[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614881":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":37,"locations":45,"responsibleParty":64,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":18,"enrollmentInfo":81,"targetDuration":18,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":48,"whyStopped":18,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"AC Camargo Cancer Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Surgical Gloves","EXPERIMENTAL","During each chemotherapy cycle, patients in the experimental arm will wear compressive surgical gloves (0.5 size smaller than recommended based on palmar surface measurement) on both hands, which will be put on 30 minutes before the infusion and remain in place until 30 minutes after the end of the chemotherapy infusion.",[13],"Device: Surgical Gloves",{"label":15,"type":16,"description":17,"interventionNames":18},"No Surgical Gloves","NO_INTERVENTION","The control arm will receive treatment according to current recommendations without the use of any devices on the hands.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":18},"DEVICE","During each chemotherapy cycle, patients in the experimental group will wear compressive surgical gloves (one size smaller than recommended based on palmar surface measurement) on both hands, which will be put on 30 minutes before the infusion and remain in place until 30 minutes after the end of the chemotherapy infusion.",[9],[25,29,33,35],{"name":26,"affiliation":27,"role":28},"Bruna Catin Kupper, Nurse, PhD","AC Camarco Cancer Center","STUDY_CHAIR",{"name":30,"affiliation":31,"role":32},"Éverton Germano Melo, Medical Doctor","Londrina Cancer Hospital","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":5,"role":32},"Virgilio Souza Silva, Medical Doctor, PhD",{"name":36,"affiliation":5,"role":28},"Karina Oliveira Ribeiro, Nurse",[38,42],{"name":34,"role":39,"phone":40,"phoneExt":18,"email":41},"CONTACT","+55 (11) 2189-5000","virss2013@gmail.com",{"name":30,"role":39,"phone":43,"phoneExt":18,"email":44},"+55 (43) 3379-2600","evertongermanomelo@gmail.com",[46],{"facility":47,"status":48,"city":49,"state":49,"zip":18,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"A.C. Camargo Cancer Center","RECRUITING","São Paulo","Brazil","BR",{"type":53,"coordinates":54},"Point",[55,56],-46.63611,-23.5475,{"lat":56,"lon":55},[59],{"name":60,"role":39,"phone":61,"phoneExt":62,"email":63},"Bruna Kupper","+551121895010","2832","bruna.catin@accamargo.org.br",{"type":32,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Virgilio Souza e Silva","Doctor and Head Oncologist of the Clinical Oncology Department at AC Camargo Cancer Center",[68],{"name":69,"class":70},"Hospital do Cancer de Londrina","UNKNOWN","100614881","study-to-evaluate-the-use-of-surgical-gloves-for-the-prevention-of-oxaliplatin-induced-peripheral-neuropathy-100614881",false,"NCT07285356","Study to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy","GLOX-PEN: Phase II Clinical Trial to Evaluate the Use of Surgical Gloves for the Prevention of Oxaliplatin-Induced Peripheral Neuropathy","GLOX-PEN","Inclusion Criteria:\n\n* Patients aged 18 years or older who have provided written informed consent.\n* Colon adenocarcinoma with high-risk stage III (pT4pN2) or stage IV.\n* Oxaliplatin-based treatment in the context of localized or metastatic disease.\n* Eastern Cooperative Oncology Group (ECOG) performance status of 0-1.\n\nExclusion Criteria:\n\n* Pre-existing neuropathy.\n* Uncontrolled diabetes.\n* known glove allergies.\n* Prior treatment with paclitaxel, docetaxel or oxaliplatin.","ALL","18 Years",{"count":82,"type":83},84,"ESTIMATED","INTERVENTIONAL",[86],"NA","The primary objective of this randomized clinical trial is to assess whether the use of surgical gloves during treatment can prevent the occurrence of oxaliplatin-induced peripheral neuropathy.",[89,90],"Colon Cancer","Oxaliplatin-induced Peripheral Neuropathy",[92,93,94,9,95,96],"oxaliplatin-induced peripheral neuropathy","Peripheral Neuropathy","Oxaliplatin","Body Mass Index (BMI)","Sarcopenia","2025-12-02",{"date":99,"type":100},"2025-12-16","ACTUAL",{"date":102,"type":100},"2025-10-06",{"date":104,"type":83},"2026-09-18",{"name":5,"class":6},1]