[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564436":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":10,"responsibleParty":26,"collaborators":10,"id":30,"slug":31,"hasResults":32,"nctId":33,"briefTitle":34,"officialTitle":35,"acronym":36,"eligibilityCriteria":37,"healthyVolunteers":32,"sex":38,"minAge":39,"maxAge":10,"enrollmentInfo":40,"targetDuration":10,"studyType":43,"phases":10,"briefSummary":44,"conditions":45,"keywords":48,"overallStatus":51,"whyStopped":10,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":10},{"fullName":5,"class":6},"Universitair Ziekenhuis Brussel","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"People with multiple sclerosis",null,"This study will include 50 people with MS (see in\u002Fexclusion criteria under \"Eligibility\").",[13],"Diagnostic Test: Infrared oculography",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Infrared oculography","Eye movements will be captured through infrared oculography and processed via in-house algorithms.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Jeroen Van Schependom, PhD in Medical Sciences","CONTACT","0032 6291040","jeroen.van.schependom@vub.be",{"type":27,"investigatorFullName":28,"investigatorTitle":29,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Jeroen Van Schependom","Research Professor","100564436","studying-eye-movement-deficits-and-cognitive-impairment-in-patients-with-multiple-sclerosis-using-infrared-eye-tracking-and-cognitive-tests-100564436",false,"NCT06629155","Studying Eye Movement Deficits and Cognitive Impairment in Patients with Multiple Sclerosis Using Infrared Eye Tracking and Cognitive Tests","Disentangling Cognitive Functioning and Visual Scanning Deficits in Cognitive Test Results in Multiple Sclerosis (MS)","VisuMS","Inclusion criteria:\n\n* Diagnosed with clinically definite multiple sclerosis according to the 2017 McDonald criteria\n* At least 18 years old\n* Combined vision with optimal correction \\> 0,6 on Snellen Visual Acuity Test.\n* Providing informed consent.\n\nExclusion criteria:\n\n* Major medical or psychiatric pathology that potentially affects cognitive functioning.\n* A score higher than 63 on the Fatigue Scale for Motor and Cognitive Functions is categorized as severe fatigue\n* Start or switch in immunomodulatory treatment within three months before inclusion.\n* Less than 3 months post exacerbation.\n* Refusing informed consent.","ALL","18 Years",{"count":41,"type":42},50,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to study the relationship between cognitive problems and problems in eye movements in Multiple Sclerosis (MS).\n\nThe main questions it aims to answer are:\n\n* What is the correlation between eye movement parameters (VDI AUC and VDI Pv\u002FAm, left and right) and SDMT scores in patients with MS?\n* What is the number of patients with VDI AUC\\>1.174 and\u002For VDI Pv\u002FAm\\>1.180 assessed by infrared oculography during prosaccades at 15 degrees left or right?\n* What is the correlation between eye movement parameters (VDI AUC and VDI Pv\u002FAm, left and right) and cognitive test scores in patients with MS?\n\nParticipants will perform specific cognitive tests and eye movements will be measured through infrared oculography.\n\nThe primary hypothesis for the study is: participants who exceed the treshold (VDI AUC\\>1.174 and\u002For VDI Pv\u002FAm\\>1.180, left or right) will perform worse on cognitive tests compared to those who don't.",[46,47],"Multiple Sclerosis","Internuclear Ophthalmoplegia",[49,46,47,50],"Cognitive impairment","SDMT","NOT_YET_RECRUITING","2024-11-04",{"date":54,"type":55},"2024-11-06","ACTUAL",{"date":57,"type":42},"2025-03-01",{"date":59,"type":42},"2027-02-01",{"name":5,"class":6}]