[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634198":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":58,"collaborators":25,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":25,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":25,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":25,"overallStatus":37,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Caffeine group","EXPERIMENTAL","Patients will receive sublingual caffeine at the end of surgery.",[13],"Drug: Caffine citrate",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo group","PLACEBO_COMPARATOR","Patients will receive sublingual placebo at the end of surgery.",[19],"Other: Placebo",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DRUG","Caffine citrate",[9],null,{"type":6,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Placebo",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Ghada A Sherif, MD","CONTACT","00201006153615","drghadasherif@gmail.com",[36],{"facility":5,"status":37,"city":38,"state":25,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Cairo","12613","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.24967,30.06263,{"lat":46,"lon":45},[49,50,53,56],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":51,"role":52,"phone":25,"phoneExt":25,"email":25},"Ahmed Z Emam, MBBCH","PRINCIPAL_INVESTIGATOR",{"name":54,"role":55,"phone":25,"phoneExt":25,"email":25},"Ahmed A Badawy, MD","SUB_INVESTIGATOR",{"name":57,"role":55,"phone":25,"phoneExt":25,"email":25},"Ahmed F Mohamed, MD",{"type":52,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Ghada AboBakr Mohamed Sherif","Lecturer of Anesthesiology, Surgical Intensive Care and Pain Management, Faculty of Medicine - Cairo University","100634198","sublingual-caffeine-on-reducing-recovery-time-and-postoperative-agitation-in-elderly-patients-undergoing-general-anesthesia-100634198",false,"NCT07536568","Sublingual Caffeine on Reducing Recovery Time and Postoperative Agitation in Elderly Patients Undergoing General Anesthesia","Efficacy of Sublingual Caffeine on Reducing Recovery Time and Postoperative Agitation in Elderly Patients Undergoing General Anesthesia: A Double-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥ 65 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status II.\n* Scheduled for elective ophthalmology surgery under general anesthesia.\n\nExclusion Criteria:\n\n* History of severe cardiac arrhythmias or uncontrolled hypertension.\n* ASA III patients were excluded to reduce the risk of adverse events in elderly patients with severe systemic diseases.\n* Known allergy or hypersensitivity to caffeine.\n* Pre-existing cognitive impairment or dementia (All patients will undergo preoperative cognitive screening using the online Mini-Cog test or Montreal Cognitive Assessment \\[MoCA\\]).\n* History of seizures or epilepsy.\n* History of alcohol or drug abuse.\n* Chronic use of CNS stimulants or sedatives.\n* Emergency surgeries.\n* Prolonged procedures for more than 3 hours.","ALL","65 Years",{"count":71,"type":72},50,"ESTIMATED","INTERVENTIONAL",[75],"NA","This study aims to evaluate the efficacy of sublingual caffeine in reducing recovery time and incidence of postoperative agitation in elderly patients undergoing general anesthesia.",[78,79,80,81,82,83],"Sublingual","Caffeine","Recovery Time","Postoperative Agitation","Elderly Patients","General Anesthesia","2026-04-18",{"date":86,"type":87},"2026-04-21","ACTUAL",{"date":84,"type":87},{"date":90,"type":72},"2026-08-30",{"name":5,"class":6},1]