[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644783":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":43,"responsibleParty":60,"collaborators":62,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":68,"sex":73,"minAge":74,"maxAge":26,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":86,"overallStatus":88,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Boston Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"ACT Therapy","EXPERIMENTAL","Participants randomized to this group will receive the ACT intervention",[13],"Behavioral: Acceptance and Commitment Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Attention Control","ACTIVE_COMPARATOR","Participants in the control group will receive minimally enhanced usual care to receive treatment as usual enhanced by a health information group session.",[19],"Behavioral: Attention Control",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Acceptance and Commitment Therapy","The ACT group intervention will involve a mixture of didactic instruction, discussion, and experiential activities. ACT will help internally displaced persons to manage stress and prevent or reduce substance use behaviors, ultimately mitigating the onset of substance use disorders.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"Usual care will be minimally enhanced by providing participants with an educational information session that provides information on health promotion.",[15],[31],{"name":32,"affiliation":33,"role":34},"Karsten Lunze, MD DrPH MPH","Boston University Chobanian & Avedisian School of Medicine","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","617-414-6933","lunze@bu.edu",{"name":41,"role":37,"phone":26,"phoneExt":26,"email":42},"Kimberly Hook, PhD MA","kmhook@hsph.harvard.edu",[44],{"facility":45,"status":26,"city":46,"state":26,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Alliance for Public Health","Kyiv","Ukraine","UA",{"type":50,"coordinates":51},"Point",[52,53],30.5238,50.45466,{"lat":53,"lon":52},[56],{"name":57,"role":37,"phone":58,"phoneExt":26,"email":59},"Pavlo Smyrnov","+380 44 490-5485","Smyrnov@aph.org.ua",{"type":61,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[63],{"name":64,"class":65},"National Institute on Drug Abuse (NIDA)","NIH","100644783","substance-use-prevention-for-recently-displaced-adults---supra-r33-rct-100644783",false,"NCT07672457","Substance Use Prevention for Recently Displaced Adults - SUPRA (R33) RCT","SUPRA RCT R33","Inclusion Criteria:\n\n1. Age 18 or over\n2. Have been displaced at least once due to Anti-Terrorist Operation (ATO) or full-scale invasion since 2014\n3. Self-reported use of at least one substance other than alcohol and tobacco within the past 3 months\n4. Ability to provide informed consent and speak Ukrainian or Russian\n\nExclusion Criteria:\n\n1. Self-reported diagnosis of a substance use disorder\n2. Inability to provide informed consent","ALL","18 Years",{"count":76,"type":77},144,"ESTIMATED","INTERVENTIONAL",[80],"NA","This study is a randomized controlled trial among 144 internally displaced people to determine the feasibility, acceptability, and preliminary effectiveness of a single-session Acceptance of Commitment Therapy (ACT) group therapy on preventing or reducing substance use behaviors.",[83,84,85],"Prevention","Substance Use","Refugee Health",[87,47,84],"Displacement","NOT_YET_RECRUITING","2026-06-23",{"date":91,"type":92},"2026-06-29","ACTUAL",{"date":94,"type":77},"2027-04",{"date":96,"type":77},"2028-12",{"name":5,"class":6},1]