[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639179":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":18,"responsibleParty":32,"collaborators":18,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":18,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":18,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":56,"whyStopped":18,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":18},{"fullName":5,"class":6},"Suez Canal University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TENS","ACTIVE_COMPARATOR","Maintenance home-based parasacral transcutaneous nerve stimulation and continued urotherapy",[13],"Device: transcutaneous electrical nerve stimulation",{"label":15,"type":16,"description":17,"interventionNames":18},"Observational","NO_INTERVENTION","Observation alone and continued urotherapy",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"DEVICE","transcutaneous electrical nerve stimulation","Parasacral transcutaneous electrical nerve stimulation (parasacral TENS or PTENS) is a non-invasive, neuromodulation intervention used for pediatric overactive bladder (OAB) and neurogenic bladder dysfunction, with emerging evidence for treating nocturnal enuresis.\n\nTarget Area: Posteriorly on the skin at the sacral nerve outflow level (S2-S3), approximately one fingerbreadth away from the midline. Frequency: 10-20 Hz. Pulse Width: 200--700 mus (commonly used to activate sensory nerves). Intensity\u002FAmplitude: Adjusted to the maximum tolerance of the child without causing pain, or just below the motor threshold (avoiding leg muscle contractions). Session 15-60 minutes}\\\\) (20 minutes is common in clinical settings). Frequency of Treatment: 2-3 times per week. Total Duration: Usually a total of 30-40 sessions over 6 months.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":30,"email":31},"Abdelrhman Alshawadfy, Professor","CONTACT","+201091091620","002","abdelrhmanalshawadfy@gmail.com",{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Abdelrhman Alshawadfy","professor","100639179","tens-in-nocturnal-enuresis-100639179",false,"NCT07594353","TENS in Nocturnal Enuresis","Maintenance Parasacral Electrical Nerve Stimulation Versus Observation After Initial Response in Children With Primary Nocturnal Enuresis: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of primary monosymptomatic nocturnal enuresis (PMNE) based on International Children's Continence Society (ICCS) criteria.\n* Persistent symptoms after at least 8 weeks of standardized urotherapy, including counseling on timed voiding, evening fluid management, and bowel optimization.\n* Baseline severity of ≥3 wet nights per week on a 14-night diary.\n* Ability of the child and caregiver to complete diaries and comply with home treatment and follow-up.\n\nExclusion Criteria:\n\n* Non-monosymptomatic enuresis, daytime urgency, daytime incontinence, dysfunctional voiding, or significant post-void residual.\n* Neurogenic bladder, spinal dysraphism, cerebral palsy, epilepsy uncontrolled on treatment, or other neurologic diseases affecting lower urinary tract function.\n* Congenital or acquired urinary tract abnormalities.\n* Active urinary tract infection.\n* Untreated or refractory constipation at enrollment.\n* Implanted electrical devices, significant dermatologic lesions at electrode sites, or other contraindications to electrical stimulation.\n* Cognitive, behavioral, or social circumstances preventing adherence.","ALL","5 Years","16 Years",{"count":47,"type":48},50,"ESTIMATED","INTERVENTIONAL",[51],"NA","Paracascral transcutaneous electrical nerve stimulation (PTENS) is a credible therapeutic option for nocturnal enuresis. The investigators shall investigate whether maintenance PTENS after initial response improves durability of remission compared with observation alone.",[54],"Nocturnal Enuresis in Children",[9],"NOT_YET_RECRUITING","2026-05-22",{"date":59,"type":60},"2026-05-27","ACTUAL",{"date":62,"type":48},"2026-07-01",{"date":64,"type":48},"2027-02-28",{"name":5,"class":6}]