[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100518325":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":39,"centralContacts":43,"locations":52,"responsibleParty":71,"collaborators":30,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":30,"eligibilityCriteria":80,"healthyVolunteers":76,"sex":81,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":30,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":55,"whyStopped":30,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8,16,20],{"label":9,"type":10,"description":11,"interventionNames":12},"\"tACS Sham, tACS 10Hz, tACS 20Hz\" experimental order","EXPERIMENTAL","1. tACS Sham is a temporary non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for up to 30 second, it is not designed to entrain neuronal activity into any external regulatory frequency patterns.\n2. tACS 10Hz is a 10Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp or 20 or 40 minutes to entrain neuronal activity into 10Hz frequency patterns.\n3. tACS 20Hz is a 20Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for 20 or 40 minutes to entrain neuronal activity into 20Hz frequency patterns.",[13,14,15],"Device: tACS Sham","Device: tACS 10Hz","Device: tACS 20Hz",{"label":17,"type":10,"description":18,"interventionNames":19},"\"HD-tACS 20Hz, HD-tACS 10Hz, HD-tACS Sham\" experimental order","1. tACS 20Hz is a 20Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for 20 or 40 minutes to entrain neuronal activity into 20Hz frequency patterns.\n2. tACS 10Hz is a 10Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp or 20 or 40 minutes to entrain neuronal activity into 10Hz frequency patterns.\n3. tACS Sham is a temporary non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for up to 30 second, it is not designed to entrain neuronal activity into any external regulatory frequency patterns.",[13,14,15],{"label":21,"type":10,"description":22,"interventionNames":23},"\"HD-tACS 10Hz, HD-tACS 20Hz, HD-tACS Sham\" experimental order","1. tACS 10Hz is a 10Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp or 20 or 40 minutes to entrain neuronal activity into 10Hz frequency patterns.\n2. tACS 20Hz is a 20Hz non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for 20 or 40 minutes to entrain neuronal activity into 20Hz frequency patterns.\n3. tACS Sham is a temporary non-invasive electrical stimulation that applies a weak oscillatory current to the brain through the scalp for up to 30 second, it is not designed to entrain neuronal activity into any external regulatory frequency patterns.",[13,14,15],[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DEVICE","tACS Sham","Sham tACS will applied to the brain through the scalp for 20 minutes.",[21,17,9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"tACS 10Hz","10Hz tACS will applied to the brain through the scalp for 20 minutes.",[21,17,9],{"type":26,"name":36,"description":37,"armGroupLabels":38,"otherNames":30},"tACS 20Hz","20Hz tACS will applied to the brain through the scalp for 20 minutes.",[21,17,9],[40],{"name":41,"affiliation":5,"role":42},"Sheng Li, MD, Ph.D","PRINCIPAL_INVESTIGATOR",[44,48],{"name":41,"role":45,"phone":46,"phoneExt":30,"email":47},"CONTACT","(713) 797-7125","sheng.li@uth.tmc.edu",{"name":49,"role":45,"phone":50,"phoneExt":30,"email":51},"Shengai Li, MS","713-797-7561","shengai.li@uth.tmc.edu",[53],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"The University of Texas Health Science Center","RECRUITING","Houston","Texas","77030","United States","US",{"type":62,"coordinates":63},"Point",[64,65],-95.36327,29.76328,{"lat":65,"lon":64},[68,70],{"name":69,"role":45,"phone":46,"phoneExt":30,"email":47},"Sheng Li, MD, PhD",{"name":49,"role":45,"phone":50,"phoneExt":30,"email":51},{"type":42,"investigatorFullName":72,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"Sheng Li","Professor","100518325","tacs-for-neuropathic-pain-management-after-sci-100518325",false,"NCT06029075","tACS for Neuropathic Pain Management After SCI","tACS Brain Neuromodulation for Sensory and Motor Recovery After Neurological Impairments","Inclusion\u002Fexclusion criteria for SCI subjects\n\nInclusion criteria: A patient who\n\n1. has neuropathic pain after traumatic spinal cord injury or amputation or brain injury;\n2. has chronic pain, \\>3 months;\n3. is between 18 to 75 years of age;\n4. is stable on oral pain medications at least two weeks. Patients are allowed to continue their pain medications, i.e., no change in pain medications.\n\nNOTE: we plan to begin the study with the spinal cord injury (SCI) subject population as a cohort first, then expand to other subject populations\n\nExclusion criteria: Patients will be excluded if they\n\n1. are currently adjusting oral pain medications for their neuropathic pain;\n2. have pain, but not neuropathic, e.g., from inflammation at the incision wound of the residual limb or neuroma;\n3. have a pacemaker metal implants or supplemental oxygen;\n4. have amputation in their arm(s);\n5. fail to have a motor contraction in the arm muscles with TMS;\n6. are not able to follow commands, or to give consent;\n7. have asthma or other pulmonary disease;\n8. are not medically stable;\n9. have preexisting psychiatric disorders;\n10. alcohol or drug abuse.","ALL","18 Years","75 Years",{"count":85,"type":86},14,"ESTIMATED","INTERVENTIONAL",[89],"NA","The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for neuropathic pain management in people after spinal cord injury.",[92],"Neuropathic Pain Management",[94,95],"tACS","Neuropathic Pain","2026-06-01",{"date":98,"type":99},"2026-06-03","ACTUAL",{"date":101,"type":99},"2025-09-01",{"date":103,"type":86},"2028-03-31",{"name":5,"class":6},1]