[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589505":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":10,"centralContacts":28,"locations":34,"responsibleParty":54,"collaborators":10,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Chongqing Medical University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients With Primary Aldosteronism",null,"primary aldosteronism patients underwent surgical treatment and completed the ACTH stimulation test",[13],"Diagnostic Test: complete ACTH stimulation test the day after surgery and complete ACTH stimulation test 1 or 4 week for patients with Adrenal Insufficiency",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients With Primary Aldosteronism Concurrent With Autonomous Cortisol Secretion","primary aldosteronism patients concurrent with autonomous cortisol secretion underwent surgical treatment and completed the ACTH stimulation test",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Patients With With Autonomous Cortisol Secretion","patients with autonomous cortisol secretion underwent surgical treatment and completed the ACTH stimulation test",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"DIAGNOSTIC_TEST","complete ACTH stimulation test the day after surgery and complete ACTH stimulation test 1 or 4 week for patients with Adrenal Insufficiency","patients complete ACTH stimulation test on the one day after surgery and complete ACTH stimulation test 1 or 4 week for patients with Adrenal Insufficiency",[9,15,19],[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Li Qifu, PhD","CONTACT","+86-023-89011552","liqifu@yeah.net",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"the First Affiliated Hospital of Chongqing Medical University, Chongqing, China","RECRUITING","Chongqing","Chongqing Municipality","400016","China","CN",{"type":44,"coordinates":45},"Point",[46,47],106.55771,29.56026,{"lat":47,"lon":46},[50,51],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},{"name":52,"role":31,"phone":32,"phoneExt":10,"email":53},"Yang Shuming, PhD","443068494@qq.com",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Qifu Li","Primary investigator","100589505","study-on-the-incidence-of-adrenal-insufficiency-after-surgery-in-primary-aldosteronism-patients-concurrent-with-or-without-autonomous-cortisol-secretion-100589505",false,"NCT06955286","Study on the Incidence of Adrenal Insufficiency After Surgery in Primary Aldosteronism Patients Concurrent With or Without Autonomous Cortisol Secretion","* A confirmed diagnosis of primary aldosteronism or autonomous cortisol secretion;\n\n  ② Completion of unilateral adrenal surgery;\n\n  ③ Voluntary participation and obtaining informed consent. (2) Exclusion criteria\n* Patients with typical clinical manifestations of Cushing's syndrome;\n\n  * Patients suspected of having bilateral cortisol over-secretion, such as PBMAH or PPNAD; ③ Patients with severe surgical complications, unstable postoperative condition (not due to cortical insufficiency), and difficulty completing the ACTH stimulation test;\n\n    * History of ACTH allergy;\n\n      * Patients requiring long-term hormone therapy for other diseases (such as autoimmune diseases);\n\n        * Severe liver and kidney dysfunction (ALT ≥ 3 times the upper limit of normal; patients undergoing dialysis or with an estimated glomerular filtration rate \\\u003C 30 ml\u002Fmin\u002Fm2); ⑦ History of contralateral adrenal surgery; ⑧ Patients with poor compliance who are unable to complete the study.","ALL","18 Years","70 Years",{"count":68,"type":69},521,"ESTIMATED","OBSERVATIONAL","To evaluate the incidence of adrenal insufficiency after surgery in Primary aldosteronism (PA) patients concurrent with or without autonomous cortisol secretion (ACS). To assess the recovery time of postoperative adrenal insufficiency in patients. And to explore the clinical characteristics and predictive indicators of patients requiring postoperative hormone replacement therapy.",[73,74,75],"Primary Aldosteronism","Autonomous Cortisol Secretion","Adrenal Insufficiency",[73,74,75,77],"ACTH stimulation test","2026-04-29",{"date":80,"type":81},"2026-05-01","ACTUAL",{"date":83,"type":81},"2025-01-02",{"date":85,"type":69},"2028-12-31",{"name":56,"class":6},1]