[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594427":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":49,"locations":55,"responsibleParty":74,"collaborators":36,"id":78,"slug":79,"hasResults":80,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":36,"eligibilityCriteria":84,"healthyVolunteers":80,"sex":85,"minAge":86,"maxAge":36,"enrollmentInfo":87,"targetDuration":36,"studyType":90,"phases":91,"briefSummary":93,"conditions":94,"keywords":99,"overallStatus":58,"whyStopped":36,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"University of Siena","OTHER",[8,15,20,26],{"label":9,"type":10,"description":11,"interventionNames":12},"AH Plus + Continuous Wave Condensation","ACTIVE_COMPARATOR","Root canal obturation using AH Plus (Dentsply Sirona, Charlotte, NC, USA) and the continuous wave technique with thermoplasticized gutta-percha",[13,14],"Procedure: AH Plus (Dentsply Sirona, Charlotte, NC, USA)","Procedure: Continuous Wave Condensation",{"label":16,"type":10,"description":17,"interventionNames":18},"AH Plus + Single Cone","Root canal obturation using AH Plus and the single cone technique with cold gutta-percha.",[13,19],"Procedure: Single Cone Technique",{"label":21,"type":22,"description":23,"interventionNames":24},"NeoSealer Flo + Continuous Wave","EXPERIMENTAL","Root canal obturation using NeoSealer Flo (Avalon Biomed, Houston, TX, USA) and the continuous wave technique.",[25,14],"Procedure: NeoSealer Flo",{"label":27,"type":22,"description":28,"interventionNames":29},"NeoSealer Flo + Single Cone","Root canal obturation using NeoSealer Flo and the single cone technique.",[25,19],[31,37,41,45],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"PROCEDURE","AH Plus (Dentsply Sirona, Charlotte, NC, USA)","Root canal obturation using AH Plus (Dentsply Sirona, Charlotte, NC, USA), a resin-based sealer with low solubility and shrinkage. Used in combination with gutta-percha for root canal filling.",[9,16],null,{"type":32,"name":38,"description":39,"armGroupLabels":40,"otherNames":36},"NeoSealer Flo","Root canal obturation using NeoSealer Flo (Avalon Biomed, Houston, TX, USA), a premixed bioceramic sealer based on calcium silicate. Used in combination with gutta-percha to enhance apical healing and biocompatibility.",[21,27],{"type":32,"name":42,"description":43,"armGroupLabels":44,"otherNames":36},"Continuous Wave Condensation","A warm vertical compaction technique using heat-softened gutta-percha to obturate the canal in three dimensions. Considered the gold standard for achieving dense and homogenous root canal fillings.",[9,21],{"type":32,"name":46,"description":47,"armGroupLabels":48,"otherNames":36},"Single Cone Technique","A cold hydraulic condensation technique using a single gutta-percha cone matched to the last rotary file, combined with a high-flow sealer. Designed for simplified obturation with minimal operator variability.",[16,27],[50],{"name":51,"role":52,"phone":53,"phoneExt":36,"email":54},"Giulia Malvicini, DDS","CONTACT","+ 39 3487200168","giulia.malvicini@student.unisi.it",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":60,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"Universidad Rey Juan Carlos","RECRUITING","Madrid","Spain","28922","ES",{"type":64,"coordinates":65},"Point",[66,67],-3.70256,40.4165,{"lat":67,"lon":66},[70],{"name":71,"role":52,"phone":72,"phoneExt":36,"email":73},"José Aranguren, DDS","Spain: +34 617352993","josearanguren@hotmail.com",{"type":75,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Simone Grandini","Prof","100594427","success-of-endodontic-treatment-with-different-obturation-techniques-and-sealer-cements-100594427",false,"NCT07019298","Success of Endodontic Treatment With Different Obturation Techniques and Sealer Cements","Evaluation of the Success Rate of Endodontic Treatment Using Different Obturation Techniques and Root Canal Sealer Cements: A Randomized Controlled Trial","Inclusion Criteria:\n\nPatients aged 18 years and older. Teeth with a diagnosis of pulpal necrosis or irreversible pulpitis. Informed consent provided for data usage.\n\nExclusion Criteria:\n\n* Patients with systemic conditions that may impair healing (e.g., uncontrolled diabetes, immunosuppression).\n* Teeth with root fractures, resorption, or open apices.\n* Incomplete clinical or radiographic records.\n* Cases with poor-quality radiographs or lack of standardization for evaluation","ALL","18 Years",{"count":88,"type":89},270,"ESTIMATED","INTERVENTIONAL",[92],"NA","The present study aims to compare the radiographic success of endodontic treatment using Orstavik's criteria between two sealers: AH Plus (Dentsply DeTrey, Konstanz, Germany) and Neosealer Flo (Avalon Biomed, Bradenton, Florida, USA), as well as between two obturation techniques: continuous wave and single cone. The study includes 270 patients, with a minimum follow-up period of 6 months. Clinical and radiographic variables will be assessed, including quality of obturation, lesion healing, and restoration. The study seeks to determine if the use of bioceramic sealer is effective regardless of the obturation technique used, highlighting the importance of clinical follow-up to evaluate endodontic treatment success.",[95,96,97,98],"Pulpitis","Periapical Lesions","Periapical Periodontitis","Periapical Pathology",[100,101,102,103],"Endodontics","Endodontic Sealer","Calcium Silicate-Based Sealer","Ah Plus","2025-06-04",{"date":106,"type":107},"2025-06-13","ACTUAL",{"date":109,"type":107},"2025-06-01",{"date":111,"type":89},"2029-06-01",{"name":5,"class":6},1]