[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100637126":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":10,"responsibleParty":18,"collaborators":10,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":27,"acronym":28,"eligibilityCriteria":29,"healthyVolunteers":24,"sex":30,"minAge":31,"maxAge":10,"enrollmentInfo":32,"targetDuration":35,"studyType":36,"phases":10,"briefSummary":37,"conditions":38,"keywords":40,"overallStatus":50,"whyStopped":10,"lastUpdateSubmitDate":51,"lastUpdatePostDateStruct":52,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":59,"locationsCount":10},{"fullName":5,"class":6},"Uppsala University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"ICU admission",null,"Any patient admitted to ICU in Sweden",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Michael Marks-Hultström, MD PhD","CONTACT","0186110000","michael.hultstrom@mcb.uu.se",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Michael Hultström","Associate professor","100637126","swedish-intensive-care-biobank-100637126",false,"NCT07582601","SWedish Intensive Care Biobank","Hereditary Influence on Risk Factors for Severe Illness in a Swedish Intensive Care Biobank","SWIC-B","Inclusion Criteria:\n\n* Adults admitted to intensive care in Sweden\n\nExclusion Criteria:\n\n* Non adults\n* Not admitted to intensive care","ALL","18 Years",{"count":33,"type":34},25000,"ESTIMATED","1 Year","OBSERVATIONAL","The goal of this observational study is to understand the genetic and molecular risk factors for developing critical illness in adult intensive care unit (ICU) patients in Sweden. The main questions it aims to answer are:\n\nWhich genetic variants are associated with increased risk of critical illness from conditions such as infections, sepsis, and organ failure?\n\nCan circulating proteins and metabolites mediate the effect of genetic risk factors on the severity of illness?\n\nParticipants will:\n\nProvide blood samples at ICU admission and again 3-6 months after discharge Consent to genetic analysis and data linkage with national health registries\n\nHave their ICU treatment and outcomes followed using registry and clinical data\n\nThis study aims to build a national infrastructure for rapid sample collection and analysis that can also support research in future pandemics.",[39],"Any Condition Underlying Critical Illness",[41,42,43,44,45,46,47,48,49],"critical illness","shock","sepsis","heart failure","ards","acute kidney injury","infection","organ failure","intensive care","NOT_YET_RECRUITING","2026-05-11",{"date":53,"type":54},"2026-05-13","ACTUAL",{"date":56,"type":34},"2027-01-01",{"date":58,"type":34},"2035-12-30",{"name":5,"class":6}]