[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100555825":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":40,"centralContacts":44,"locations":49,"responsibleParty":63,"collaborators":66,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":31,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":31,"enrollmentInfo":83,"targetDuration":31,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":31,"overallStatus":52,"whyStopped":31,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Education University of Hong Kong","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Personalised tDCS group","EXPERIMENTAL","Participants who are assigned to the personalised group will receive anodal tDCS over a individualized stimulation site.",[13],"Device: Personalized Experimental Transcranial Direct Current Stimulation (tDCS)",{"label":15,"type":10,"description":16,"interventionNames":17},"Conventional tDCS group","Participants who are assigned to the Conventional group will receive anodal tDCS over F3.",[18],"Device: Conventional Experimental Transcranial Direct Current Stimulation (tDCS)",{"label":20,"type":21,"description":22,"interventionNames":23},"Sham control group","SHAM_COMPARATOR","Participants who are assigned to the Conventional group will receive sham tDCS. The active stimulation will be delivered for the first 30 seconds only.",[24],"Device: Sham Transcranial Direct Current Stimulation (tDCS)",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DEVICE","Personalized Experimental Transcranial Direct Current Stimulation (tDCS)","This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants will receive 20 minutes of active stimulation with a 2mA intensity over personalized brain regions based on the particular neural correlates of socio-affective processing.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Sham Transcranial Direct Current Stimulation (tDCS)","This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants assigned to the sham control group will only receive 30 seconds of active stimulation.",[20],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Conventional Experimental Transcranial Direct Current Stimulation (tDCS)","This study will deliver tDCS sessions for a maximum of ten sessions in two weeks' time. Participants will receive 20 minutes of active stimulation with a 2mA intensity with anode placed over F3.",[15],[41],{"name":42,"affiliation":5,"role":43},"Nichol ML Wong, PhD","PRINCIPAL_INVESTIGATOR",[45],{"name":42,"role":46,"phone":47,"phoneExt":31,"email":48},"CONTACT","852-29487431","nmlwong@eduhk.hk",[50],{"facility":51,"status":52,"city":53,"state":31,"zip":31,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"The Education University of Hong Kong","RECRUITING","Hong Kong","HK",{"type":56,"coordinates":57},"Point",[58,59],114.17469,22.27832,{"lat":59,"lon":58},[62],{"name":42,"role":46,"phone":47,"phoneExt":31,"email":48},{"type":43,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"WONG Man Lok Nichol","Assistant Professor",[67,69,71],{"name":68,"class":6},"The University of Hong Kong",{"name":70,"class":6},"Chinese University of Hong Kong",{"name":72,"class":6},"Hong Kong Baptist University","100555825","tdcs-in-people-with-subthreshold-depression-100555825",false,"NCT06517121","tDCS in People With Subthreshold Depression","Personalised Transcranial Direct Current Stimulation to Reduce Daily Loneliness in People With Subthreshold Depression","Inclusion Criteria:\n\n* No histories of learning impairment, major psychiatric disorders including Major Depressive Disorder or neurological disorders\n* At least primary school education\n* Subthreshold depression\n\nExclusion Criteria:\n\n* On medication or treatments within 2 weeks prior to the beginning of the study that would affect the individual's brain, cognitive and affective functions",true,"ALL","18 Years",{"count":84,"type":85},204,"ESTIMATED","INTERVENTIONAL",[88],"NA","This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression.",[91],"Subthreshold Depression","2026-01-29",{"date":94,"type":95},"2026-02-02","ACTUAL",{"date":97,"type":95},"2026-01-16",{"date":99,"type":85},"2027-01",{"name":5,"class":6},1]