[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633935":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":33,"responsibleParty":46,"collaborators":18,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":18,"eligibilityCriteria":54,"healthyVolunteers":50,"sex":55,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":18,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":73,"whyStopped":18,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Essilor International","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"More myopic eye: MCL1; Less myopic eye: MCL2","EXPERIMENTAL","Each participant wears the study eyeglasses containing both Myopia Control Lens 1 (MCL1) and Myopia Control Lens 2 (MCL2) design, with one type of lens in each eye throughout the study period. MCL1 will be worn in the more myopic eye, and MCL2 in the less myopic eye for a period of 12 months.",[13],"Device: More myopic eye: MCL1; Less myopic eye: MCL2",[15],{"type":16,"name":9,"description":11,"armGroupLabels":17,"otherNames":18},"DEVICE",[9],null,[20],{"name":21,"affiliation":22,"role":23},"Theophila Ang","Essilor R&D Centre Singapore","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":18,"email":29},"Celine Carimalo","CONTACT","+65 6589 9216","carimalc@essilor.com.sg",{"name":31,"role":27,"phone":18,"phoneExt":18,"email":32},"Thomas Boudenne","thomas.boudenne@essilor.com",[34],{"facility":22,"status":18,"city":35,"state":18,"zip":18,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Singapore","SG",{"type":38,"coordinates":39},"Point",[40,41],103.85007,1.28967,{"lat":41,"lon":40},[44],{"name":26,"role":27,"phone":45,"phoneExt":18,"email":29},"+65 65899216",{"type":47,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100633935","targeted-lens-intervention-for-myopic-anisometropia-in-children-100633935",false,"NCT07533149","Targeted Lens Intervention for Myopic Anisometropia in Children","Clinical Investigation of Targeted Lens Intervention in the Management of Myopic Anisometropia in Children","Inclusion Criteria:\n\n1. Voluntary\n2. Informed consent of parent\u002Fguardian and assent of participant\n3. Age equal to or greater than 6 years old and less than 13 years at the time of signing informed consent and assent\n4. SER equal or less than -0.50 D and equal or greater than .5.00 D with astigmatism not more than 2.50 D\n5. Difference in SER (anisometropia) between two eyes .1.00 D\n6. Best corrected visual acuity (BCVA) better than or equal to +0.20 LogMAR in each eye\n7. Agree to wear study spectacles for .12 hours\u002Fday and 7 days\u002Fweek\n8. Willingness and ability to participate in investigation for 12 months and attend scheduled visits punctually\n9. Agree for no concurrent involvement in other myopia control treatment\n\nExclusion Criteria:\n\n1. History or presence of an ocular disease affecting refractive status\n2. History or presence of strabismus\n3. Presence of amblyopia\n4. Current or previous use of atropine and\u002For orthokeratology\n5. Known allergy to cycloplegic agents\n6. Contraindication to cycloplegic agents\n7. Cognitive or psychological vulnerability","ALL","6 Years","13 Years",{"count":59,"type":60},20,"ESTIMATED","INTERVENTIONAL",[63],"NA","The goal of this clinical trial is to learn if our research spectacles will lower the difference in prescription (spectacles degree) between the eyes in children between 6 to 13 years old with anisometropic myopia. Anisometropic myopia is when the difference in myopia prescription between the two eyes are more than 1 diopter. The main question it aims to answer is:\n\n* How the eye responds to the research spectacles over time by measuring:\n\n  1. Change in axial length: the physical length of the eye from front to back.\n  2. Change in cycloplegic spherical equivalent refraction: an accurate measurement of the eye's prescription taken while the focusing muscles are temporarily relaxed with eye drops.\n\n     Participants will:\n* Wear the study spectacles\n* Visit Essilor R\\&D Centre and an eye clinic for follow-up sessions",[66,67],"Anisometropia","Myopia",[69,70,71,72],"myopia control","anisometropia","axial length","spherical equivalent refraction","NOT_YET_RECRUITING","2026-04-09",{"date":76,"type":77},"2026-04-16","ACTUAL",{"date":79,"type":60},"2026-04",{"date":81,"type":60},"2027-07",{"name":5,"class":6},1]