[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584970":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":45,"responsibleParty":72,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":26,"eligibilityCriteria":84,"healthyVolunteers":81,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":26,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":48,"whyStopped":26,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Huashan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TI stimulation group","EXPERIMENTAL","The two high-frequency electric fields of the TI device are set at different frequencies, thereby resulting in the generation of a low-frequency electric field that is capable of triggering brain physiological responses. The duration is 10 minutes.",[13],"Procedure: TI Stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham TI stimulation group","SHAM_COMPARATOR","The two high-frequency electric fields of the TI device are set to be completely of the same frequency (2000Hz), thus no low-frequency electric field is produced and no cerebral physiological responses are elicited. The duration lasts for 10 minutes.",[19],"Procedure: Sham Stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","TI Stimulation","Participants will accept the TI stimulus for one month",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham Stimulation","Participants will accept the sham TI stimulus for one month",[15],[32],{"name":33,"affiliation":34,"role":35},"Xuehai Wu, Ph.D.","Department of Neurosurgery, Huashan Hospital, Fudan University","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+86 13764880571","Wuxuehai2013@163.com",{"name":42,"role":38,"phone":43,"phoneExt":26,"email":44},"Wentao Huang, M.M.","+86 19370557372","hhuangwt7777@163.com",[46,65],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Department of neurological rehabilitation, Shanghai First Rehabilitation Hospital, Tongji University","RECRUITING","Shanghai","Shanghai Municipality","200000","China","CN",{"type":55,"coordinates":56},"Point",[57,58],121.45806,31.22222,{"lat":58,"lon":57},[61],{"name":62,"role":38,"phone":63,"phoneExt":26,"email":64},"Anjing Zhang, Ph.D.","+86 18930133551","sunnylovely_aj@163.com",{"facility":34,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},{"type":55,"coordinates":67},[57,58],{"lat":58,"lon":57},[70],{"name":33,"role":38,"phone":71,"phoneExt":26,"email":40},"+8613764880571",{"type":35,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Xuehai Wu","Deputy Director of Shanghai Neurosurgical Emergency Center",[76],{"name":77,"class":78},"Shanghai First Rehabilitation Hospital","UNKNOWN","100584970","study-on-the-effectiveness-and-safety-of-temporal-interference-stimulation-in-treating-patients-with-severe-consciousness-disorders-100584970",false,"NCT06896279","Study on the Effectiveness and Safety of Temporal Interference Stimulation in Treating Patients With Severe Consciousness Disorders","Inclusion Criteria:\n\n* Severe consciousness disorder patients aged 18 to 75 years old, regardless of gender;\n* Patients with severe consciousness disorders, namely a minimally conscious state or vegetative state that lasts for 28 days or more;\n* Patients with normal body temperature, stable vital signs, spontaneous breathing, tracheotomy without the use of a metal cannula and with a small amount of sputum, and who are eligible for magnetic resonance imaging (MRI) examination;\n* Written informed consent obtained from the patient's family members in advance.\n\nExclusion Criteria:\n\n* Individuals with a previous history of significant neuropsychiatric and other major disorders such as those involving the heart, lung, liver, and kidney;\n* Those who have undergone V-P shunt or Ommaya reservoir implantation and other procedures that may influence the analysis of magnetic resonance scanning signals;\n* Patients who are scheduled for V-P shunt or Ommaya reservoir implantation in the near future;\n* Pregnant women;\n* Those who have participated in other drug or device clinical trials;\n* Patients with poorly controlled epilepsy in the recent period;\n* Those with infections at the TI stimulation site or compromised skin integrity at the electrode placement site;\n* Those currently taking medications prone to inducing epilepsy, such as quinolone drugs;\n* Those with intracranial infections, intracranial tumors, or metallic objects within the cranium;\n* Those allergic to electrode gel or adhesives;\n* Those with implanted electronic devices within the body;\n* Those with severe cardiac disorders and those equipped with cardiac pacemakers.","ALL","18 Years","75 Years",{"count":89,"type":90},20,"ESTIMATED","INTERVENTIONAL",[93],"NA","Investigating the efficacy and safety of temporal interference stimulation for patients with disorders of consciousness.",[96,97],"Disorder of Consciousness","Temporal Interference Stimulation",[96,99,97],"Randomized clinical trail","2025-12-08",{"date":102,"type":103},"2025-12-16","ACTUAL",{"date":105,"type":103},"2025-04-21",{"date":107,"type":90},"2026-05-17",{"name":5,"class":6},2]