[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578502":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":27,"locations":33,"responsibleParty":84,"collaborators":87,"id":94,"slug":95,"hasResults":96,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":10,"eligibilityCriteria":100,"healthyVolunteers":96,"sex":101,"minAge":102,"maxAge":103,"enrollmentInfo":104,"targetDuration":10,"studyType":107,"phases":10,"briefSummary":108,"conditions":109,"keywords":111,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":124},{"fullName":5,"class":6},"KK Women's and Children's Hospital","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"HOPE Cohort (PICU Survivors)",null,"Helping to Optimize Patients' Experiences (HOPE) after Pediatric Critical Illness Cohort Study \\[Sample Size: 240 participants\\]",[13],"Other: This is a non-interventional study.",{"label":15,"type":10,"description":16,"interventionNames":17},"SHACK-S Cohort (Siblings of PICU Survivors)","Singapore Health outcomes After Critical illness in Kids - Siblings (SHACK-S): Experiences and Health Outcomes of Siblings in the first 6 months after PICU discharge of a critically ill child. \\[Sample Size (Quantitative): 164 participants; Sample Size (Qualitative): 20 participants\\]",[13],[19],{"type":20,"name":21,"description":21,"armGroupLabels":22,"otherNames":10},"OTHER","This is a non-interventional study.",[9,15],[24],{"name":25,"affiliation":5,"role":26},"A\u002FProf Lee Jan Hau, MBBS, MRCPCH, MCI","PRINCIPAL_INVESTIGATOR",[28],{"name":29,"role":30,"phone":31,"phoneExt":10,"email":32},"Eric Jia Yong Ong, BSc (Hons)","CONTACT","+65 62255554","eric.ong.j.y@kkh.com.sg",[34,52],{"facility":35,"status":36,"city":37,"state":37,"zip":38,"country":37,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"National University Singapore","RECRUITING","Singapore","119074","SG",{"type":41,"coordinates":42},"Point",[43,44],103.85007,1.28967,{"lat":44,"lon":43},[47,50],{"name":48,"role":30,"phone":10,"phoneExt":10,"email":49},"Dr Fan Lijia, MBBS, MMed, MRCPCH","li_jia_fan@nuhs.edu.sg",{"name":51,"role":26,"phone":10,"phoneExt":10,"email":10},"Lijia Fan, MBBS, MMed, MRCPCH",{"facility":5,"status":36,"city":37,"state":37,"zip":53,"country":37,"countryCode":39,"cosmosGeoPoint":54,"geoPoint":56,"contacts":57},"229899",{"type":41,"coordinates":55},[43,44],{"lat":44,"lon":43},[58,59,60,62,65,67,69,71,73,75,76,78,80,82],{"name":29,"role":30,"phone":10,"phoneExt":10,"email":32},{"name":25,"role":26,"phone":10,"phoneExt":10,"email":10},{"name":61,"role":26,"phone":10,"phoneExt":10,"email":10},"Pei Fen Poh, PhD",{"name":63,"role":64,"phone":10,"phoneExt":10,"email":10},"Christelle Xian-Ting Tan, MBBS, MRCPCH,MMed, FAMS, PGDip","SUB_INVESTIGATOR",{"name":66,"role":64,"phone":10,"phoneExt":10,"email":10},"Joel Kian Boon Lim, MBBS, MRCPCH, MMed (Paeds)",{"name":68,"role":64,"phone":10,"phoneExt":10,"email":10},"Judith Ju-Ming Wong, MBBCh BAO, MRCPCH, MCI",{"name":70,"role":64,"phone":10,"phoneExt":10,"email":10},"Rehena Sultana, MSc",{"name":72,"role":64,"phone":10,"phoneExt":10,"email":10},"Liying Yang, MSc",{"name":74,"role":64,"phone":10,"phoneExt":10,"email":10},"Phey Hong Yang, M.Ed., DPsych (Clinical)",{"name":29,"role":64,"phone":10,"phoneExt":10,"email":10},{"name":77,"role":64,"phone":10,"phoneExt":10,"email":10},"Wen Yi Wan",{"name":79,"role":64,"phone":10,"phoneExt":10,"email":10},"Kathy Chiew Suan Liaw",{"name":81,"role":64,"phone":10,"phoneExt":10,"email":10},"Shi Hua Chan, MBBS, MRCPCH, MMed (Paeds)",{"name":83,"role":64,"phone":10,"phoneExt":10,"email":10},"Chloe