[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644988":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":23,"centralContacts":34,"locations":42,"responsibleParty":70,"collaborators":23,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":75,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":23,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":94,"overallStatus":107,"whyStopped":23,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"National Cancer Institute, Egypt","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Group S: Stellate Ganglion super-voltage pulsed radiofrequency","ACTIVE_COMPARATOR","Super-voltage pulsed radiofrequency (PRF) of the stellate ganglion was performed under strict aseptic precautions with standard monitoring. Patients were positioned supine with a slight extension of the neck and head turned contralaterally. Ultrasound guidance using a high-frequency linear transducer was employed to identify the stellate ganglion region at the level of the C6 transverse process, anterior to the longus colli muscle and medial to the carotid sheath. A 22-gauge radiofrequency cannula (5-10 cm length, 5-mm active tip) was advanced using an in-plane technique until the needle tip was positioned adjacent to the sympathetic chain on the surface of the longus colli muscle. After negative aspiration, sensory (50 Hz) and motor (2 Hz) stimulation were performed to confirm appropriate needle placement and exclude somatic nerve involvement.",[13],"Procedure: Group S : Stellate Ganglion supervoltage pulsed radiofrequency",{"label":15,"type":10,"description":16,"interventionNames":17},"Group T: T2-T3 chains supervoltage pulsed radiofrequency","Position the patient prone with bolsters to minimize lordosis and allow C- arm AP and oblique imaging. Under sterile conditions use fluoroscopy to identify T2 and T3 pedicles, ribs and transverse processes. A posterior paravertebral (transforaminal-style) approach is commonly used: advance a curved RFA cannula (20-22G, 10-15 cm with 5-10 mm active tip) under fluoroscopic AP and lateral guidance to the anterolateral aspect of the vertebral body or just anterior to the costotransverse junction at the T2 and T3 levels, the expected location of the thoracic sympathetic chain. Confirm needle position with small (0.5-1 mL) contrast injection to exclude intravascular or pleural spread. Perform sensory (50 Hz) and, if applicable, motor (2 Hz) stimulation to exclude intercostal motor\u002Fpleural\u002Fnerve root proximity.",[18],"Procedure: Group T : T2-T3 chains supervoltage pulsed radiofrequency.",{"label":20,"type":21,"description":22,"interventionNames":23},"Group C: Control group on tramadol 150 mg \u002F day and gabapentin 600 mg \u002F day","NO_INTERVENTION","Control group on tramadol 150 mg \u002F day and gabapentin 600 mg \u002F day",null,[25,30],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":23},"PROCEDURE","Group S : Stellate Ganglion supervoltage pulsed radiofrequency","· Super-voltage pulsed radiofrequency (PRF) of the stellate ganglion was performed under strict aseptic precautions with standard monitoring. Patients were positioned supine with a slight extension of the neck and head turned contralaterally. Ultrasound guidance using a high-frequency linear transducer was employed to identify the stellate ganglion region at the level of the C6 transverse process, anterior to the longus colli muscle and medial to the carotid sheath. A 22-gauge radiofrequency cannula (5-10 cm length, 5-mm active tip) was advanced using an in-plane technique until the needle tip was positioned adjacent to the sympathetic chain on the surface of the longus colli muscle. After negative aspiration, sensory (50 Hz) and motor (2 Hz) stimulation were performed to confirm appropriate needle placement and exclude somatic nerve involvement. Pulsed radiofrequency was then delivered using a supervoltage protocol with a pulse width of 20 ms at a frequency of 2 Hz, applied",[9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":23},"Group T : T2-T3 chains supervoltage pulsed radiofrequency.","Position the patient prone with bolsters to minimize lordosis and allow C- arm AP and