[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587688":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":114,"collaborators":25,"id":117,"slug":118,"hasResults":119,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":25,"eligibilityCriteria":123,"healthyVolunteers":119,"sex":124,"minAge":125,"maxAge":126,"enrollmentInfo":127,"targetDuration":25,"studyType":130,"phases":131,"briefSummary":133,"conditions":134,"keywords":139,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":143,"lastUpdatePostDateStruct":144,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":152},{"fullName":5,"class":6},"Karolinska Institutet","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Safe Alternatives for Teens and Youth (SAFETY)","EXPERIMENTAL","SAFETY is a transdiagnostic cognitive-behavioral family treatment informed by Dialectical Behavior Therapy (DBT) and Multisystemic Therapy (MST). The twelve week long treatment is principle based, structured in phases, and individually tailored based on a cognitive-behavioral fit analysis that specifies key risk and protective processes. Each session contains one individual component for youth and parents respectively, and one family component where youth and parents work together with therapists to practice skills identified as critical for preventing future suicidal behavior. Treatment targets are arranged in a SAFETY Pyramid, consisting of (a) safe settings; (b) safe people; (c) safe activities and actions; (d) safe thought; and (e) safe stress reactions, emphasizing strengthening protective support and validation within the family and\u002For social environment surrounding the youth.",[13],"Behavioral: Safe Alternatives for Teens and Youth (SAFETY)",{"label":15,"type":16,"description":17,"interventionNames":18},"Enhanced Treatment As Usual","ACTIVE_COMPARATOR","Enhanced Treatment As Usual (ETAU) consists of treatment as usual delivered by community clinicians enhanced by the evidence-informed Stanley-Brown Safety Planning Intervention, adapted for adolescents (e.g. involving both youth and parents) and to a Swedish context by the Swedish Association for Child and Adolescent Psychiatry and supervised by the research group. The adapted Safety Planning intervention include an assessment of current and future risk and protective factors for suicide, current and future suicide risk, and an individualized safety plan. We will ensure that the control intervention Safety Planning is delivered in a safe and comparable way across regions. Patients in both conditions will have access to standard care (including pharmaceutical treatment), as well as inpatient care as deemed necessary. The level of standard care will be carefully measured throughout the trial and included in statistical sensitivity analyses.",[19],"Behavioral: Enhanced Treatment As Usual",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Please see description of experimental arm (arm one)",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Please see description of active comparator arm (arm two).",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Lydia Peraza Aguiar, MSc","CONTACT","+46735170963","lydia.peraza.aguiar@ki.se",{"name":36,"role":32,"phone":37,"phoneExt":25,"email":38},"Moa Karemyr, MSc","+46723950443","moa.karemyr@ki.se",[40,59,73,87,101],{"facility":41,"status":42,"city":43,"state":25,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Child and Adolescent Mental Health Services, Region Skåne","RECRUITING","Helsingborg","25225","Sweden","SE",{"type":48,"coordinates":49},"Point",[50,51],12.69437,56.04673,{"lat":51,"lon":50},[54,57],{"name":55,"role":32,"phone":25,"phoneExt":25,"email":56},"Eva Serlachius, MD, PhD","eva.serlachius@med.lu.se",{"name":55,"role":58,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"facility":60,"status":61,"city":62,"state":25,"zip":25,"country":45,"countryCode":46,"cosmosGeoPoint":63,"geoPoint":67,"contacts":68},"Child and Adolescent Psychiatry, Region Värmland","NOT_YET_RECRUITING","Karlstad",{"type":48,"coordinates":64},[65,66],13.50357,59.3793,{"lat":66,"lon":65},[69,72],{"name":70,"role":32,"phone":25,"phoneExt":25,"email":71},"Maria Unenge