[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100323488":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":23,"locations":33,"responsibleParty":51,"collaborators":10,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":10,"eligibilityCriteria":61,"healthyVolunteers":57,"sex":62,"minAge":10,"maxAge":10,"enrollmentInfo":63,"targetDuration":10,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Huazhong University of Science and Technology","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"peripheral EBV-DNA load",null,"subjects with high load (\\>1×103 copies\u002Fml）of EBV-DNA copies in peripheral blood.",[13],"Other: peripheral EBV-DNA load",[15],{"type":6,"name":9,"description":16,"armGroupLabels":17,"otherNames":10},"No intervention",[9],[19],{"name":20,"affiliation":21,"role":22},"Jianfeng Zhou, PhD.and MD.","Director of Department of Hematology in Tongji Hospital，HUST","STUDY_CHAIR",[24,30],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"Jin Huang, PhD.and MD.","CONTACT","86-15926444318","86-83663609","hj20130318@163.com",{"name":20,"role":26,"phone":31,"phoneExt":10,"email":32},"86-13627284963","jfzhou@tjh.tjmu.edu.cn",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Tongji hospital, Tongji medical collage of HUST","RECRUITING","Wuhan","Hubei","430000","China","CN",{"type":43,"coordinates":44},"Point",[45,46],114.26667,30.58333,{"lat":46,"lon":45},[49],{"name":50,"role":26,"phone":27,"phoneExt":10,"email":29},"Jin Huang, PHD",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Jianfeng Zhou","Director of Hematology,Tongji Hospital,Tongji Medical College, Huazhong University of Science and Technology","100323488","surveillance-and-tracking-the-outcomes-of-chronic-latent-ebv-infection-100323488",false,"NCT03491605","Surveillance and Tracking the Outcomes of Chronic Latent EBV Infection","Study to Surveil and Track the Outcomes of Chronic Latent EBV Infection Based on Healthy Volunteers Undergoing Routine Inspection","Inclusion Criteria:\n\n1. immunocompetent subjects who was found to have high EBV-DNA load （\\>1×103 copies\u002Fml）in peripheral blood during the physical examination\n2. Willing to be followed up by telephone or face-to-face interview\n\nExclusion Criteria:\n\n1. Subjects with defined immunodeficiency\n2. Subjects who have taken or are going to take immunosuppressive drugs.\n3. Subjects Diagnosed a validated hematopathy\n4. Subjects diagnosis as precancerous lesion or malignant tumor and the life expectancy is less than 1 year.\n5. psychological illness which does not allow subjects to understand the study and participate following his own free will\n6. Pregnant woman\n7. no written informed consent","ALL",{"count":64,"type":65},10000,"ESTIMATED","OBSERVATIONAL","Immunocompetent subjects with high load of Epstein-Barr virus DNA (EBV-DNA) in peripheral blood will be enrolled and prospectively followed up to track the natural histories of the chronic high load of EBV virus. The primary goal of this study is to explore the association of peripheral high load of EBV with the hematological malignancies, and second goal is to investigate the genetic mechanisms of immune escape and tumorigenesis of chronic EBV infection.",[69],"EBV Infection",[71],"chronic EBV infection, hemophagocytic lymphohistiocytosis","2021-02-09",{"date":74,"type":75},"2021-02-10","ACTUAL",{"date":77,"type":75},"2019-07-01",{"date":79,"type":65},"2029-12-31",{"name":5,"class":6},1]