[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635248":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":26,"locations":10,"responsibleParty":35,"collaborators":37,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":10,"eligibilityCriteria":47,"healthyVolunteers":43,"sex":48,"minAge":10,"maxAge":10,"enrollmentInfo":49,"targetDuration":52,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":61,"overallStatus":72,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":10},{"fullName":5,"class":6},"Vastra Gotaland Region","OTHER_GOV",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"SALSA",null,"Surfactant Administration via Laryngeal or Supraglottic Airway",{"label":13,"type":10,"description":14,"interventionNames":10},"LISA","Less Invasive Surfactant Administration using a thin catheter applied below the vocal cords guided by laryngoscopy",{"label":16,"type":10,"description":17,"interventionNames":10},"INSURE","Intubation-Surfactant-Extubation. Followed by positive pressure ventilation or brief period (\\\u003C1 hour) of mechanical ventilation",{"label":19,"type":10,"description":20,"interventionNames":10},"Group\u002FCohort Description: Intubation-Surfactant-Extubation. Followed by positive pressure ventilatio","Continued on mechanical ventilation \\>1 hour",[22],{"name":23,"affiliation":24,"role":25},"Anders Elfvin, Professor","Department of Neonatology, Queen Silvia Children's Hospital, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden","PRINCIPAL_INVESTIGATOR",[27,31],{"name":23,"role":28,"phone":29,"phoneExt":10,"email":30},"CONTACT","+46313438073","anders.elfvin@vgregion.se",{"name":32,"role":28,"phone":33,"phoneExt":10,"email":34},"Mårten Larsson, M.D","+46704240972","marten.larsson@vgregion.se",{"type":36,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[38],{"name":39,"class":40},"Göteborg University","OTHER","100635248","surfactant-administration-methods-in-preterm-infants-with-rds-a-swedish-cohort-study-100635248",false,"NCT07550218","Surfactant Administration Methods in Preterm Infants With RDS: A Swedish Cohort Study","A Prospective Observational Study of Surfactant AdministrationMethods for Preterm Infants With Respiratory Distress SyndromeWith Long-term Follow-up in the Swedish Neonatal Quality Register","Inclusion Criteria:\n\n* Patient has received surfactant by any administration method\n* Gestational age below 37 weeks'\n* First surfactant treatment given before 48 hours of age\n* Confirmed or suspected diagnosis of respiratory distress syndrome (RDS)\n\nExclusion Criteria:\n\n• Not fulfilling above inclusion criteria","ALL",{"count":50,"type":51},300,"ESTIMATED","6 Years","OBSERVATIONAL","The goal of this observational study is to evaluate different methods of surfactant administration in preterm infants with respiratory distress syndrome (RDS). Preterm infants often have immature lungs and a deficiency of surfactant, a substance that helps keep the lungs open and supports oxygen exchange.Surfactant can be delivered to the lungs using different techniques, including INSURE (brief intubation), LISA (via a thin catheter), SALSA (via a laryngeal mask airway), and traditional administration via endotracheal intubation followed by mechanical ventilation. The main question this study aims to answer is:Which method of surfactant administration is associated with better clinical outcomes in preterm infants with RDS?The study will prospectively collect clinical data on infants receiving surfactant as part of standard care, with long-term follow-up using data from the Swedish Neonatal Quality Register. The results are intended to be used to inform the design of a future randomized multicenter study.",[56,57,58,59,60],"Respiratory Distress Syndrome (& [Hyaline Membrane Disease])","Respiratory Distress Syndrome (Neonatal)","Respiratory Distress Syndrome (RDS)","Respiratory Distress Syndrome of Newborn","Respiratory Distress Syndrome in Premature Infant",[62,63,64,65,66,67,13,16,68,9,69,70,71],"Preterm infants","Premature infants","Surfactant therapy","Supraglottic Airway","Laryngeal Mask Airway","Intubation","Less Invasive Surfactant Therapy","Surfactant via Laryngeal or Supraglottic Airway","RDS","Respiratory Distress Syndrome","NOT_YET_RECRUITING","2026-04-17",{"date":75,"type":76},"2026-04-24","ACTUAL",{"date":78,"type":51},"2026-04-27",{"date":80,"type":51},"2029-08-27",{"name":5,"class":6}]