[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575458":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":47,"centralContacts":51,"locations":35,"responsibleParty":57,"collaborators":35,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":35,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":35,"enrollmentInfo":70,"targetDuration":35,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":35,"overallStatus":79,"whyStopped":35,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":35},{"fullName":5,"class":6},"Inner Mongolia Baogang Hospital","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"EA","EXPERIMENTAL","Epidural Analgesia",[13],"Procedure: Epidural Analgesia",{"label":15,"type":10,"description":16,"interventionNames":17},"PB","Paravertebral Block",[18],"Device: Paravertebral Block",{"label":20,"type":10,"description":21,"interventionNames":22},"TAP","Transversus Abdominis Plane Block",[23],"Device: Transversus Abdominis Plane Block",{"label":25,"type":26,"description":27,"interventionNames":28},"PCIA","ACTIVE_COMPARATOR","Patient-Controlled Intravenous Analgesia",[29],"Device: patient-controlled intravenous analgesia (PCA)",[31,36,40,43],{"type":32,"name":11,"description":33,"armGroupLabels":34,"otherNames":35},"PROCEDURE","Patients in the EA group underwent epidural anesthesia after admission to the operating room. Following successful epidural puncture, 3 ml of 2% lidocaine was administered. Once the block level was confirmed, the epidural analgesia pump was activated, delivering 8 ml\u002Fh of 0.1% ropivacaine.",[9],null,{"type":37,"name":16,"description":38,"armGroupLabels":39,"otherNames":35},"DEVICE","Using an in-plane technique, the puncture needle was advanced from lateral to medial under real-time ultrasound guidance to the target paravertebral space, passing through the intercostal fascia, avoiding the parietal pleura, and positioning the needle tip superior to the costotransverse ligament. After confirming needle tip placement, 10 mL of 0.5% ropivacaine was slowly injected in divided doses, observing for the spread of the local anesthetic to ensure adequate distribution within the PVS for effective block.",[15],{"type":37,"name":21,"description":41,"armGroupLabels":42,"otherNames":35},"The plane of blockade and whether to perform a single or double injection technique were determined based on the incision location. Under real-time ultrasound guidance, the puncture needle was advanced to the target transversus abdominis plane. After confirming needle tip placement, 10 mL of 0.5% ropivacaine was injected slowly in a fractionated manner while observing the local anesthetic spread to ensure effective blockade.",[20],{"type":37,"name":44,"description":45,"armGroupLabels":46,"otherNames":35},"patient-controlled intravenous analgesia (PCA)","The patient-controlled analgesia (PCA) device was programmed to deliver bolus doses of 15 μg fentanyl, with a 10-minute lockout period and no background infusion. The PCA solution consisted of 1 mg fentanyl and 8 mg of tropisetron mixed in 100 mL of normal saline.",[25],[48],{"name":49,"affiliation":5,"role":50},"Xiangyu Wang, MM","PRINCIPAL_INVESTIGATOR",[52],{"name":53,"role":54,"phone":55,"phoneExt":35,"email":56},"Xiaguang Duan, Master's degree","CONTACT","+86 13314720012","alonlord2023@gmail.com",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"SPONSOR_INVESTIGATOR","Xiaguang Duan","Deputy Chief of Anesthesiology","100575458","study-on-the-effects-of-multimodal-analgesia-regimens-on-postoperative-analgesia-and-gastrointestinal-function-recovery-after-laparoscopic-abdominal-surgery-100575458",false,"NCT06772545","Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery","A Prospective Comparative Study on the Effects of Multimodal Analgesia Regimens on Postoperative Analgesia and Gastrointestinal Function Recovery After Laparoscopic Abdominal Surgery","Inclusion Criteria:\n\n* \\>18 years old\n* ASA I-III\n* Ability to understand and voluntarily sign the informed consent form\n* No prior use of long-acting or addictive analgesic drugs before surgery.\n\nExclusion Criteria:\n\n* History of previous abdominal surgery\n* Presence of severe cardiovascular, respiratory, hepatic, renal, neurological, or psychiatric disorders\n* Pre-existing chronic pain conditions\n* Known allergy to any analgesic drugs used in this study\n* Presence of spinal deformities, neurological conditions, or coagulopathy that may affect the performance of regional anesthesia.\n* Pregnant or breastfeeding women\n* Inability to cooperate with study procedures or understand pain rating scales\n* History of opioid abuse or addiction.","ALL","18 Years",{"count":71,"type":72},120,"ESTIMATED","INTERVENTIONAL",[75],"NA","This clinical trial aims to investigate the impact of multimodal analgesia regimens on postoperative pain management and gastrointestinal function recovery following laparoscopic abdominal surgery. The primary objectives are to determine:\n\nWhich analgesic regimen is most effective in reducing postoperative pain? Which analgesic regimen is most effective in accelerating gastrointestinal function recovery? This study will compare epidural analgesia (EA), paravertebral block (PB), transversus abdominis plane block (TAP), and patient-controlled intravenous analgesia (PCIA) to identify the optimal method for pain control and the most beneficial for gastrointestinal recovery.\n\nParticipants will receive one of the following treatments postoperatively: epidural analgesia, paravertebral block, TAP block, or patient-controlled intravenous analgesia. Rest pain (measured using the Numerical Rating Scale, NRS), dynamic pain (NRS), morphine equivalent consumption (mg), quality of sleep on the first night (Likert scale, 1-5), time to return of bowel function (h), time to recommence oral intake (h), time to first mobilization (h), quality of recovery (QoR, 0-15) on postoperative day 1, and length of hospital stay (days) will be recorded at 4, 8, 12, and 24 hours post-procedure.",[78],"Laparoscopic Abdominal Surgery","NOT_YET_RECRUITING","2025-01-12",{"date":82,"type":83},"2025-01-14","ACTUAL",{"date":85,"type":72},"2025-02-01",{"date":87,"type":72},"2025-05-10",{"name":59,"class":6}]