[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607052":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":129,"collaborators":25,"id":132,"slug":133,"hasResults":134,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":138,"eligibilityCriteria":139,"healthyVolunteers":134,"sex":140,"minAge":141,"maxAge":142,"enrollmentInfo":143,"targetDuration":25,"studyType":146,"phases":147,"briefSummary":149,"conditions":150,"keywords":152,"overallStatus":157,"whyStopped":25,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":167},{"fullName":5,"class":6},"The Affiliated Hospital Of Guizhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"experimental group","EXPERIMENTAL","The autologous skull repair surgery will be completed within 6 weeks after the DC operation.",[13],"Procedure: operation opportunity-within 6 weeks after the DC operation.",{"label":15,"type":16,"description":17,"interventionNames":18},"control group","ACTIVE_COMPARATOR","The surgery should be completed within 90 to 180 days after DC.",[19],"Procedure: operation opportunity-within 90 to 180 days after the DC operation.",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","operation opportunity-within 6 weeks after the DC operation.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"operation opportunity-within 90 to 180 days after the DC operation.","The autologous skull repair surgery should be completed within 90 to 180 days after DC.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Kaya Xu","CONTACT","13984843194","xkaya@sina.com",[37,55,65,76,89,102,115],{"facility":38,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Anshun People's Hospital (Ward One)","Anshun","Guizhou","561000","China","CN",{"type":45,"coordinates":46},"Point",[47,48],105.93333,26.25,{"lat":48,"lon":47},[51],{"name":52,"role":33,"phone":53,"phoneExt":25,"email":54},"Wenyuan Tang, MM","13985312332","13985312332@qq.com",{"facility":56,"status":25,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":57,"geoPoint":59,"contacts":60},"Anshun People's Hospital (Ward Two)",{"type":45,"coordinates":58},[47,48],{"lat":48,"lon":47},[61],{"name":62,"role":33,"phone":63,"phoneExt":25,"email":64},"Hui Shuai, BMed","13985729194","13985729194@qq.com",{"facility":66,"status":25,"city":67,"state":40,"zip":25,"country":42,"countryCode":43,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"The First People's Hospital of Bijie City","Bijie",{"type":45,"coordinates":69},[70,71],105.28627,27.30193,{"lat":71,"lon":70},[74],{"name":75,"role":33,"phone":25,"phoneExt":25,"email":25},"Bingxiang Xiao, MD",{"facility":77,"status":25,"city":78,"state":40,"zip":25,"country":42,"countryCode":43,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Guizhou Provincial Workers' Hospital","Guiyang",{"type":45,"coordinates":80},[81,82],106.71667,26.58333,{"lat":82,"lon":81},[85],{"name":86,"role":33,"phone":87,"phoneExt":25,"email":88},"Guanghui Ran, BMed","18286059351","18286059351@qq.com",{"facility":90,"status":25,"city":91,"state":40,"zip":25,"country":42,"countryCode":43,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"Qianfengdong Prefecture People's Hospital","Kaili",{"type":45,"coordinates":93},[94,95],107.97972,26.58583,{"lat":95,"lon":94},[98],{"name":99,"role":33,"phone":100,"phoneExt":25,"email":101},"Jian Shen, MM","15985527337","15985527337@qq.com",{"facility":103,"status":25,"city":104,"state":40,"zip":25,"country":42,"countryCode":43,"cosmosGeoPoint":105,"geoPoint":109,"contacts":110},"Zunyi Medical University Affiliated Hospital","Zunyi",{"type":45,"coordinates":106},[107,108],106.90722,27.68667,{"lat":108,"lon":107},[111],{"name":112,"role":33,"phone":113,"phoneExt":25,"email":114},"Haitao Wu","18984980327","18984980327@qq.com",{"facility":116,"status":25,"city":117,"state":118,"zip":25,"country":42,"countryCode":43,"cosmosGeoPoint":119,"geoPoint":123,"contacts":124},"Neijiang First People's Hospital","Neijiang","Sichuan",{"type":45,"coordinates":120},[121,122],105.06216,29.58354,{"lat":122,"lon":121},[125],{"name":126,"role":33,"phone":127,"phoneExt":25,"email":128},"Cong Liu","13438640683","13438640683@qq.com",{"type":130,"investigatorFullName":32,"investigatorTitle":131,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100607052","study-on-the-effect-of-ultra-early-autologous-cranioplasty-on-neurological-function-recovery-100607052",false,"NCT07183540","Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery","Study on the Effect of Ultra-early Autologous Cranioplasty on Neurological Function Recovery: a Multicenter, Prospective, Open-label, Endpoint-blinded, Randomized Controlled Study","FAST-ECP","Inclusion Criteria:\n\n1. Decompressive craniectomy due to craniocerebral trauma, cerebral ischemia and cerebral hemorrhage.\n2. Age 18 - 80 years.\n3. The first time for cranial repair.\n4. unilateral skull defect.\n5. Compliant with recommended decompressive bone flap surgery and autogenous decompressive bone flap after bone flap collection\n6. signed the informed consent.\n\nExclusion Criteria:\n\n1. Poor healing of skin flap (active infection, non-healing, necrosis, sinus, thin or poor blood supply, etc.).\n2. Fracture of bone flap ≥2 pieces, partial open fracture\n3. Intracranial infection before operation.\n4. Severe bone metabolic diseases.\n5. Long-term use of immunosuppressants.\n6. Pregnant or lactating women.\n7. Coagulation disorders.\n8. Severe cardiopulmonary insufficiency.\n9. It is estimated that the CP process cannot be completed within 6 weeks after the bone plate decompression surgery.\n10. Skull defect size less than 25cm².\n11. Life expectancy less than 1 year.\n12. mRS greater than 1 before primary disease.\n13. Diabetic patients.\n14. Patients who are unable to cooperate with follow-up assessment (e.g. mental illness).","ALL","18 Years","80 Years",{"count":144,"type":145},582,"ESTIMATED","INTERVENTIONAL",[148],"NA","To compare the neurological recovery and complication rate of autogenous cranioplasty(CP) within 6 weeks after decompressive craniectomy (DC) with that of autogenous cranioplasty within 3\\~6 months after DC.",[151],"Cranial Defect",[153,154,155,156],"Decompressive craniectomy and Cranioplasty","operation opportunity","ultra-early","Autologous skull","NOT_YET_RECRUITING","2025-09-17",{"date":160,"type":161},"2025-09-19","ACTUAL",{"date":163,"type":145},"2025-10-01",{"date":165,"type":145},"2027-09-01",{"name":5,"class":6},7]