Ann Cheang, MBBS",{"type":26,"investigatorFullName":85,"investigatorTitle":86,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Jan Hau Lee","Associate Professor",[88,90,92],{"name":89,"class":20},"National University Hospital, Singapore",{"name":91,"class":20},"Duke-NUS Graduate Medical School",{"name":93,"class":20},"Singapore Clinical Research Institute","100578502","surviving-the-pediatric-intensive-care-unit-picu-100578502",false,"NCT06812130","Surviving the Pediatric Intensive Care Unit (PICU)","Surviving the Pediatric Intensive Care Unit (PICU): Long-term Study to Understand and Improve Outcomes of PICU Survivors and Their Families","Inclusion Criteria:\n\n\\[HOPE Cohort\\]\n\n1. Between 28 days - 16 years of age at PICU admission\n2. Have an expected PICU stay \\> 48 hours\\*\n\n\\[SHACK-S Cohort\\]\n\n1. Healthy children (aged 4 -16 years old) with critically ill sibling between 28 days - 16 years of age at PICU admission\n2. Has a critically ill sibling who has an expected PICU stay \\> 48 hours\n3. Lives in the same household as the critically ill sibling and parents prior to admission\n\nExclusion Criteria:\n\n\\[HOPE Cohort\\]\n\n1. Do-Not-Resuscitate status\n2. Lack of informed consent\n3. Prior enrolment in this study\n\n\\[SHACK-S Cohort\\]\n\n1. Children of critically ill sibling with Do-Not-Resuscitate status\n2. Children with condition listed on paediatric Complex Chronic Conditions (CCC) system Version 3.0 or with neurocognitive\u002Fneurodevelopmental delays or disorders\n3. Previous admission to PICU\n4. Lack of informed consent\n5. Prior enrolment in this study\n\n   * Note: For participating study sites without a dedicated PICU (e.g., sites where patients are managed in a combined ward under High Dependency (HD) or ICU status), PICU stay will be defined as the duration during which the patient is assigned an ICU status. The determination of ICU status will be made at the discretion of the respective site's study team and Site-PI.","ALL","28 Days","16 Years",{"count":105,"type":106},404,"ESTIMATED","OBSERVATIONAL","Improvement in pediatric intensive care unit (PICU) supportive care has led to improvement in clinical outcomes and decreased mortality in pediatric critical illness. However, PICU survivors are at risk of long-term health sequalae. Given the increased recognition of physical, cognitive, and psychological sequelae in PICU survivors, the concept of post-intensive care syndrome-pediatrics (PICS-p) has been proposed. Besides the PICU patient\u002Fsurvivor, the PICS-p framework also highlights the impacts of a child's critical illness has on the family. The impact of a PICU admission extends beyond the patient and parents, potentially affecting healthy siblings who are navigating their own developmental challenges. Healthy siblings may face emotional distress, increased responsibilities, and disruptions in their daily routines, all of which can contribute to long-term negative outcomes if unaddressed. Thus, this study consists of two cohorts to understand the long-term physical, cognitive, and psychological outcomes in PICU survivors and their families, and the short-term impacts on siblings of critically ill children.",[110],"Post Intensive Care Syndrome (PICS)",[112,113,114],"PICS-p","Prospective Observational Cohort Study","Post Intensive Care Syndrome in Paediatrics (PICS-p)","2026-04-29",{"date":117,"type":118},"2026-05-05","ACTUAL",{"date":120,"type":118},"2025-02-11",{"date":122,"type":106},"2027-12",{"name":5,"class":6},2]