[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100473051":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":19,"locations":29,"responsibleParty":49,"collaborators":10,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":10,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":10,"enrollmentInfo":62,"targetDuration":65,"studyType":66,"phases":10,"briefSummary":67,"conditions":68,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Nanjing First Hospital, Nanjing Medical University","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"TAVR in aortic valve disease",null,[12],"Device: transcatheter heart valve",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","transcatheter heart valve","patients with severe aortic valve disease underwent transcatheter heart valve",[9],[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Jun-Jie Zhang, MD","CONTACT","+86-25-52271350","jameszll@163.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Jing Kan, MPH","+86-25-52271398","kanjingok@126.com",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Nanjing First Hospital","RECRUITING","Nanjing","Jiangsu","210006","China","CN",{"type":39,"coordinates":40},"Point",[41,42],118.77778,32.06167,{"lat":42,"lon":41},[45],{"name":46,"role":22,"phone":47,"phoneExt":10,"email":48},"Shao-Liang Chen","+86 13605157029","chmengx@126.com",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Junjie Zhang","Vice chief","100473051","tavr-for-aortic-valve-disease-100473051",false,"NCT05439863","TAVR for Aortic Valve Disease","Transcatheter Aortic Valve Replacement for Severe Aortic Valve Disease: Multi-center, Real-word Registry","Inclusion Criteria:\n\n1. Clinical diagnosis of severe aortic stenosis or aortic regurgitation\n2. Patients undergo transcatheter aortic valve replacement\n\nExclusion Criteria:\n\npatients refuse the clinical follow-up","ALL","18 Years",{"count":63,"type":64},5000,"ESTIMATED","15 Years","OBSERVATIONAL","Transcatheter aortic valve replacement (TAVR) has became an important treatment of severe aortic stenosis (AS). Several randomized clinical trials showed that TAVR was non-inferior or superior to surgical aortic valve replacement (SAVR). However, many different issues have emerged: TAVR in younger patients? valve leaflet thrombosis? transcatheter valve durability? coronary reaccess after TAVR? TAVR in bicuspid aortic valve? TAVR in aortic regurgitation? etc. Hence, a prospective, multicenter database is created to provide the real-word data for these questions.",[69],"Aortic Valve Disease","2024-11-13",{"date":72,"type":73},"2024-11-15","ACTUAL",{"date":75,"type":73},"2022-07-01",{"date":77,"type":64},"2037-12-30",{"name":5,"class":6},1]