[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635534":3},{"organization":4,"armGroups":7,"interventions":28,"overallOfficials":42,"centralContacts":46,"locations":52,"responsibleParty":70,"collaborators":73,"id":81,"slug":82,"hasResults":83,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":89,"sex":90,"minAge":91,"maxAge":92,"enrollmentInfo":93,"targetDuration":33,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":106,"overallStatus":55,"whyStopped":33,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":126},{"fullName":5,"class":6},"University of Bologna","OTHER",[8,15,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Control (A) to Insect Bread (B) Sequence","EXPERIMENTAL","Participants follow a Mediterranean diet including control products (legume bread and\u002For standard fish burger) during the first intervention period, followed by a Mediterranean diet including insect protein-enriched bread (Acheta domesticus) during the second period. Each period lasts approximately 2 months. Participants are assigned to one of four randomized sequences according to a Latin square crossover design.",[13,14],"Other: Mediterranean Diet with Control Products (chronic phase)","Other: Mediterranean Diet with Insect Protein Bread (chronic phase)",{"label":16,"type":10,"description":17,"interventionNames":18},"Insect Bread (B) to Control (A) Sequence","Participants follow a Mediterranean diet including insect protein-enriched bread (Acheta domesticus) during the first intervention period, followed by a Mediterranean diet including control products (legume bread and\u002For standard fish burger) during the second period. Each period lasts approximately 2 months. Participants are assigned to one of four randomized sequences according to a Latin square crossover design.",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"Control (A) to Seaweed Burger (C) Sequence","Participants follow a Mediterranean diet including control products (legume bread and\u002For standard fish burger) during the first intervention period, followed by a Mediterranean diet including a seaweed-based burger during the second period. Each period lasts approximately 2 months. Participants are assigned to one of four randomized sequences according to a Latin square crossover design.",[13,23],"Other: Mediterranean Diet with Seaweed-Based Burger (chronic phase)",{"label":25,"type":10,"description":26,"interventionNames":27},"Seaweed Burger (C) to Control (A) Sequence","Participants follow a Mediterranean diet including a seaweed-based burger during the first intervention period, followed by a Mediterranean diet including control products (legume bread and\u002For standard fish burger) during the second period. Each period lasts approximately 2 months. Participants are assigned to one of four randomized sequences according to a Latin square crossover design.",[13,23],[29,34,38],{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"Mediterranean Diet with Control Products (chronic phase)","Mediterranean diet including control foods such as legume-based bread and standard fish burger, consumed five times per week for a period of 2 months.",[9,20,16,25],null,{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":33},"Mediterranean Diet with Insect Protein Bread (chronic phase)","Mediterranean diet including bread enriched with edible insect protein (Acheta domesticus), consumed five times per week over a 2-month intervention period.",[9,16],{"type":6,"name":39,"description":40,"armGroupLabels":41,"otherNames":33},"Mediterranean Diet with Seaweed-Based Burger (chronic phase)","Mediterranean diet including a burger made from edible seaweed, consumed five times per week over a 2-month intervention period.",[20,25],[43],{"name":44,"affiliation":5,"role":45},"Maria Letizia Petroni, Professor","PRINCIPAL_INVESTIGATOR",[47],{"name":44,"role":48,"phone":49,"phoneExt":50,"email":51},"CONTACT","051\u002F2143688","+39","marialetizia.petroni@unibo.it",[53],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"University of Bologna, Department of Medical and Surgical Sciences","RECRUITING","Bologna","BO","40138","Italy","IT",{"type":62,"coordinates":63},"Point",[64,65],11.33875,44.49381,{"lat":65,"lon":64},[68,69],{"name":44,"role":48,"phone":49,"phoneExt":50,"email":51},{"name":44,"role":45,"phone":33,"phoneExt":33,"email":33},{"type":45,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"Maria Letizia Petroni","Professor",[74,76,78],{"name":75,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna",{"name":77,"class":6},"University of Turin, Italy",{"name":79,"class":80},"Azienda Usl di Bologna","OTHER_GOV","100635534","sustainable-and-inclusive-use-of-alternative-proteins-in-mediterranean-supply-chains-cipromed-100635534",false,"NCT07553936","Sustainable and Inclusive Use of Alternative Proteins in Mediterranean Supply Chains (CIPROMED)","Circular and Inclusive Use of Alternative Proteins in Mediterranean Supply Chains (CIPROMED)","CIPROMED","Inclusion Criteria:\n\n* Providing signed informed consent,\n* Being between 18 and 65 years of age,\n* Having a body mass index (BMI) within the normal range, defined as between 18.5 and 24.9 kg\u002Fm² or Having a body mass index (BMI) between 25.0 and 34.9 kg\u002Fm², inclusive, corresponding to the overweight category or, at most, class I obesity.\n\nExclusion Criteria:\n\n* Positive and documented history of allergy to legumes, insects, microalgae, shellfish, mollusks, crustaceans, snails, insect venom, house dust mites, or any component (ingredient or additive) present in the food prototypes tested, or a confirmed or suspected diagnosis of Celiac Disease.\n* History of severe allergic reactions to any type of allergen.\n* Pregnancy or Breastfeeding",true,"ALL","18 Years","65 Years",{"count":94,"type":95},40,"ESTIMATED","INTERVENTIONAL",[98],"NA","This study investigates the effects of foods enriched with alternative protein sources, including edible insects, microalgae, hemp, and legumes, on appetite regulation, satiety, food preferences, and metabolic health in healthy adults and individuals with overweight. The study is part of the CIPROMED project, which aims to support sustainable and circular food systems in the Mediterranean area.\n\nThe study consists of two phases. In the acute phase, participants will consume different protein-enriched bread products in a controlled setting following a randomized crossover design. Each participant will be exposed to multiple test conditions, allowing within-subject comparisons of postprandial responses. Outcomes assessed during this phase include satiety, hunger, food preference, craving, and short-term energy intake, measured using validated scales and dietary assessment tools.\n\nIn the chronic phase, participants will follow structured dietary interventions over a longer period within a Mediterranean dietary framework. Participants will be assigned to different dietary patterns including alternative protein-based foods and control products. This phase aims to evaluate the effects of repeated consumption of alternative protein sources on metabolic parameters, gastrointestinal tolerance, nutritional status, and behavioral responses.\n\nThe study aims to assess the acceptability and physiological effects of alternative protein sources and to compare their impact with that of traditional protein sources commonly used in Mediterranean diets.",[101,102,103,104,105],"Food Preferences","Satiety and Food Intake","Appetite Regulation","Overweight (BMI > 25)","Gut Microbiota",[107,108,109,110,103,111,112,113,114,115,116,105],"Alternative Proteins","Edible Insects","Hemp Protein","Legume Protein","Overweight","Novel Foods","Microalgae (Protein)","Food Acceptability","Satiety","Metabolic Health","2026-04-28",{"date":119,"type":120},"2026-05-04","ACTUAL",{"date":122,"type":120},"2026-03-18",{"date":124,"type":95},"2027-01-31",{"name":5,"class":6},1]