[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634878":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":14,"collaborators":7,"id":18,"slug":19,"hasResults":20,"nctId":21,"briefTitle":22,"officialTitle":23,"acronym":7,"eligibilityCriteria":24,"healthyVolunteers":20,"sex":25,"minAge":26,"maxAge":27,"enrollmentInfo":28,"targetDuration":7,"studyType":31,"phases":7,"briefSummary":32,"conditions":33,"keywords":7,"overallStatus":35,"whyStopped":7,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":7},{"fullName":5,"class":6},"Assiut University","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Kerolos Atef Thabet","CONTACT","01211014182","keroloseatef11@gmail.com",{"type":15,"investigatorFullName":16,"investigatorTitle":17,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Kerolos atef thabet mosaad","Doctor","100634878","subclinical-atherosclerosis-in-juvenile-systemic-lupus-erythematosus-100634878",false,"NCT07545408","Subclinical Atherosclerosis in Juvenile Systemic Lupus Erythematosus","Subclinical Atherosclerosis in Juvenile Systemic Lupus Erythematosus: Evaluation by Carotid Intima-Media Thickness and Associated Cardiovascular Risk Factors","Inclusion Criteria:\n\n\\- Children and adolescents aged under 18 years diagnosed with JSLE according to the Systemic Lupus International Collaborating Clinics ( SLICC 2012 Criteria ).\n\nDisease duration of at least 6 months.\n\nUnder regular follow-up at the study institution.\n\nExclusion Criteria:\n\n* Patients with other autoimmune or connective tissue overlap diseases (e.g., mixed connective tissue disease, juvenile dermatomyositis).\n\nPatients with congenital heart disease or known structural cardiovascular abnormalities.\n\nPatients with chronic kidney disease stage 4 or 5.\n\nPatients currently receiving lipid-lowering therapy prior to enrolment","ALL","0 Years","18 Years",{"count":29,"type":30},70,"ESTIMATED","OBSERVATIONAL","The aim of this study is to evaluate subclinical atherosclerosis in children and adolescents with juvenile SLE by measuring carotid intima-media thickness (CIMT), and to determine its associations with traditional cardiovascular risk factors (dyslipidemia, hypertension, obesity) and non-traditional disease-related risk factors (disease activity, lupus nephritis, corticosteroid dose, disease duration).",[34],"Atherosclerosis","NOT_YET_RECRUITING","2026-04-16",{"date":38,"type":39},"2026-04-22","ACTUAL",{"date":41,"type":30},"2026-06-01",{"date":43,"type":30},"2027-08-01",{"name":5,"class":6}]