[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595097":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":27,"locations":33,"responsibleParty":49,"collaborators":10,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":10,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences","OTHER",[8,12,15,18,21,24],{"label":9,"type":10,"description":11,"interventionNames":10},"Volunteers from Beijing",null,"A total of 50 local volunteers will be recruited in Beijing to participate in the study. The study procedures will include height measurement, body composition analysis, body water turnover assessment, water intake documentation, physical activity level monitoring, and evaluation of environmental factors (temperature, humidity, and altitude).",{"label":13,"type":10,"description":14,"interventionNames":10},"Volunteers from Shenzhen","A total of 50 local volunteers will be recruited in Shenzhen to participate in the study. The study procedures will include height measurement, body composition analysis, body water turnover assessment, water intake documentation, physical activity level monitoring, and evaluation of environmental factors (temperature, humidity, and altitude).",{"label":16,"type":10,"description":17,"interventionNames":10},"Volunteers from Shenyang","A total of 50 local volunteers will be recruited in Shenyang to participate in the study. The study procedures will include height measurement, body composition analysis, body water turnover assessment, water intake documentation, physical activity level monitoring, and evaluation of environmental factors (temperature, humidity, and altitude).",{"label":19,"type":10,"description":20,"interventionNames":10},"Volunteers from Yantai","A total of 50 local volunteers will be recruited in Yantai to participate in the study. The study procedures will include height measurement, body composition analysis, body water turnover assessment, water intake documentation, physical activity level monitoring, and evaluation of environmental factors (temperature, humidity, and altitude).",{"label":22,"type":10,"description":23,"interventionNames":10},"Volunteers from Xining","A total of 50 local volunteers will be recruited in Xining to participate in the study. The study procedures will include height measurement, body composition analysis, body water turnover assessment, water intake documentation, physical activity level monitoring, and evaluation of environmental factors (temperature, humidity, and altitude).",{"label":25,"type":10,"description":26,"interventionNames":10},"Volunteers from Wenzhou","A total of 50 local volunteers will be recruited in Wenzhou to participate in the study. The study procedures will include height measurement, body composition analysis, body water turnover assessment, water intake documentation, physical activity level monitoring, and evaluation of environmental factors (temperature, humidity, and altitude).",[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Xueying Zhang","CONTACT","+8618201296155","zhangxy@siat.ac.cn",[34],{"facility":35,"status":36,"city":35,"state":37,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Beijing","RECRUITING","Beijing Municipality","China","CN",{"type":41,"coordinates":42},"Point",[43,44],116.39723,39.9075,{"lat":44,"lon":43},[47],{"name":48,"role":30,"phone":10,"phoneExt":10,"email":10},"Yukun Liu",{"type":50,"investigatorFullName":29,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Principal Investigator","100595097","study-on-water-turnover-of-the-chinese-population-based-on-deuterium-dilution-method-100595097",false,"NCT07028021","Study on Water Turnover of the Chinese Population Based on Deuterium Dilution Method","Inclusion Criteria:\n\n1. Stable body weight over the past year\n2. Ability to perform normal physical activities\n\nExclusion Criteria:\n\n1. History of chronic diseases such as diabetes, liver disease, kidney disease, or any other conditions that may affect fluid metabolism\n2. Use of diuretics or other medications that influence urine output\n3. Pregnancy or breastfeeding",true,"ALL","18 Years",{"count":62,"type":63},300,"ESTIMATED","OBSERVATIONAL","Water is essential for sustaining life and maintaining health. The human body relies on water to transport nutrients and waste products, lubricate joints, regulate body temperature, and preserve tissue structure. International research has shown that losing just 2% of body weight through water loss can impair physiological functions and reduce response capacity. Adequate water intake plays a crucial protective role in health: it helps regulate body weight, lowers the risk of chronic diseases such as cardiovascular and cerebrovascular conditions, and supports cognitive function.\n\nHowever, the common recommendation to drink eight cups of water per day lacks strong scientific evidence. Most national hydration guidelines are based on average population intake, and personalized water intake recommendations have yet to be fully developed.\n\nIn this study, the investigators will use the deuterium dilution technique to measure water turnover in volunteers. Body composition will be assessed using the TANITA MC-780, while a seven-day fluid intake diary will track daily water consumption. Physical activity levels will be monitored using GT3 devices, and environmental data-including altitude, temperature, and humidity-will be collected based on participants' locations.\n\nThe goal of this study is to collect comprehensive data on the physiological traits, environmental influences, and hydration needs of the Chinese population. This will allow for refinement and optimization of current prediction equations for water requirements. Ultimately, the investigators aim to develop a new, individualized water intake algorithm tailored to the Chinese population by quantifying the proportion of water intake relative to total water requirements.",[67,68,69],"Water Turnover","Population Water Requirements","Deuterium Dilution","2025-06-17",{"date":72,"type":73},"2025-06-19","ACTUAL",{"date":75,"type":73},"2025-05-06",{"date":77,"type":63},"2026-10-30",{"name":5,"class":6},1]