[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601199":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":8,"centralContacts":13,"locations":21,"responsibleParty":43,"collaborators":45,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":7,"enrollmentInfo":60,"targetDuration":7,"studyType":63,"phases":7,"briefSummary":64,"conditions":65,"keywords":7,"overallStatus":24,"whyStopped":7,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Buck Institute for Research on Aging","OTHER",null,[9],{"name":10,"affiliation":11,"role":12},"James Yurkovich, PhD","Phenome Health, The Buck Institute for Research on Aging","PRINCIPAL_INVESTIGATOR",[14,19],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Brianna Stubbs, Research Assistant Professor, PhD.","CONTACT","(415) 209-2072","TIME-Study@buckinstitute.org",{"name":20,"role":16,"phone":7,"phoneExt":7,"email":18},"Alison Le, Project Manager",[22],{"facility":23,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Buck Institute","RECRUITING","Novato","California","94945","United States","US",{"type":31,"coordinates":32},"Point",[33,34],-122.5697,38.10742,{"lat":34,"lon":33},[37,41,42],{"name":38,"role":16,"phone":39,"phoneExt":7,"email":40},"Brianna Stubbs, Research Assistant Profressor, PhD.","4152517451","time-study@buckinstitute.org",{"name":20,"role":16,"phone":7,"phoneExt":7,"email":40},{"name":15,"role":12,"phone":7,"phoneExt":7,"email":7},{"type":44,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[46],{"name":47,"class":48},"Phenome Health","UNKNOWN","100601199","temporal-investigation-of-multimodal-elements-100601199",false,"NCT07107386","Temporal Investigation of Multimodal Elements","An Observational, Longitudinal Study to Characterize the Dynamic Structure of Molecular and Digital Health Data in Healthy Older Adults","TIME","Inclusion Criteria:\n\n* Healthy adults aged 55 years or older.\n* Own a smartphone capable of running study-specific apps.\n* Willing and able to attend in-person visits at the Buck Institute in Novato, CA.\n* Reside in the Pacific or Mountain Time Zones.\n* Able to speak, read, and write English.\n* Willing to wear study devices continuously and allow researchers access to all data.\n* Able to provide informed consent.\n\nExclusion Criteria:\n\n* Hospitalization within the last 3 months.\n* Needing assistance with daily living activities.\n* Working night or irregular shifts.\n* Certain musculoskeletal, pulmonary, or cardiovascular conditions.\n* Uncontrolled high blood pressure (BP \\> 180\u002F100 mmHg).\n* Bleeding disorders, anemia requiring treatment, or recent blood donation.\n* Poor vein access.\n* Unstable health conditions.\n* Chronic antibiotic use.\n* Certain psychiatric disorders.\n* Use of excluded medications, supplements, or products, including certain antibiotics or frequent sleep aids.",true,"ALL","55 Years",{"count":61,"type":62},120,"ESTIMATED","OBSERVATIONAL","The TIME Study is a research project aiming to understand the body's natural rhythms. The goal is to see how daily and weekly changes in our bodies-from what's happening at a molecular level to data from wearable devices-are connected.\n\nWhat is the study about? This study is trying to create a detailed map of how a person's body changes over time. By looking at information from blood, urine, and other samples, as well as data from smartwatches and other devices, researchers want to learn how our bodies' natural cycles work in healthy older adults. The long-term goal is to use this knowledge to help develop more personalized healthcare in the future.\n\nWho can participate? The study is looking for healthy adults, age 55 or older, who have a smartphone and are able to travel to the Buck Institute in Novato, California, for study visits.\n\nParticipants will be asked to:\n\nAttend weekly visits over 11 weeks to provide blood and other samples.\n\nWear health-tracking devices like a smart ring and watch.\n\nUse a smartphone app to answer questions about their daily routines.\n\nComplete two \"challenge\" tests, including drinking a glucose solution and exercising on a stationary bicycle.\n\nReturn for follow-up visits after 6 and 12 months.\n\nAre there any risks or benefits? Benefits: There are no direct health benefits for participants. However, the information gained will help scientists create better diagnostic tools and treatments for future generations.\n\nRisks: The main risks are minor discomfort from things like blood draws or skin irritation from the wearable devices. All personal information and data are kept private and secure.",[66],"Health","2025-08-12",{"date":69,"type":70},"2025-08-15","ACTUAL",{"date":72,"type":70},"2025-06-15",{"date":74,"type":62},"2028-06",{"name":5,"class":6},1]