[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615203":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":22,"centralContacts":27,"locations":38,"responsibleParty":58,"collaborators":32,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":32,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":32,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":83,"overallStatus":41,"whyStopped":32,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"El-Sahel Teaching Hospital","OTHER_GOV",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with morbid obesity","OTHER","Tailored SADI-S",[13],"Procedure: Bariatric surgery",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Bariatric surgery","Only surgical procedure in the study",[9],[21],"SADI-S",[23],{"name":24,"affiliation":25,"role":26},"Ahmed M Yousry, Lecturer of Surgery","El Sahel Teaching Hospital, Cairo, Egypt","PRINCIPAL_INVESTIGATOR",[28,34],{"name":29,"role":30,"phone":31,"phoneExt":32,"email":33},"Ahmed MFMH Mansour, Lecturer of Surgery","CONTACT","00201227196753",null,"ahmed.farid@alexmed.edu.eg",{"name":35,"role":30,"phone":36,"phoneExt":32,"email":37},"Mostafa R ElKeleny, Assistant Professor of Surgery","00201005814622","mostafa.refaie@alexmed.edu.eg",[39],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"El Sahel Teaching Hospital","RECRUITING","Cairo","Greater Cairo","11697","Egypt","EG",{"type":48,"coordinates":49},"Point",[50,51],31.24967,30.06263,{"lat":51,"lon":50},[54,57],{"name":24,"role":30,"phone":55,"phoneExt":32,"email":56},"00201273307922","drahmedyousry1981@gmail.com",{"name":24,"role":26,"phone":32,"phoneExt":32,"email":32},{"type":26,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Ahmed mohamed Yousry","Dr","100615203","tailored-stapled-sadi-s-initial-report-and-preliminary-results-100615203",false,"NCT07289555","Tailored Stapled SADI-S: Initial Report and Preliminary Results","Tailored Stapled Single Anastomosis Duodeno-ileal Bypass With Sleeve Gastrectomy (SADI-S): Initial Report and Preliminary Results","Inclusion Criteria:\n\n* Adults aged 18-65 years.\n* BMI ≥35 kg\u002Fm² or BMI ≥30 kg\u002Fm² with obesity-related comorbidities such as type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, obstructive sleep apnea, or non-alcoholic fatty liver disease.\n* Willingness to adhere to follow-up visits and testing.\n* Indicated for revisional SADI-S post sleeve gastrectomy for inadequate weight loss or weight regain.\n\nExclusion Criteria:\n\n* Severe uncontrolled medical or psychiatric conditions preventing adherence to the protocol.\n* Known short bowel syndrome or previous extensive bowel resections or intraoperative finding of extensive bowel adhesions.","ALL","18 Years","65 Years",{"count":72,"type":73},40,"ESTIMATED","INTERVENTIONAL",[76],"NA","Obesity is a serious health problem worldwide and can lead to many diseases such as diabetes, high blood pressure, heart disease, and sleep apnea. When lifestyle changes and medications are not enough, metabolic and bariatric surgery (MBS) is currently the most effective and long-lasting treatment option.\n\nThis study focuses on one of the newer types of bariatric surgery called Single Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy (SADI-S). This procedure combines two parts:\n\nSleeve gastrectomy, which reduces the size of the stomach so the patient feels full after eating a small amount.\n\nDuodeno-ileal bypass, which shortens the path food takes through the small intestine to reduce calorie absorption.\n\nOur hospital's surgical team is studying a tailored version of this operation, where the length of the bypassed intestine is adjusted to each patient's anatomy. We believe this personalized approach may improve weight loss results while lowering the risk of vitamin and nutrient deficiencies.\n\nThe study will include 40 adult patients with obesity who are undergoing SADI-S surgery, either as their first weight loss operation or as a revision surgery after an earlier sleeve gastrectomy. During the operation, surgeons will measure the total length of each patient's small intestine and use a formula to decide how much of it should be bypassed. The duodeno-ileal connection will be made using a stapled technique, which is expected to be safe and efficient.\n\nAfter surgery, patients will be followed regularly at 1, 3, 6, 9, and 12 months, and then once per year. At each visit, the study team will monitor weight loss, body mass index (BMI), resolution of diabetes and other obesity-related conditions, nutritional status (including vitamins and minerals), and any side effects such as diarrhea, reflux, or nutritional problems.\n\nThe goal of this study is to learn whether this tailored SADI-S technique can provide strong, sustained weight loss and health improvement with fewer long-term complications. The results will help improve surgical planning for future patients by showing whether measuring and customizing the bypass length is safer and more effective than using a fixed length.\n\nAll data collected will be kept confidential. Patients' participation in the study will not change their regular care or follow-up, and they can withdraw at any time without affecting their treatment.",[79,80,81,82],"Morbid Obesity","Bariatric Surgery","Malnutrition","Comorbidities",[21,17,84,85,86],"Limb length tailoring","Weight loss outcomes","Nutritional status","2025-12-04",{"date":89,"type":90},"2025-12-17","ACTUAL",{"date":92,"type":90},"2024-06-01",{"date":94,"type":73},"2026-12-31",{"name":5,"class":6},1]