Hallerbäck, MD, Ph.D.","maria.unenge.hallerback@regionvarmland.se",{"name":70,"role":58,"phone":25,"phoneExt":25,"email":25},{"facility":74,"status":42,"city":75,"state":25,"zip":76,"country":45,"countryCode":46,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Child and Adolescent Mental Health Services, Region Halland","Kungsbacka","301 85",{"type":48,"coordinates":78},[79,80],12.07612,57.48719,{"lat":80,"lon":79},[83,86],{"name":84,"role":32,"phone":25,"phoneExt":25,"email":85},"Anna Santesson, MD, PhD","anna.santesson@regionhalland.se",{"name":84,"role":58,"phone":25,"phoneExt":25,"email":25},{"facility":88,"status":42,"city":89,"state":25,"zip":90,"country":45,"countryCode":46,"cosmosGeoPoint":91,"geoPoint":95,"contacts":96},"Child and Adolescent Mental Health Services, Region Stockholm","Stockholm","118 51",{"type":48,"coordinates":92},[93,94],18.06871,59.32938,{"lat":94,"lon":93},[97,100],{"name":98,"role":32,"phone":25,"phoneExt":25,"email":99},"Anna Ohlis, MD, PhD","anna.ohlis@ki.se",{"name":98,"role":58,"phone":25,"phoneExt":25,"email":25},{"facility":102,"status":42,"city":103,"state":25,"zip":25,"country":45,"countryCode":46,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"Child and Adolescent Psychiatry, Region Uppsala","Uppsala",{"type":48,"coordinates":105},[106,107],17.63889,59.85882,{"lat":107,"lon":106},[110,113],{"name":111,"role":32,"phone":25,"phoneExt":25,"email":112},"Mia Ramklint, MD, PhD","mia.ramklint@uu.se",{"name":111,"role":58,"phone":25,"phoneExt":25,"email":25},{"type":58,"investigatorFullName":115,"investigatorTitle":116,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Johan Bjureberg","Associate Professor","100587688","suicide-preventive-psychosocial-treatment-for-youths-100587688",false,"NCT06931639","Suicide Preventive Psychosocial Treatment for Youths","Suicide Preventive Psychosocial Treatment for Youths: A Randomized Controlled Trial","Inclusions criteria:\n\n1. Suicide attempt in the last 3 months\n2. Age 10-17 years\n3. At least one primary caregiver (multiple is allowed) willing to participate in treatment\n\nExclusion criteria:\n\n1. Symptoms obstructing participation in assessments or treatment\n2. Insufficient understanding of the Swedish language in youth and\u002For caregiver\n3. Enrolled in Dialectical Behavioral Therapy","ALL","10 Years","17 Years",{"count":128,"type":129},282,"ESTIMATED","INTERVENTIONAL",[132],"NA","Suicide is the leading cause of death amongst 10-18-year-olds in Sweden. Suicide attempts are the strongest predictor of subsequent death by suicide, often lead to inpatient care, and are associated with substantial societal costs, making suicide attempts a critical target in psychiatric intervention research. Although youths attempting suicide are typically assessed and treated for potential comorbid psychiatric conditions, there is currently no trans-diagnostic evidence-based treatment specifically targeting suicidal behavior. To fill this gap, the Safe Alternatives for Teens and Youths (SAFETY) was developed. SAFETY is a transdiagnostic family-based cognitive-behavioral suicide prevention program that has shown promise but more studies are needed.\n\nThe overall objective of this project is to evaluate the efficacy, durability, and cost-effectiveness of the SAFETY intervention, a scalable suicide prevention intervention that can be offered immediately following a youth suicide attempt, in a fully powered single-blind randomized controlled superiority trial. Our primary hypothesis is that the SAFETY intervention will be superior to Enhanced Treatment As Usual (enhanced with the evidence-based intervention safety planning) in reducing the proportion of suicide reattempts. Moreover, we predict that these improvements will be maintained for up to 60 months post-treatment. Finally, we expect that SAFETY will be cost-effective compared to the control intervention, both at the primary endpoint and in the longer term.",[135,136,137,138],"Suicide Attempt","Suicidal and Self-injurious Behavior","Suicide Attempted","Suicide, Attempted",[140,141,135,142],"Safe Alternatives for Teens and Youths","Self-injurious Behavior","Suicidal Behavior","2026-04-14",{"date":145,"type":146},"2026-04-17","ACTUAL",{"date":148,"type":146},"2025-05-28",{"date":150,"type":129},"2032-09",{"name":5,"class":6},5]