[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100498942":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":21,"centralContacts":21,"locations":27,"responsibleParty":49,"collaborators":21,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":21,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":21,"overallStatus":29,"whyStopped":21,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University of Calgary","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"All eligible participants","EXPERIMENTAL","All eligible participants are randomly assigned to one of two interventions- early Head-Up Tilt Table procedure or early Implantable Loop Recorder. The assignment is random and at a 1:1 ratio between the two strategies.\n\nInterventions:\n\nDiagnostic Test: Head Up Tilt Table (HUT) Device: Implantable Loop Recorder",[13,14],"Diagnostic Test: Diagnostic Test: Head Up Tilt Table (HUT)","Device: Device: Implantable Loop Recorder",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DIAGNOSTIC_TEST","Diagnostic Test: Head Up Tilt Table (HUT)","Participant randomized to open-label diagnostic strategy. Results and all follow-up care to be in the hands of treating cardiologist as this is a pragmatic study.\n\nthe early HUT \\[protocol: supine pre-tilt phase 5 min, un-medicated HUT to 70 degrees for 20 minutes; if response negative then 400 μg of sublingual nitroglycerin and continued 70 degree tilt for 20 minutes\\]",[9],null,{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":21},"DEVICE","Device: Implantable Loop Recorder","ILR is a small subcutaneously implanted device, lasting up to 3 years, that records heart rhythms, and which may be either auto-triggered or patientactivated.",[9],[28],{"facility":5,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Calgary","Alberta","T2N 4Z6","Canada","CA",{"type":36,"coordinates":37},"Point",[38,39],-114.08529,51.05011,{"lat":39,"lon":38},[42,47],{"name":43,"role":44,"phone":45,"phoneExt":21,"email":46},"Dr. Robert S Sheldon, MD, PhD","CONTACT","403-220-8191","sheldon@ucalgary.ca",{"name":48,"role":44,"phone":21,"phoneExt":21,"email":21},"Dr. Robert S Sheldon, MD PhD",{"type":50,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100498942","syncope-trial-to-understand-tilt-testing-or-ecg-recording-tenth-prevention-of-syncope-trial-100498942",false,"NCT05776810","Syncope Trial to Understand Tilt Testing or ECG Recording Tenth Prevention of Syncope Trial","Syncope Trial to Understand Tilt Testing or ECG Recording. Tenth Prevention of Syncope","(POST10)","Inclusion Criteria:\n\n* age \\>50 years old\n* ≥1 syncope26 in the prior 12 months\n* diagnosis unclear after history, physical exam, and electrocardiogram\n* no apparent risk of death due to the cause of syncope\n\nExclusion Criteria:\n\n* cannot provide informed consent or attend routine follow up\n* have known left ventricular ejection fraction \\\u003C 50%,or have\n* pacemaker, ICD, or ICM\n* Class I indication for permanent pacing or ICD implantation\n* hypertrophic cardiomyopathy\n* a history of myocardial infarction within 3 months prior to enrolment\n* a major chronic co-morbid medical condition that would preclude 12 months of follow-up\n* bifascicular block\n* epilepsy proven by electroencephalography\n* syncope of known cause","ALL","50 Years","110 Years",{"count":63,"type":64},144,"ESTIMATED","INTERVENTIONAL",[67],"NA","The Study To Understand Tilt Tests versus Extended Recordings (STUTTER, POST 10) will test the hypothesis that first performing a diagnostic HUT in older patients with syncope of unknown cause will provide earlier and more diagnoses than inserting an ICM.",[70],"Syncope","2024-12-16",{"date":73,"type":74},"2024-12-19","ACTUAL",{"date":76,"type":74},"2023-05-01",{"date":78,"type":64},"2026-12-31",{"name":5,"class":6},1]