[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625192":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":19,"locations":25,"responsibleParty":42,"collaborators":18,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":18,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":70,"overallStatus":28,"whyStopped":18,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"University of Pennsylvania","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Supraglottic Airway","EXPERIMENTAL","Premature infants who require positive pressure ventilation immediately after birth will receive ventilation through a supraglottic airway used as the primary airway interface during delivery room resuscitation.",[13],"Other: Supraglottic Airway",[15],{"type":6,"name":9,"description":16,"armGroupLabels":17,"otherNames":18},"Use of a supraglottic airway as the primary interface for delivery of positive pressure ventilation during neonatal resuscitation.",[9],null,[20],{"name":21,"role":22,"phone":23,"phoneExt":18,"email":24},"Sura Lee","CONTACT","215-873-9339","sura.lee@pennmedicine.upenn.edu",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Hospital of the University of Pennsylvania","RECRUITING","Philadelphia","Pennsylvania","19104","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-75.16362,39.95238,{"lat":38,"lon":37},[41],{"name":21,"role":22,"phone":23,"phoneExt":18,"email":24},{"type":43,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100625192","supraglottic-airway-for-resuscitation-in-preemies-100625192",false,"NCT07419438","Supraglottic Airway for Resuscitation in Preemies","Supraglottic Airway Interface for Positive Pressure Ventilation During Delivery Room Resuscitation of Premature Infants: A Pilot Feasibility Trial","SUPREEMIE","Inclusion Criteria:\n\n* Gestational age 29 0\u002F7 to 33 6\u002F7 weeks at birth\n* Estimated fetal weight \\>\u002F= 1000 grams at birth\n* Clinical decision to initiate PPV\n* Parental informed consent\n\nExclusion Criteria:\n\n* Major anomalies or aneuploidy\n* Palliative care planned or considered\n* Not resuscitated in the infant resuscitation room","ALL","0 Days","1 Day",{"count":56,"type":57},20,"ESTIMATED","INTERVENTIONAL",[60],"NA","The goal of this single-arm intervention trial is to learn whether using a supraglottic airway (SA) as the primary interface for positive pressure ventilation (PPV) is feasible during delivery room resuscitation of premature infants. This study will be conducted in premature infants born between 29 0\u002F7 and 33 6\u002F7 weeks' gestation who require PPV at birth.\n\nThe main question it aims to answer is: Is it feasible to use a supraglottic airway as the primary interface to provide effective PPV during delivery room resuscitation in 29 0\u002F7 to 33 6\u002F7 weeks' gestation premature infants?\n\nParticipants will (1)Be screened prenatally and have informed consent obtained from the birth parent prior to delivery; (2)Be rescreened for eligibility on the day of delivery before receiving the study intervention; (3)Receive PPV using a supraglottic airway as the primary ventilation interface if resuscitation is required at birth; and (4)Have clinical and procedural data collected during delivery room resuscitation and for up to 24 hours after birth.",[63,64,65,66,67,9,68,69],"Respiratory Failure","Premature Neonates","Delivery Room Resuscitation","Positive Pressure Ventilation","Neonatal Resuscitation","Laryngeal Mask","Laryngeal Mask Airways",[71,72,65,73,74,9,75,69],"Respiratory failure","Premature neonates","Positive pressure ventilation","Neonatal resuscitation","laryngeal mask","2026-04-16",{"date":78,"type":79},"2026-04-17","ACTUAL",{"date":81,"type":79},"2026-03-13",{"date":83,"type":57},"2026-10",{"name":5,"class":6},1]