[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582858":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":28,"locations":33,"responsibleParty":50,"collaborators":22,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":22,"enrollmentInfo":62,"targetDuration":22,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":22,"overallStatus":36,"whyStopped":22,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Societa Italiana di Dermatologia Medica, Chirurgica, Estetica e di Malattie Sessualmente Trasmesse","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"cases","topical treatment with the pre- and postbiotic and niacinamide 4% study preparation",[12],"Other: topical treatment with the pre- and postbiotic study preparation and niacinamide 4% and one with the 10% urea-based preparation.",{"label":14,"type":6,"description":15,"interventionNames":16},"control","prepared from 10% urea.",[12],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"topical treatment with the pre- and postbiotic study preparation and niacinamide 4% and one with the 10% urea-based preparation.","Application of the topical preparation in both groups will be performed twice a day for a total duration of 3 months.",[9,14],null,[24],{"name":25,"affiliation":26,"role":27},"Ketty MD Peris","IRCCS FONDAZIONE POLICLINICO GEMELLI","PRINCIPAL_INVESTIGATOR",[29],{"name":25,"role":30,"phone":31,"phoneExt":22,"email":32},"CONTACT","0630154211","ketty.peris@unicatt.it",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Irccs Fondazione Policlinico Gemelli","RECRUITING","Roma","ROMA","00168","Italy","IT",{"type":43,"coordinates":44},"Point",[45,46],11.10642,44.99364,{"lat":46,"lon":45},[49],{"name":25,"role":30,"phone":31,"phoneExt":22,"email":32},{"type":51,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100582858","study-on-the-effectiveness-of-an-emollient-cream-containing-pre-and-postbiotic-and-niacinamide-4-in-the-treatment-of-skin-xerosis-and-itching-in-oncological-patients-treated-with-anti-egfr-100582858",false,"NCT06868771","Study on the Effectiveness of an Emollient Cream Containing Pre and Postbiotic and Niacinamide 4% in the Treatment of Skin Xerosis and Itching in Oncological Patients Treated with Anti-EGFR","Studio Sulla Efficacia Di Una Crema Emolliente Contenente Pre E Postbiotici E Niacinamide 4% Nel Trattamento Della Xerosi Cutanea E Del Prurito in Pazienti Oncologici in Trattamento Con Anti-EGFR","PENSANTE","Inclusion Criteria:\n\n1. patients aged 18 who have been receiving anti-EGFR therapy for more than three months,\n2. signature of the informed consent.\n\nExclusion Criteria:\n\n1. Patients diagnosed with Grade II papulopustulous skin reaction according to the Common Terminology Criteria for Adverse Event (CTCAE) scale at the time of enrolment;\n2. concomitant use of emollients and\u002For steroidal creams;\n3. personal history of xerotic pathologies (e.g. lichen, ichthyosis) and\u002For itching of n.d.d.;\n4. inability to provide informed consent or inability to complete the procedures required for enrollment in the study.","ALL","18 Years",{"count":63,"type":64},164,"ESTIMATED","INTERVENTIONAL",[67],"NA","Study on the Effectiveness of an Emollient Cream Containing Pre and Postbiotic and Niacinamide 4% in the Treatment of Skin Xerosis and Itching in Oncological Patients Treated With Anti-EGFR.",[70],"Xerosis Cutis","2025-03-04",{"date":73,"type":74},"2025-03-11","ACTUAL",{"date":76,"type":74},"2022-07-29",{"date":78,"type":64},"2025-04-30",{"name":5,"class":6},1]