[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584726":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":35,"responsibleParty":55,"collaborators":20,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":20,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":20,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":77,"overallStatus":38,"whyStopped":20,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University of Fujairah","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Intentional Replantation of Hopeless Periodontally Involved Single-Rooted Teeth","EXPERIMENTAL","This study evaluates the outcomes of intentional replantation of hopeless periodontally involved single-rooted teeth using a pre-test, post-test interventional design.\n\nAt baseline, clinical and CBCT assessments will be performed to evaluate alveolar bone levels, periodontal status, and tooth mobility. The intervention involves atraumatic extraction, extraoral conditioning (if needed), and replantation with stabilization.\n\nAt 9 months, follow-up CBCT and clinical evaluations will assess bone changes, periodontal healing, and tooth stability.",[13],"Procedure: Intentional Replantation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Intentional Replantation","The intervention involves intentional replantation (IR) of periodontally compromised single-rooted teeth. Patients are selected based on criteria ensuring no vertical root fractures and potential for restoration. Preoperative preparation includes radiographic evaluation (CBCT\u002Fperiapical), scaling, and root planing, along with antibiotic prophylaxis. The tooth is extracted non-traumatically using periotomes to preserve the periodontal ligament (PDL). After extraction, the tooth is stored in a sterile medium and granulation tissue is excised. Optional modifications (apical resection, retrograde filling, or surface treatment) may be performed. The tooth is then replanted into the socket, secured with a non-rigid splint, and occlusal adjustment is made. Postoperative care includes analgesics, antibiotics, and chlorhexidine rinse. Follow-ups are scheduled at 1 week, 4 weeks, and 9 months for evaluation of healing, survival, and patient-reported outcomes.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Nabeel Ayappali Kalluvalappil, MDS","Lecturer, College of Dentistry, University of Fujairah, UAE, Zip Code 2202","PRINCIPAL_INVESTIGATOR",[27,31],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},"CONTACT","+971504614791","nabeelsabeel@gmail.com",{"name":32,"role":28,"phone":33,"phoneExt":20,"email":34},"Tamer Hamed Hassan, PhD","+971902023500","t.hassan@uof.ac.ae",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Dental Clinic, College of Dentistry, University of Fujairah,","RECRUITING","Fujairah","Emirate of Fujairah","2202","United Arab Emirates","AE",{"type":45,"coordinates":46},"Point",[47,48],56.34141,25.11641,{"lat":48,"lon":47},[51,52],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},{"name":32,"role":28,"phone":53,"phoneExt":54,"email":34},"+97192023500","501",{"type":56,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100584726","study-on-treatment-results-and-bone-changes-after-replanting-severely-affected-teeth---a-before-and-after-study-100584726",false,"NCT06893107","Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.","Assessment of Treatment Outcomes and Alveolar Bone Changes Following Intentional Replantation of Hopeless Periodontally Involved Single-Rooted Teeth - A Pre-test, Post-test Interventional Study","Inclusion Criteria:\n\nPatients meeting the specified criteria will be included in the study.\n\n* The patients with American Society of Anesthesiologists physical status classification 1 and 2.\n* Radiographic bone loss of at least 50% around the targeted tooth.\n* Probing depth of at least 5 millimetres around the targeted tooth.\n* Grade III mobility (extreme mobility) of the targeted tooth according to Miller's classification.\n* Grade II mobility or less (minimal to slight increased mobility without functional impairment) of adjacent teeth.\n* Distance between the targeted tooth and adjacent teeth less than 2 millimetres.\n* Patient preference for tooth retention through intentional replantation over extraction.\n\nExclusion Criteria:\n\n* Previous history of failed IR.\n* Severe anatomical limitations in the treatment area.\n* Unwillingness to adhere to follow-up protocols",true,"ALL","18 Years","70 Years",{"count":69,"type":70},45,"ESTIMATED","INTERVENTIONAL",[73],"NA","This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true periodontic lesions. The study will assess changes in alveolar bone and periodontal tissues, symptom resolution, and patient-reported outcomes (satisfaction and quality of life) following the procedure. Cone beam computed tomography (CBCT) imaging will be used to track radiographic changes at baseline and 9 months, while clinical examinations will monitor symptom resolution, including pain, swelling, and tooth mobility.\n\nThe study is a single-arm pre-test, post-test interventional design conducted at the College of Dentistry, University of Science and Technology Fujairah (new name: University of Fujairah). Participants will include adults aged 18-70 with single-rooted teeth deemed hopeless due to periodontic lesions. Participants will undergo intentional replantation, and data will be collected through clinical examinations, radiographic images, and patient questionnaires at baseline and 9 months.\n\nStatistical analysis will compare pre- and post-treatment outcomes using paired-samples t-tests or Wilcoxon signed-rank tests, depending on data normality. The study aims to provide a comprehensive evaluation of intentional replantation, contributing valuable insights into its clinical effectiveness for managing complex dental conditions.",[76],"Chronic Periodontitis",[78,79,80],"Chronic periodontitis","Periodontally compromised tooth","Intentional replantation","2025-11-20",{"date":83,"type":84},"2025-11-26","ACTUAL",{"date":86,"type":84},"2024-03-25",{"date":88,"type":70},"2026-03-15",{"name":5,"class":6},1]