[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100432009":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":23,"locations":31,"responsibleParty":49,"collaborators":51,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":10,"eligibilityCriteria":67,"healthyVolunteers":64,"sex":68,"minAge":10,"maxAge":69,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":10,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Children's Hospital of Fudan University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Sick Neonates or Stillbirth",null,"Infants and their parents enrolled through Neonatal Intensive Care Unit or stillbirths through Obstetrics Department of member hospitals who are un-randomized to receive genomic sequencing. Results disclosure sessions will include a discussion of: family history report, results from standard newborn screening, any potentially medically relevant findings from the baby's medical history\u002F physical exam, and the results of the genomic sequencing report.",[13],"Other: No intervention",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"No intervention","It's only observational study. No interventions.",[9],[20],{"name":21,"affiliation":5,"role":22},"Wenhao Zhou","STUDY_CHAIR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":10,"email":27},"CONTACT","+86-21-64931913","zhouwenhao@fudan.edu.cn",{"name":29,"role":25,"phone":10,"phoneExt":10,"email":30},"Lin Yang","yanglin_fudan@163.com",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":10,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Shanghai","Shanghai Municipality","China","CN",{"type":39,"coordinates":40},"Point",[41,42],121.45806,31.22222,{"lat":42,"lon":41},[45,47],{"name":46,"role":25,"phone":26,"phoneExt":10,"email":27},"Wenhao Zhou, Doctor",{"name":48,"role":25,"phone":10,"phoneExt":10,"email":30},"Lin Yang, Doctor",{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[52,54,56,58,60],{"name":53,"class":6},"International Peace Maternity and Child Health Hospital",{"name":55,"class":6},"Obstetrics & Gynecology Hospital of Fudan University",{"name":57,"class":6},"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine",{"name":59,"class":6},"Shanghai Children's Medical Center",{"name":61,"class":6},"Shanghai Children's Hospital","100432009","study-on-early-genetic-screening-and-precise-strategy-of-neonatal-critical-illness-100432009",false,"NCT04905537","Study on Early Genetic Screening and Precise Strategy of Neonatal Critical Illness","Inclusion Criteria:\n\n* Postnatal age less than 100 days;\n* Perinatal death after 20 weeks of gestation (more than 500 g)\n* Can be retained biological samples for genetic screening;\n* Biological parent or guardian's informed consent.\n\nExclusion Criteria:\n\n* Reluctance of parents to use genetic sequencing data for subsequent research;\n* Parents under 18 years of age or incapacitated for decision-making;\n* subjects older than 100 days;\n* Perinatal death less than 20 weeks of gestation or weight less than 500 g;\n* Inherited metabolic diseases with chromosomal abnormalities;\n* Multiple pregnancies;\n* Lack of access to biological samples from which DNA can be extracted;\n* Failure to sign informed consent.","ALL","100 Days",{"count":71,"type":72},4000,"ESTIMATED","OBSERVATIONAL","The researchers hope to establish an overall program of early genetic screening for neonatal critical illness in China, and to develop precise intervention strategies to assist clinical diagnosis and treatment of hereditary critical illness.",[76,77,78,79],"Genetic Screening","Hereditary Disease","Newborn","Stillbirth","2025-02-19",{"date":82,"type":83},"2025-02-20","ACTUAL",{"date":85,"type":83},"2021-01-01",{"date":87,"type":72},"2025-12",{"name":5,"class":6},1]