[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545483":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":41,"responsibleParty":57,"collaborators":26,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":26,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":26,"enrollmentInfo":70,"targetDuration":26,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":26,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Seoul National University Bundang Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Esomeprazole-containing sequential H. pylori eradication therapy (conventional method)","ACTIVE_COMPARATOR","esomeprazole (40 mg) plus amoxicillin (1000 mg) twice a day for initial 5 days, and then esomeprazole (40 mg) with clarithromycin (500 mg) and metronidazole (500 mg) twice a day for the remaining 5 days.",[13],"Drug: Esomeprazole-containing sequential H. pylori eradication therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Tegoprazan-containing sequential H. pylori eradication therapy (experimental method)","EXPERIMENTAL","tegoprazan (50 mg) plus amoxicillin (1000 mg) twice a day for initial 5 days, and then tegoprazan (50 mg) with clarithromycin (500 mg) and metronidazole (500 mg) twice a day for the remaining 5 days.",[19],"Drug: Tegoprazan-containing sequential H. pylori eradication therapy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Tegoprazan-containing sequential H. pylori eradication therapy","tegoprazan was administered, instead propton-pump inhibitor, as acid blockade in H. pylori eradication sequential therapy",[15],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Esomeprazole-containing sequential H. pylori eradication therapy","Esomeprazole was administered as acid blockade in H. pylori eradication sequential therapy (conventional acid blockade method for sequential eradication therapy)",[9],[32],{"name":33,"affiliation":5,"role":34},"Nayoung Kim, Prof.","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Jungwon Lee, Dr.","CONTACT","821093567758","saludos@naver.com",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":26,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Seongnam-si","Gyeonggi-do","463-707","South Korea",{"type":49,"coordinates":50},"Point",[51,52],127.13778,37.43861,{"lat":52,"lon":51},[55],{"name":56,"role":34,"phone":26,"phoneExt":26,"email":26},"Nayoung Kim, M.D.,Ph.D.",{"type":34,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Nayoung Kim","Professor","100545483","tegoprazan-containing-sequential-for-h-pylori-100545483",false,"NCT06382493","Tegoprazan-containing Sequential for H. Pylori","Efficacy of Tegoprazan-containing Sequential Therapy Compared to Proton Pump Inhibitor-based Eradication in South Korea, a Region With High Antimicrobial Resistance: A Prospective Randomized Single Tertiary Center Study","Inclusion Criteria:\n\nPatients who had H. pylori infection proved by positive test result of urea breath test (UBT), rapid urase test or pathologic examination (warthin-giemsa staining)\n\nExclusion Criteria:\n\n* congestive heart failure, NYHA III or IV\n* end-stage renal disease\n* alcoholics\n* drug abusers\n* pregnant or nursing women",true,"ALL","18 Years",{"count":71,"type":72},400,"ESTIMATED","INTERVENTIONAL",[75],"NA","As H. pylori eradication, the investigators prepared a randomized controlled clinical trial whether tegoprazan-containing 10-day sequential treatment was effective compared to conventional PPI-containing 10-day sequential eradication therapy",[78],"Helicobacter Pylori Infection","2026-04-23",{"date":81,"type":82},"2026-04-28","ACTUAL",{"date":84,"type":82},"2021-02-01",{"date":86,"type":72},"2026-12-12",{"name":5,"class":6},1]