\n2. Normal hepatic\u002Frenal function and cardiac function;\n3. Expected survival of at least 12 weeks;\n4. Good adherence to follow-up;\n5. Presence of at least one measurable target lesion according to RECIST 1.1 criteria;\n6. Women of childbearing age (15-49 years) must undergo a pregnancy test within seven days prior to the commencement of the study and test negative; sexually active male and female participants must agree to utilize effective contraception to prevent pregnancy during the study and for three months following the final examination;\n7. Patients for whom a clinical physician recommends PET\u002FCT scans for the diagnosis and staging of tumors;\n8. Participants must fully understand and voluntarily agree to participate in the study, and must sign an informed consent form.\n\nExclusion Criteria:\n\n1. Severe abnormalities in liver and renal function and blood counts;\n2. Patients planning to conceive;\n3. Pregnant or lactating women;\n4. Individuals unable to lie flat for thirty minutes;\n5. Individuals who refuse to participate in this clinical study;\n6. Individuals suffering from claustrophobia or other psychiatric disorders;\n7. Other situations deemed unsuitable for trial participation by the researchers.",true,"ALL","18 Years","75 Years",{"count":68,"type":69},88,"ESTIMATED","INTERVENTIONAL",[72],"NA","The investigators developed a 18F labeled small molecule, 18F-TSPF, based on c-Met TKI, as a targeted molecular imaging agent for noninvasive and repeatable detecting c-Met activation status.",[75,76],"PET\u002FCT Imaging","NSCLC","2025-03-28",{"date":79,"type":80},"2025-04-04","ACTUAL",{"date":82,"type":80},"2023-10-26",{"date":84,"type":69},"2025-06-28",{"name":51,"class":6},1]