[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630809":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":25,"responsibleParty":30,"collaborators":25,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":25,"eligibilityCriteria":40,"healthyVolunteers":36,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":25,"studyType":47,"phases":48,"briefSummary":50,"conditions":51,"keywords":54,"overallStatus":59,"whyStopped":25,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":25},{"fullName":5,"class":6},"Jiangsu Taizhou People's Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Digital-Smart Integrated Prevention Group","EXPERIMENTAL","Participants in this arm receive a village doctor-led, digital-smart integrated management program. This intervention comprises three key components:\n\n1. A digital chronic disease management system utilizing an IoT gateway and wearable devices (HUAWEI Band 6) for continuous health monitoring.\n2. A structured multidimensional lifestyle intervention that includes monthly peer-support cardiac rehabilitation sessions and tailored behavioral education on diet, smoking, and sleep.\n3. Integrated care services that provide guideline-directed medical therapy (GDMT) and access to remote tele-consultations with cardiovascular specialists.",[13],"Other: Telemedicine-Based Integrated Care Model",{"label":15,"type":16,"description":17,"interventionNames":18},"Conventional Management","ACTIVE_COMPARATOR","Participants in this control group receive standard diagnosis and treatment for common chronic diseases (such as hypertension, diabetes, and COPD) provided by primary care physicians. They also receive standard Basic Public Health Services (BPHS), which primarily include quarterly follow-up visits, an annual free physical examination for residents over 65, and the distribution of health education materials.",[19],"Other: Conventional Management Group",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Telemedicine-Based Integrated Care Model","This intervention is a village doctor-led, telemedicine-supported integrated care model. It utilizes an Internet of Things (IoT)-enabled digital health platform that automatically collects data from clinic devices and patient wearables (HUAWEI Band 6). The platform provides primary care doctors with clinical decision support for Guideline-Directed Medical Therapy (GDMT) and the atrial fibrillation ABC pathway, facilitating remote tele-consultations with cardiovascular specialists when clinical targets are not met. Furthermore, it includes a structured lifestyle intervention featuring monthly peer-support cardiac rehabilitation sessions at township health centers, along with automated, personalized behavioral education based on quarterly assessments",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Conventional Management Group","Participants in the conventional management group receive standard medical care and routine Basic Public Health Services (BPHS) provided by primary care physicians at their local village clinics. This includes standard quarterly follow-up visits for common chronic disease management, an annual free physical examination, and the distribution of general health education materials. Unlike the intervention arm, these participants do not use the IoT-enabled digital health platform, wearable monitoring devices, or participate in the structured multidimensional lifestyle intervention program.",[15],{"type":31,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Ming Chu","Chief Physician","100630809","telemedicine-based-integrated-care-for-heart-failure-prevention-in-older-patients-with-atrial-fibrillation-miracle-af-iii-100630809",false,"NCT07492498","Telemedicine-Based Integrated Care for Heart Failure Prevention in Older Patients With Atrial Fibrillation (MIRACLE-AF III)","Prevention of Incident Heart Failure With a Telemedicine-based Integrated Care Model Among Older Atrial Fibrillation Patients in Rural China: the MIRACLE-AF-Prevention Cluster Randomized Trial","Inclusion Criteria:\n\n1. Permanent residents with household registration in primary care jurisdictions of Jiangsu Province, aged 65 to 80 years;\n2. Availability of an electrocardiogram confirming atrial fibrillation, or an official diagnosis certificate of atrial fibrillation issued by a specialist;\n3. Receiving healthcare management from the primary medical institution nearest to the place of residence;\n4. Capable of understanding and signing the informed consent form.\n\nExclusion Criteria:\n\n1. A definite history of heart failure, or a confirmed diagnosis of cardiac dysfunction via echocardiography and\u002For NT-proBNP screening. Diagnostic criteria: Presence of typical heart failure symptoms\u002Fsigns, accompanied by either reduced left ventricular ejection fraction (HFrEF, LVEF \\\u003C 40%), mildly reduced left ventricular ejection fraction (HFmrEF, LVEF 40-49%), or preserved left ventricular ejection fraction with elevated NT-proBNP and structural heart disease changes (HFpEF, LVEF ≥ 50%);\n2. Expected survival of less than 3 months;\n3. Patients with severe renal insufficiency (Ccr \\\u003C 30 mL\u002Fmin) or those undergoing dialysis treatment;\n4. Cardiac dysfunction caused by various reversible secondary causes, including hyperthyroid heart disease, anemic heart disease, and uncorrected congenital heart disease;\n5. Presence of indications for pacemaker implantation without subsequent device placement;\n6. Patients with chronic obstructive pulmonary disease (COPD) complicated by type III respiratory failure;\n7. Special populations such as patients with mental illness.","ALL","65 Years","80 Years",{"count":45,"type":46},1268,"ESTIMATED","INTERVENTIONAL",[49],"NA","The purpose of this study is to prevent heart failure in older adults (aged 65-80 years) living in rural China who have atrial fibrillation but do not currently have heart failure. Because atrial fibrillation significantly increases the risk of developing heart failure , this cluster-randomized trial tests whether a telemedicine-supported, village doctor-led integrated care model can improve long-term cardiovascular health compared to standard care. Participants are assigned by their local village clinic to receive either conventional routine medical care or a digital-smart management program. The integrated program includes using wearable devices to monitor daily health, participating in structured lifestyle improvement programs focusing on exercise, diet, smoking cessation, and sleep, and receiving optimized medication plans supported by remote cardiovascular specialists. Researchers will measure overall improvements in cardiovascular health using the Life's Essential 8 score at 12 months, track major cardiovascular events like heart failure hospitalizations or stroke at 36 months, and evaluate the development of asymptomatic heart dysfunction at 48 months.",[52,53],"Atrial Fibrillation","Heart Failure",[55,56,57,58],"Telemedicine Integrated Care","Integrated Care","Primary Prevention","Cardiovascular Diseases","NOT_YET_RECRUITING","2026-03-19",{"date":62,"type":63},"2026-03-25","ACTUAL",{"date":65,"type":46},"2026-04-01",{"date":67,"type":46},"2030-04-01",{"name":5,"class":6}]