[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523608":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":26,"responsibleParty":47,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":64,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Fudan University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Observation",null,[12],"Procedure: Watchful waiting",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"PROCEDURE","Watchful waiting","Conduct thoracic computed tomography scans every 12 months. The decision regarding surgery is based on the surgeon's evaluation of radiologic follow-up. The reference resection criteria encompass: a) Any lesion that progresses to a tumor diameter larger than 2cm or has CTR greater than 0.25. b) Clinical Tumor, node, metastasis (TNM) stage upstaging.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":24,"email":25},"Haoxuan Wu, Dr.","CONTACT","86-021-64175590","63189","haoxuanwu@hotmail.com",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Fudan University Cancer Center","RECRUITING","Shanghai","Shanghai Municipality","200032","China","CN",{"type":36,"coordinates":37},"Point",[38,39],121.45806,31.22222,{"lat":39,"lon":38},[42],{"name":43,"role":22,"phone":44,"phoneExt":45,"email":46},"Chen Haiquan, MD","+86-21 64175590","1707","hqchen1@yahoo.com",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Haiquan Chen","Director in the Department of Thoracic Surgery, FUSCC","100523608","surveillance-for-multifocal-ggns-100523608",false,"NCT06097910","Surveillance for Multifocal GGNs","Active Surveillance for Patients with Multifocal Ground-glass Nodules: a Prospective, Multi-center, Single-arm Trial (ECTOP-1021)","Inclusion criteria Patients eligible for enrollment in the study are required to meet all the following criteria.\n\n1. Demonstrates the following on thin-section computed tomography (TSCT) scan:\n\n   1. Presence of three or more GGNs (bilateral lesions are permitted).\n   2. All lesions have remained stable without regression or enlargement for at least 3 months.\n   3. The dominant lesion (the lesion with the largest maximum tumor diameter) has a maximum tumor diameter \\>=0.6cm and \\\u003C=2cm.\n   4. CTR \\\u003C=0.25 in all lesions.\n   5. No lymph node with a diameter \\>1cm in the mediastinal view.\n   6. Not adjacent to the pleura in dominant lesion and no sign of pleural retraction in any lesions.\n2. Aged 18-75 years.\n3. Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.\n4. Has not previously undergo any anti-tumor drug or radiation therapy.\n5. Written informed consent.\n\nExclusion criteria Patients will be excluded if they meet any of the following criteria.\n\n1. History of any prior malignancies within the past 5 years.\n2. History of lung surgery.\n3. History of interstitial pneumonia, pulmonary fibrosis or other severe pulmonary diseases.\n4. Presence of severe or uncontrolled diseases that may possibly reduce the 10-year life expectancy.","ALL","18 Years","75 Years",{"count":62,"type":63},370,"ESTIMATED","10 Years","OBSERVATIONAL","This study is a single-arm, multi-center, phase III trial conducted under the Eastern Cooperative Thoracic Oncoloy Project (ECTOP) with the identification number ECTOP-1021. The primary objective of the study is to assess the overall survival of patients with multifocal ground-glass opacities by employing a active surveillance approach rather than opting for surgical resection.",[68,69],"Lung Ground-glass Opacities","Active Surveillance","2025-01-29",{"date":72,"type":73},"2025-01-31","ACTUAL",{"date":75,"type":73},"2023-11-01",{"date":77,"type":63},"2036-11-01",{"name":5,"class":6},1]