[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644401":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":59,"collaborators":20,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":20,"enrollmentInfo":71,"targetDuration":20,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":90,"whyStopped":20,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Imperial College London","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Rapid molecular screening","EXPERIMENTAL","During the study period all eligible patients will undergo the intervention",[13],"Diagnostic Test: Rapid molecular diagnostic test for CPE identification",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Rapid molecular diagnostic test for CPE identification","Participants will undergo a rectal swab and undergo rapid molecular testing for CPE colonisation",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Jon Otter","Guy's and St Thomas NHS Trust","PRINCIPAL_INVESTIGATOR",[27],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Research Governance and Integrity","CONTACT","020 7594 9832","RGIT@imperial.ac.uk",[33,49],{"facility":34,"status":20,"city":35,"state":20,"zip":20,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Charing Cross Hospital","London","United Kingdom","UK",{"type":39,"coordinates":40},"Point",[41,42],-0.12574,51.50853,{"lat":42,"lon":41},[45],{"name":46,"role":29,"phone":47,"phoneExt":20,"email":48},"Medicine & Integrated Care research office","+442033111234","imperial.admin_trustresearchcontracts@nhs.net",{"facility":50,"status":20,"city":35,"state":20,"zip":20,"country":36,"countryCode":37,"cosmosGeoPoint":51,"geoPoint":53,"contacts":54},"St Thomas' hospital",{"type":39,"coordinates":52},[41,42],{"lat":42,"lon":41},[55],{"name":56,"role":29,"phone":57,"phoneExt":20,"email":58},"R&D Governance team","+442071887188","gstt.randd@nhs.net",{"type":60,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100644401","tackling-resistance-and-healthcare-economics-through-cpe-screening-100644401",false,"NCT07663110","Tackling Resistance And HealthCare Economics Through CPE Screening","Multi-centre Evaluation of Carbapenemase-producing Enterobacterales (CPE) Prevalence and Transmission Dynamics, Recommendations on Screening Strategies, and Health Economics Outcomes Research Impact to Inform Policy Change","TRACE-CPE","Inclusion Criteria:\n\n* All adult (18 years or older) medical patients admitted to the acute medical unit during the implementation period who undergo routine rectal CPE testing as per local Trust policy and test positive for CPE colonisation through either the rapid test or culture-based methods.\n\nExclusion Criteria:\n\n* Patient refusal for rectal screening or\n* Clinical contraindication to rectal swab collection","ALL","18 Years",{"count":72,"type":73},16000,"ESTIMATED","INTERVENTIONAL",[76],"NA","The goal of this clinical study is to learn if it is possible to reduce the spread of resistant bacteria called CPEs (Carbapenemase producing Enterobacterales) between patients admitted to hospital.\n\nCPEs can be carried in the gut of people without making them ill. Normally when patients come into hospital, they may undergo a swab test on their bottom to see if CPEs can be grown. This test can take up to 24 hours to produce a result.\n\nThe investigators want to use a faster test which takes 2 hours to produce a result, and whether this can make a difference to CPE spread between person to person.\n\nThe main questions it aims to answer are:\n\n1. Why do people carry, transmit or get infected with CPE?\n2. If a faster test was used to look for CPE, would this be better at reducing patient spread in hospital?\n3. Is a faster test also more cost effective?\n\nParticipants will:\n\n1. Be tested by both the usual and faster test when they come into hospital by a swab on their bottom\n2. Where they test positive for CPE they will be asked to answer some questions about their health",[79,80],"Carbapenem-Resistant Enterobacteriaceae","Colonisation",[82,83,84,85,86,87,88,89],"infection prevention and control","health economics","rapid molecular diagnostics","carbapenem-resistant Enterobacterales","CPEs","CROs","MDROs","hospital transmission","NOT_YET_RECRUITING","2026-06-16",{"date":93,"type":94},"2026-06-23","ACTUAL",{"date":96,"type":73},"2026-08-01",{"date":98,"type":73},"2028-03-31",{"name":5,"class":6},2]