[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616745":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":56,"collaborators":11,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":11,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Region Skane","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Meal intake","EXPERIMENTAL",null,[13],"Dietary Supplement: Meal load",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DIETARY_SUPPLEMENT","Meal load","Meal load during 15 minutes",[9],[21],{"name":22,"affiliation":23,"role":24},"Cecilia Kennbäck, Registered Nurse","Department of Internal Medicine, Skåne University Hospital, 20502 Malmö","STUDY_CHAIR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":11,"email":30},"Bodil Ohlsson C Professor, MD, PhD","CONTACT","+46+402712660","bodil.ohlsson@med.lu.se",{"name":32,"role":28,"phone":11,"phoneExt":11,"email":33},"Mauro D'Amato Professor","mdamato@cicbiogune.es",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Skåne University Hospital","RECRUITING","Malmö","Skåne County","20502","Sweden","SE",{"type":44,"coordinates":45},"Point",[46,47],13.00073,55.60587,{"lat":47,"lon":46},[50,53],{"name":51,"role":28,"phone":52,"phoneExt":11,"email":30},"Bodil Ohlsson, Professor, MD, PhD","+46402712660",{"name":54,"role":28,"phone":11,"phoneExt":11,"email":55},"Cecilia Kennbäck, Nurse","cecilia.kennback@skane.se",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Bodil Ohlsson","Professor","100616745","sucrase-isomaltase-si-genes-and-meal-load-100616745",false,"NCT07309601","Sucrase-Isomaltase (SI) Genes and Meal Load","Comparison of a Meal Load Between Normal and Functional Variants of the Sucrase-isomaltase (SI) Gene in IBS","SI IBS","Inclusion Criteria:\n\n* Diagnosis of irritable bowel syndrome (IBS)\n* Gene testing has been conducted regarding genes regulating the production of sucrase-isomaltase ensymes in previous dietary interventions using the starch- and sucrose reduced diet (SSRD) or multi-center study.\n\nExclusion Criteria:\n\n* Diagnosis of inflammatory bowel disease, celiac disease, bile salt malabsorption, gastroenteritis or enteric dysmotility\n* Severe food allergy\n* Serious heart-, lung-, cardiovascular-, malignant- or mental illness\n* Ongoing eating disorder\n* Pregnancy\n* Recent major gastrointestinal surgery\n* Alcohol and\u002For drug addiction","ALL","18 Years","70 Years",{"count":72,"type":73},70,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this interventional study is to examine whether those patients with irritable bowel syndrome (IBS) and a reduced abitility do degrade starch and sugar (lowe levels of enzymes) have lower raise in blood glucose after a meal than those with normal expression of enzymes. We also want to examine whether those IBS patients with reduced enzyme levels have increased bowel symptom in relation to this meal.\n\nThe main questions it aims to answer are:\n\nDoes reduced ability to degrade starch and sugar due to less enzyme activity lead to lower increase in blood glucose after a meal? Does reduced ability to degrade starch and sugar due to less enzyme activity lead to increased bowel symptoms after a meal?",[79,80],"IBS - Irritable Bowel Syndrome","Sucrase-Isomaltase Deficiency",[82,83,84,85,86],"IBS","SI genes","Starch and sucrose","blood glucose levels","bowel symptoms","2026-04-28",{"date":89,"type":90},"2026-04-29","ACTUAL",{"date":92,"type":90},"2026-02-01",{"date":94,"type":73},"2030-02-01",{"name":5,"class":6},1]