[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601188":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":38,"centralContacts":43,"locations":48,"responsibleParty":121,"collaborators":33,"id":124,"slug":125,"hasResults":126,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":33,"eligibilityCriteria":130,"healthyVolunteers":126,"sex":131,"minAge":132,"maxAge":33,"enrollmentInfo":133,"targetDuration":33,"studyType":136,"phases":137,"briefSummary":139,"conditions":140,"keywords":142,"overallStatus":51,"whyStopped":33,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":156},{"fullName":5,"class":6},"Capital Medical University","OTHER",[8,15,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"True positive group","EXPERIMENTAL","Upper airway non-patency is defined as positive; otherwise, it is negative. The true positive group is defined as those for whom both the results of the speaking valve (SV) with the transtracheal end-expiratory pressure (TTPEE) measurement protocol and the bronchoscopy are positive.",[13,14],"Diagnostic Test: Speaking valve combined with airway pressure","Diagnostic Test: Bronchoscopy",{"label":16,"type":10,"description":17,"interventionNames":18},"False positive group","Upper airway non-patency is defined as positive; otherwise, it is negative. The false positive group is defined as the group in which the result of the speaking valve (SV) with the transtracheal end-expiratory pressure (TTPEE) measurement protocol is positive, and the result of the bronchoscopy is negative.",[13,14],{"label":20,"type":10,"description":21,"interventionNames":22},"True negative group","Upper airway non-patency is defined as positive; otherwise, it is negative. The true negative group is defined as those for whom both the results of the speaking valve (SV) with the transtracheal end-expiratory pressure (TTPEE) measurement protocol and the bronchoscopy are negative.",[13,14],{"label":24,"type":10,"description":25,"interventionNames":26},"False negative group","Upper airway non-patency is defined as positive; otherwise, it is negative. The false negative group is defined as the group in which the result of the speaking valve (SV) with the transtracheal end-expiratory pressure (TTPEE) measurement protocol is negative, and the result of the bronchoscopy is positive.",[13,14],[28,34],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"DIAGNOSTIC_TEST","Speaking valve combined with airway pressure","All patients wore speaking valves for 30 minutes, during which the transtracheal end-expiratory pressure was measured to assess the patency of the upper airway.",[24,16,20,9],null,{"type":29,"name":35,"description":36,"armGroupLabels":37,"otherNames":33},"Bronchoscopy","The same examiner performed bronchoscopy on all patients to assess upper airway patency.",[24,16,20,9],[39],{"name":40,"affiliation":41,"role":42},"Hongying Jiang, MD","Beijing Rehabilitation Hospital of Capital Medical University","STUDY_CHAIR",[44],{"name":40,"role":45,"phone":46,"phoneExt":33,"email":47},"CONTACT","+8656981555","6jhy@163.com",[49,61,77,91,106],{"facility":50,"status":51,"city":52,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":33,"geoPoint":33,"contacts":56},"Hunan Rehabilitation Hospital","RECRUITING","Hunan","410000","China","CN",[57],{"name":58,"role":45,"phone":59,"phoneExt":33,"email":60},"Pan Li","86-18674765825","584703769@qq.com",{"facility":62,"status":51,"city":63,"state":64,"zip":65,"country":54,"countryCode":55,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"Jiangbin Hospital of Guangxi Zhuang Autonomous Region","Guangxi","Jiangbin","530012",{"type":67,"coordinates":68},"Point",[69,70],120.24205,32.09142,{"lat":70,"lon":69},[73],{"name":74,"role":45,"phone":75,"phoneExt":33,"email":76},"Li Zheng","86-17776263283","819237886@qq.com",{"facility":41,"status":51,"city":78,"state":79,"zip":80,"country":54,"countryCode":55,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Beijing","Shijingshan","100144",{"type":67,"coordinates":82},[83,84],116.39723,39.9075,{"lat":84,"lon":83},[87],{"name":88,"role":45,"phone":89,"phoneExt":33,"email":90},"jingyi Ge","+861056981067","ge_jingyi2020@163.com",{"facility":92,"status":51,"city":93,"state":94,"zip":95,"country":54,"countryCode":55,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"YanBian University Hospital","Jilin City","Yanbian","133000",{"type":67,"coordinates":97},[98,99],126.5608,43.84652,{"lat":99,"lon":98},[102],{"name":103,"role":45,"phone":104,"phoneExt":33,"email":105},"Shenglan Jin","+864332660078","Shenglan91@163.com",{"facility":107,"status":51,"city":108,"state":109,"zip":110,"country":54,"countryCode":55,"cosmosGeoPoint":111,"geoPoint":115,"contacts":116},"Zhengzhou Central Hospital Affiliated to Zhengzhou University","Henan","Zhengzhou","450007",{"type":67,"coordinates":112},[113,114],112.22494,37.92189,{"lat":114,"lon":113},[117],{"name":118,"role":45,"phone":119,"phoneExt":33,"email":120},"Yajing Wang","86-15515645380","wangya568@163.com",{"type":122,"investigatorFullName":40,"investigatorTitle":123,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"PRINCIPAL_INVESTIGATOR","Sponsor-Investigator","100601188","sv-with-ttpee-measurement-predicts-upper-airway-patency-in-prolonged-tracheostomy-patients-100601188",false,"NCT07107243","SV With TTPEE Measurement Predicts Upper Airway Patency in Prolonged Tracheostomy Patients","Speaking Valves With Transtracheal End-expiratory Pressure Measurement Predicts Upper Airway Patency in Prolonged Tracheostomy Patients: A Multicenter, Prospective Study","Inclusion Criteria:\n\n* Weaned from ventilator more than 48 hours\n* No any organ failure\n* No sepsis\n* Stable heart rate and blood pressure\n* Lung infection under control\n* PCO2\\\u003C60mmHg\n* Patient and family sign informed consent form\n\nExclusion Criteria:\n\n* Serious dysfunction of vital organs\n* Inability to tolerate cuff deflation\n* Laryngopharyngeal trauma\n* Known severe upper airway obstruction before referrer to our department\n* Endoscopy(bronchoscopy or laryngoscopy) has been performed and the condition of the upper airway has known","ALL","18 Years",{"count":134,"type":135},300,"ESTIMATED","INTERVENTIONAL",[138],"NA","The aim of this study is to evaluate the feasibility of predicting upper airway patency in patients with prolonged tracheostomy using a non-invasive method combining speaking valve (SV) and transtracheal end-expiratory pressure (TTPEE) through a multicenter study.",[141],"Tracheostomy",[143,144,145,146],"transtracheal end-expiratory pressure","speaking valve","upper airway","prolonged tracheostomized patients","2026-01-17",{"date":149,"type":150},"2026-01-21","ACTUAL",{"date":152,"type":150},"2025-10-01",{"date":154,"type":135},"2026-10-31",{"name":5,"class":6},5]