[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100544966":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":61,"collaborators":25,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":25,"eligibilityCriteria":68,"healthyVolunteers":65,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Xuanwu Hospital, Beijing","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Subarachnoid-Subarachnoid (S-S) Bypass","EXPERIMENTAL","After dissections of the normal arachnoid mater at the cephalic and caudal sites, 1 or 2 tubes made of medical grade silicone (ventricular drainage tube; internal diameter 1.5-2.0 mm, external diameter 2.5-3.3 mm) were inserted into the cephalic and caudal ends of the normal subarachnoid space. The part of the tube inserted into the subarachnoid space was approximately 2 cm long. The total length of the tube was equal to the distance between the cephalic and caudal ends of the normal dissected arachnoid mater, along with approximately 4 cm of extra tubing.",[13],"Procedure: Subarachnoid-Subarachnoid (S-S) Bypass",{"label":15,"type":16,"description":17,"interventionNames":18},"Intradural Adhesion Lysis","ACTIVE_COMPARATOR","The dura is opened sharply, exposing the spinal cord. After microsurgical dissection adhesion, the dura is sewn closed with a dural graft.",[19],"Procedure: Intradural Adhesion Lysis",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","The dura was widely exposed beyond the level of trauma, and then a midline dural opening was made under an operative microscope. When dura and arachnoid were adhered because of an expansion of arachnoiditis, they had to be released with great care to place the bypass tubes. During this procedure, S-S bypass was not usually needed to performed arachnoid lysis. This exposure had to reach the normal arachnoid mater free from arachnoiditis and adhesion, with normal CSF circulation.\n\nAfter dissections of the normal arachnoid mater at the cephalic and caudal sites, 1 or 2 tubes made of medical grade silicone (ventricular drainage tube; internal diameter 1.5-2.0 mm, external diameter 2.5-3.3 mm) were inserted into the cephalic and caudal ends of the normal subarachnoid space. The part of the tube inserted into the subarachnoid space was approximately 2 cm long.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Intradural spinal cord Adhesion Lysis",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"fengzeng jian","CONTACT","01083198899","jianfengzeng@xwh.ccmu.edu.cn",{"name":36,"role":32,"phone":33,"phoneExt":25,"email":37},"yuan chenghua","yuanchenghua@ccmu.edu.cn",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Fengzeng Jian","RECRUITING","Beijing","Beijing Municipality","100053","China","CN",{"type":48,"coordinates":49},"Point",[50,51],116.39723,39.9075,{"lat":51,"lon":50},[54,56,58],{"name":55,"role":32,"phone":25,"phoneExt":25,"email":37},"Yuan Chenghua",{"name":57,"role":32,"phone":25,"phoneExt":25,"email":34},"Jian Fengzeng",{"name":59,"role":60,"phone":25,"phoneExt":25,"email":25},"jian guan, dr","SUB_INVESTIGATOR",{"type":62,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100544966","subarachnoid-subarachnoid-s-s-bypass-versus-adhesion-lysis-in-spinal-arachnoiditis-and-syringomyelia-100544966",false,"NCT06375759","Subarachnoid-Subarachnoid (S-S) Bypass Versus Adhesion Lysis in Spinal Arachnoiditis and Syringomyelia","Inclusion Criteria:\n\n* 1\\) history of traumatic spinal cord injury or other infection; 2) evidence of progressive neurological deficit, and\u002For pain syndrome; 3) MRI showing a syringomyelia due to spinal trauma or other infection; and 4) minimum follow-up period of more than 1 year.\n\nExclusion Criteria:\n\n* Chiari-malformation, myelomalacia, subarachnoid cyst, syringomyelia due to other spinal diseases (such as degenerative spinal disease)","ALL","18 Years","80 Years",{"count":73,"type":74},200,"ESTIMATED","INTERVENTIONAL",[77],"NA","To determine whether Subarachnoid-Subarachnoid (S-S) Bypass results in better patient outcomes with fewer complications and improved quality of life compared to intradural adhesion lysis in individuals with Spinal Arachnoiditis and Syringomyelia.",[80],"Syringomyelia",[82],"syringomyelia","2024-04-16",{"date":85,"type":86},"2024-04-19","ACTUAL",{"date":88,"type":74},"2024-04",{"date":90,"type":74},"2027-04",{"name":5,"class":6},1]