[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572683":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":29,"locations":35,"responsibleParty":110,"collaborators":112,"id":116,"slug":117,"hasResults":118,"nctId":119,"briefTitle":120,"officialTitle":120,"acronym":28,"eligibilityCriteria":121,"healthyVolunteers":118,"sex":122,"minAge":123,"maxAge":28,"enrollmentInfo":124,"targetDuration":28,"studyType":127,"phases":128,"briefSummary":130,"conditions":131,"keywords":136,"overallStatus":38,"whyStopped":28,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":152},{"fullName":5,"class":6},"Artur Salgado SA","INDUSTRY",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Long-bone injuries","EXPERIMENTAL","Group formed by subjects with long-bone injuries treated using AdvanCore blocks, wedges, or granules.",[13],"Procedure: AdvanCore bone grafting",{"label":15,"type":10,"description":16,"interventionNames":17},"Spine injuries","Group formed by subjects with spine injuries treated using AdvanCore granules.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Maxillofacial injuries","Group formed by subjects with maxillofacial injuries treated using AdvanCore granules.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"PROCEDURE","AdvanCore bone grafting","AdvanCore medical device is implanted making sure that is in direct contact with all surfaces of the defect area.",[9,19,15],null,[30],{"name":31,"role":32,"phone":33,"phoneExt":28,"email":34},"Francisca C Costa","CONTACT","+351253794649","f.costa@artursalgado.pt",[36,58,76,93],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Unidade Local de Saúde do Alto Ave","RECRUITING","Guimarães","Braga District","4835-044","Portugal","PT",{"type":45,"coordinates":46},"Point",[47,48],-8.29619,41.44443,{"lat":48,"lon":47},[51,55],{"name":52,"role":32,"phone":53,"phoneExt":28,"email":54},"Ana Sofia F Costa","+351253540330","sofiafreitascosta@hospitaldeguimaraes.min-saude.pt",{"name":56,"role":57,"phone":28,"phoneExt":28,"email":28},"Carlos A Vilela Gomes, Orthopaedic surgeon","PRINCIPAL_INVESTIGATOR",{"facility":59,"status":60,"city":61,"state":62,"zip":63,"country":42,"countryCode":43,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Unidade Local de Saúde de São João","NOT_YET_RECRUITING","Porto","Porto District","4200-319",{"type":45,"coordinates":65},[66,67],-8.61097,41.1485,{"lat":67,"lon":66},[70,74],{"name":71,"role":32,"phone":72,"phoneExt":28,"email":73},"Teresa Burnay","+351225512100","ca@chsj.min-saude.pt",{"name":75,"role":57,"phone":28,"phoneExt":28,"email":28},"Teresa Burnay, Maxillofacial surgeon",{"facility":77,"status":60,"city":78,"state":79,"zip":80,"country":42,"countryCode":43,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Unidade Local de Saúde do Médio Tejo","Tomar","Santarém District","2304-909",{"type":45,"coordinates":82},[83,84],-8.40924,39.60199,{"lat":84,"lon":83},[87,91],{"name":88,"role":32,"phone":89,"phoneExt":28,"email":90},"Ana Rita B Reis","+351249320100","rita.reis@ulsmt.min-saude.pt",{"name":92,"role":57,"phone":28,"phoneExt":28,"email":28},"Amílcar J Valverde, Orthopaedic surgeon",{"facility":94,"status":38,"city":95,"state":96,"zip":97,"country":42,"countryCode":43,"cosmosGeoPoint":98,"geoPoint":102,"contacts":103},"Unidade Local de Saúde de Trás-os-Montes e Alto Douro","Lordelo","Vila Real District","5000-508",{"type":45,"coordinates":99},[100,101],-7.76652,41.31777,{"lat":101,"lon":100},[104,108],{"name":105,"role":32,"phone":106,"phoneExt":28,"email":107},"Catarina S dos Santos","+351259300500","cslsantos@chtmad.min-saude.pt",{"name":109,"role":57,"phone":28,"phoneExt":28,"email":28},"Carlos E Pintado, Orthopeadic Surgeon",{"type":111,"investigatorFullName":28,"investigatorTitle":28,"investigatorAffiliation":28,"oldNameTitle":28,"oldOrganization":28},"SPONSOR",[113],{"name":114,"class":115},"NAMSA","OTHER","100572683","study-on-safety-and-performance-of-advancore-bone-void-filler-100572683",false,"NCT06736457","Study on Safety and Performance of AdvanCore Bone Void Filler","Inclusion Criteria:\n\n* Adult subjects ≥ 18 years old, male or female.\n* Subjects who are eligible for a bone grafting\u002Fbone void filler procedure.\n* Subjects with bone lesions beyond the limits of the bone's self-healing ability.\n* Subjects, and\u002For an authorized representative, who are willing and capable of providing informed consent, participating in all testing associated with this clinical investigation at an approved clinical investigational center.\n* Subjects with only one fracture susceptible to treatment with an AdvanCore implant.\n\nExclusion Criteria:\n\n* Subjects with any AdvanCore contraindication for implantation or use.\n* Subjects with hypersensitivity to any of the AdvanCore components.\n* Subjects with infections or soft\u002Fgranulation tissue in the area to place bone graft.\n* Subjects who are currently enrolled in another investigational study or registry that would directly interfere with the current study.\n* Women who are breastfeeding or of childbearing potential who are, or plan to become, pregnant during the time of the study (method of assessment upon physician's discretion).","ALL","18 Years",{"count":125,"type":126},190,"ESTIMATED","INTERVENTIONAL",[129],"NA","The objective of this study is to evaluate the safety and performance of AdvanCore implantable bone graft through a 12-month follow-up period in a prospective, parallel-group design, non-controlled, open label, multi-center and real-world setting study. This study is intended to satisfy post-market clinical follow-up requirements of CE Mark in Europe.",[132,133,134,135],"Bone Fractures","Bone Defects","Bone Loss","Bone Graft",[137,138,139,140,141,142],"Bone graft","Bone substitute","Bone regeneration","AdvanCore","Beta-Tricalcium Phosphate","Synthetic bone graft","2025-05-30",{"date":145,"type":146},"2025-05-31","ACTUAL",{"date":148,"type":146},"2025-05-29",{"date":150,"type":126},"2026-10",{"name":5,"class":6},4]