[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599453":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":22,"responsibleParty":39,"collaborators":7,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":7,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":48,"minAge":49,"maxAge":7,"enrollmentInfo":50,"targetDuration":53,"studyType":54,"phases":7,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":65,"whyStopped":7,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"Annina Vischer, PD Dr. med.","Medical Outpatient Department and Hypertension Clinic, ESH Hypertension Centre of Excellence, University Hospital Basel","PRINCIPAL_INVESTIGATOR",[14,18],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},"CONTACT","0041613286630","annina.vischer@usb.ch",{"name":19,"role":15,"phone":20,"phoneExt":7,"email":21},"Thilo Burkard, PD Dr. med.","0041613287738","thilo.burkard@usb.ch",[23],{"facility":24,"status":7,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Medical Outpatient Department of the University Hospital Basel","Basel","Canton of Basel-City","4031","Switzerland","CH",{"type":31,"coordinates":32},"Point",[33,34],7.57327,47.55839,{"lat":34,"lon":33},[37,38],{"name":10,"role":15,"phone":16,"phoneExt":7,"email":17},{"name":10,"role":12,"phone":7,"phoneExt":7,"email":7},{"type":40,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100599453","swiss-cardiovascular-kidney-liver-metabolic-cklm-registry-100599453",false,"NCT07084688","Swiss Cardiovascular-Kidney-Liver-Metabolic (CKLM) Registry","Inclusion Criteria:\n\n* At least 18 years of age\n* Individuals diagnosed with cardiovascular-kidney-metabolic (CKM) syndrome stages 0 to 3 according to the American Heart Association (AHA) or liver disease defined by any of the following:\n\n  * For stage 0: Individuals without overweight\u002Fobesity, metabolic risk factors (normoglycemia, normotension, normal lipid profile), Chronic kidney disease (CKD), or Cardiovascular disease (CVD)\n  * Individuals with overweight\u002Fobesity or dysfunctional adipose tissue, without other metabolic risk factors or CKD\n  * Individuals with metabolic risk factors (hypertriglyceridemia, arterial hypertension, metabolic syndrome, diabetes) or CKD\n  * Subclinical Atherosclerotic cardiovascular disease (ASCVD) or subclinical heart failure (HF) in individuals with excess\u002Fdysfunctional adiposity, other metabolic risk factors, or CKD in the clinical assessment\\[2\\]\n  * Independent of CKM syndrome stages, individual with signs of hepatic steatosis on imaging\n* Willingness to provide informed consent\n\nExclusion Criteria:\n\n* Individuals with CKM syndrome stage 4 according to the AHA\n\n  \\* Individuals with clinical cardiovascular disease including:\n  * History of coronary artery disease, myocardial infarction, coronary artery intervention\n  * History of atrial fibrillation\n  * History of stroke\n  * Symptomatic peripheral artery disease (\\>stage I)\n  * History of symptomatic HF\n  * History of HF hospitalisation\n* Inability to sign informed consent",true,"ALL","18 Years",{"count":51,"type":52},1500,"ESTIMATED","10 Years","OBSERVATIONAL","The aim of this clinical and exploratory Swiss Cardiovascular-Kidney-Liver-Metabolic (CKLM) Registry is to establish high quality prevalence and incidence database for Cardiovascular-Kidney-Metabolic (CKM) syndrome, its major contributors, and the extent of the respective organ damaged.",[57,58],"Cradiovascular-kidney-liver-metabolic (CKLM) Syndrome","Cardiovascular-kidney-metabolic Syndrome",[60,61,62,63,64],"Cardiovascular-kidney-liver-metabolic (CKLM) syndrome","Cardiovascular disease (CVD)","Chronic kidney disease (CKD)","Organ-specific diseases","Cardiovascular-kidney-metabolic (CKM) syndrome","NOT_YET_RECRUITING","2025-07-17",{"date":68,"type":69},"2025-07-24","ACTUAL",{"date":71,"type":52},"2025-07-14",{"date":73,"type":52},"2040-07",{"name":5,"class":6},1]