[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636614":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":38,"locations":26,"responsibleParty":44,"collaborators":48,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":26,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":26,"enrollmentInfo":60,"targetDuration":26,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":78,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":26},{"fullName":5,"class":6},"Hainan Medical College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Tai Chi Group","EXPERIMENTAL","Participants in this group receive instruction in Yang-style 24-form Tai Chi from a nationally certified master coach. Tai Chi classes are offered five days per week, and participants are required to attend at least three sessions per week. Each session lasts 60 minutes, including warm-up, Tai Chi practice, cool-down, and Q\\&A. The intervention duration is 12 weeks. Class size is limited to 10-15 participants to ensure individualized guidance.",[13],"Behavioral: Tai Chi Exercise",{"label":15,"type":16,"description":17,"interventionNames":18},"Health Education Control Group","ACTIVE_COMPARATOR","Participants in this group attend health education seminars led by professional medical and health management staff. Seminar topics include nutrition, chronic disease management, fall prevention, and safe medication use. The intervention duration is 12 weeks. After the intervention ends, this group is offered free Tai Chi classes to ensure ethical equipoise.",[19],"Behavioral: Health Education",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Tai Chi Exercise","Yang-style 24-form Tai Chi taught by a nationally certified master coach. Classes are offered five days per week, with participants required to attend at least three sessions per week, for a total of 12 weeks (target: ≥36 sessions). Each 60-minute session includes a 10-minute warm-up, 35 minutes of Tai Chi practice, 10 minutes of cool-down (including standing meditation and breathing exercises), and 5 minutes for questions and home practice reminders. Class size is limited to 10-15 participants.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Health Education","Structured health education program delivered by professional medical and health management staff. Seminars cover topics including nutrition and dietary guidance, chronic disease management (hypertension, diabetes), fall prevention strategies, safe medication use, and general health literacy for older adults. The intervention runs for 12 weeks. Participants receive the same health screening, evaluation, and feedback benefits as the Tai Chi group. Free Tai Chi classes are offered to this group after the intervention period ends.",[15],[32,35],{"name":33,"affiliation":5,"role":34},"Baichao Xu, PhD","STUDY_DIRECTOR",{"name":36,"affiliation":37,"role":34},"Ziheng Ning, PhD","Macao Polytechnic University",[39],{"name":40,"role":41,"phone":42,"phoneExt":26,"email":43},"Zhide Liang, MS","CONTACT","0853-65597656","p2516238@mpu.edu.mo",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Zhide Liang","Doctoral Student \u002F Study Coordinator",[49],{"name":37,"class":6},"100636614","tai-chi-intervention-for-balance-function-in-older-adults-predictive-and-modifying-roles-of-circadian-age-100636614",false,"NCT07567976","Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age","Effects of Tai Chi on Balance Function in Community-Dwelling Older Adults: A Randomized Controlled Trial Examining the Predictive and Modifying Roles of Circadian Age, With Multi-Omics and Brain Function Assessments","Inclusion Criteria:\n\n* Aged 55 years or older\n* Community-dwelling\n* Able to walk independently (assistive devices such as canes are permitted)\n* Berg Balance Scale (BBS) score ≤52 at screening\n* Able to understand and follow verbal instructions\n* Willing to wear a wrist accelerometer continuously for 7 days at baseline\n* Willing to accept random group assignment\n* Willing to undergo blood collection during the study\n* Provides written informed consent\n\nExclusion Criteria:\n\n* Regular Tai Chi or yoga practice (more than once per week) within the past 6 months\n* Severe cognitive impairment (Montreal Cognitive Assessment \\[MoCA\\] score \\\u003C20 at screening, or previously diagnosed dementia)\n* Unstable cardiovascular disease (myocardial infarction, stroke, or hospitalization within the past 3 months)\n* Severe musculoskeletal disease that limits exercise participation\n* Neurological diseases affecting balance (e.g., Parkinson's disease, severe peripheral neuropathy)\n* Currently participating in another exercise intervention study\n* Planned surgery or extended absence during the study period\n* Contraindications to functional near-infrared spectroscopy (fNIRS) examination (e.g., scalp injury, metallic implants in the head region)\n* Severe psychiatric illness (e.g., schizophrenia, bipolar disorder)\n* Considered unable to safely participate in moderate-intensity physical activity as judged by the study physician or attending healthcare provider",true,"ALL","55 Years",{"count":61,"type":62},90,"ESTIMATED","INTERVENTIONAL",[65],"NA","This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control group. The primary outcome is balance function measured by the Berg Balance Scale. Secondary outcomes include physical function, psychological well-being, cognitive function, and sleep quality. The study also explores the predictive and modifying roles of baseline circadian age on intervention outcomes.",[68,69,70],"Aging","Postural Balance","Accidental Falls",[72,73,74,75,76,77],"Tai Chi","Tai Ji Quan","Mind-Body Exercise","Older Adults","Fall Prevention","Circadian Rhythm","NOT_YET_RECRUITING","2026-06-30",{"date":81,"type":82},"2026-07-02","ACTUAL",{"date":84,"type":62},"2026-06-01",{"date":86,"type":62},"2027-03",{"name":46,"class":6}]