oblique imaging. Under sterile conditions use fluoroscopy to identify T2 and T3 pedicles, ribs and transverse processes. A posterior paravertebral (transforaminal-style) approach is commonly used: advance a curved RFA cannula (20-22G, 10-15 cm with 5-10 mm active tip) under fluoroscopic AP and lateral guidance to the anterolateral aspect of the vertebral body or just anterior to the costotransverse junction at the T2 and T3 levels, the expected location of the thoracic sympathetic chain. Confirm needle position with small (0.5-1 mL) contrast injection to exclude intravascular or pleural spread. Perform sensory (50 Hz) and, if applicable, motor (2 Hz) stimulation to exclude intercostal motor\u002Fpleural\u002Fnerve root proximity. For supervoltage PRF, deliver radiofrequency with pulse width 20ms at 2 Hz while maintain the electrode tip temperatue less than 42°C for 120-240 seconds at each level",[15],[35,40],{"name":36,"role":37,"phone":38,"phoneExt":23,"email":39},"Ahmed Soliman","CONTACT","00201286979695","ams21787arif@hotmail.com",{"name":41,"role":37,"phone":23,"phoneExt":23,"email":23},"Salah Ismail",[43],{"facility":44,"status":23,"city":45,"state":23,"zip":23,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"National Cancer Institute","Cairo","Egypt","EG",{"type":49,"coordinates":50},"Point",[51,52],31.24967,30.06263,{"lat":52,"lon":51},[55,59,62,64,66,68],{"name":56,"role":37,"phone":57,"phoneExt":23,"email":58},"National Cancer institute Cairo University","0225328286","irb@nci.cu.edu.eg",{"name":60,"role":61,"phone":23,"phoneExt":23,"email":23},"Emad Gerges, prof","SUB_INVESTIGATOR",{"name":41,"role":63,"phone":23,"phoneExt":23,"email":23},"PRINCIPAL_INVESTIGATOR",{"name":65,"role":63,"phone":23,"phoneExt":23,"email":23},"Ahmed Soliman, Ass. Prof",{"name":67,"role":61,"phone":23,"phoneExt":23,"email":23},"Nahla Shehab, Ass. Prof",{"name":69,"role":61,"phone":23,"phoneExt":23,"email":23},"Osama Elbosraty, Lecturer",{"type":63,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Ahmed Mohamed Soliman","Assistant professor of anesthesia and pain management","100644988","super-voltage-prf-of-stellate-ganglion-versus-super-voltage-prf-of-t2-t3-sympathetic-ganglia-in-managing-pmps-100644988",false,"NCT07675096","Super-voltage PRF of Stellate Ganglion Versus Super-voltage PRF of T2 T3 Sympathetic Ganglia in Managing PMPS.","Super-voltage Pulsed Radiofrequency of Stellate Ganglion Versus Super-voltage Pulsed Radiofrequency of T2 T3 Sympathetic Ganglia in Managing Postmastectomy Pain Syndrome.","PMPS PRF","Inclusion Criteria:\n\n* Female patients aged 18-60 years.\n* Patient of class II according to the American society of Anesthesiologists (ASA) physical status classification system.\n* History of unilateral mastectomy for breast cancer.\n* Persistent pain \\>3 months postoperatively.\n* VAS score ≥4 despite pharmacological management.\n* Patients with neuropathic pain who has a score ≥4 by (DN4) questionnaire.\n* Patients on more than 1 antineuropathic drug.\n\nExclusion Criteria:\n\n* Coagulopathy or anticoagulant therapy.\n* Local infection at injection site.\n* History of psychiatric illness or cognitive dysfunction.\n* Previous intervention in the same region (e.g., prior stellate ganglion block or thoracic radiofrequency ablation).\n* Allergy to local anesthetics or contrast agents.","FEMALE","18 Years","60 Years",{"count":85,"type":86},75,"ESTIMATED","INTERVENTIONAL",[89],"NA","The aim of this study is to compare the effectiveness of super-voltage pulsed radiofrequency of stellate ganglion and super-voltage pulsed radiofrequency of T2-T3 sympathetic ganglia in the treatment of postmastectomy pain syndrome.",[92,93],"Post Mastectomy Pain Syndrome","Chronic Pain Following Surgical Procedure for Cancer",[95,96,97,98,99,100,101,102,103,104,105,106],"Analgesics","Opioids","gabapentin","post mastectomy pain syndrome","chronic pain","Radiofrequency","stellate ganglion block","sympathectomy","T2","T3","SV-PRF","super-voltage pulsed radiofrequency","NOT_YET_RECRUITING","2026-06-23",{"date":110,"type":111},"2026-06-30","ACTUAL",{"date":113,"type":86},"2026-07-01",{"date":115,"type":86},"2027-08-30",{"name":5,"class":6},1]