[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582446":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":31,"responsibleParty":52,"collaborators":26,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":26,"eligibilityCriteria":60,"healthyVolunteers":61,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":26,"overallStatus":74,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Wecare Probiotics Co., Ltd.","INDUSTRY",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Probiotic Group","EXPERIMENTAL","Intervention with Bifidobacterium longum subsp. infantis BI45 (30 billion CFU\u002F day, 3g) was administered daily for 8 weeks. Store in a cool, dry place.",[13],"Dietary Supplement: Probiotic",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo Group","PLACEBO_COMPARATOR","Every day to give 3 g maltodextrin intervention for 8 weeks. Store in a cool and dry place.",[19],"Dietary Supplement: Placebo",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DIETARY_SUPPLEMENT","Probiotic","Dietary supplement: Probiotics. The trial period of this study lasts for 2 months (8 weeks), during which each participant will have 3 visits (at month 0, month 1, and month 2).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Placebo","Dietary supplement: Placebo. The trial period of this study lasts for 2 months (8 weeks), during which each participant will have 3 visits (at month 0, month 1, and month 2).",[15],[32],{"facility":33,"status":26,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"Henan University of Technology","Zhengzhou","Henan","462000","China","CN",{"type":40,"coordinates":41},"Point",[42,43],113.64861,34.75778,{"lat":43,"lon":42},[46],{"name":47,"role":48,"phone":49,"phoneExt":50,"email":51},"Fei Xu, Doctor","CONTACT","13671979116","+86","xu.fei@haut.edu.cn",{"type":53,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100582446","study-on-the-enhancement-of-intestinal-and-immune-functions-through-probiotic-intervention-100582446",false,"NCT06863415","Study on the Enhancement of Intestinal and Immune Functions Through Probiotic Intervention","A Study on the Safety and Effectiveness of Bifidobacterium Longum Subsp. infantisBI45 in Improving Intestinal and Immune Functions","Inclusion Criteria:\n\n1. Willing to undergo 3 follow-up visits during the intervention period Be willing to provide blood, urine and stool samples 2 times during the intervention period\n2. Willing to self-administer probiotic or placebo once a day during the intervention period\n3. Good eyesight, can read and write, can wear glasses\n4. Have good hearing and be able to hear and understand all instructions during the intervention\n\nExclusion Criteria:\n\n1. Digestive diseases, mainly gastrointestinal diseases (celiac disease, ulcerative colitis, Crohn's disease)\n2. Have a serious neurological condition (epilepsy, stroke, severe head trauma, meningitis in the last 10 years, brain surgery, brain tumor, prolonged coma - not including general anaesthesia)\n3. Have received\u002Fare receiving treatment for the following mental disorders: alcohol\u002Fdrug\u002Fsubstance abuse dependence, schizophrenia, psychosis, bipolar disorder\n4. Take medication for depression or low mood Internal organ failure (heart, liver or kidney failure, etc.)\n5. Have received radiation or chemotherapy in the past\n6. Have undergone a general anesthesia procedure\u002Fprocedure within the past three years, or plan to undergo a general anesthesia procedure\u002Fprocedure within the next 3 months during this trial period\n7. Have had hepatitis (hepatitis B, hepatitis C), HIV or syphilis in the past",true,"ALL","18 Years","45 Years",{"count":66,"type":67},90,"ESTIMATED","INTERVENTIONAL",[70],"NA","Evaluate the effectiveness and safety of Bifidobacterium longum subsp. infantis BI45 as a food supplement compared to a placebo in improving intestinal and immune functions in healthy adults.",[73],"Healthy","NOT_YET_RECRUITING","2025-03-06",{"date":77,"type":78},"2025-03-10","ACTUAL",{"date":80,"type":67},"2025-03-15",{"date":82,"type":67},"2025-12-25",{"name":5,"class":6},1]