[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100526552":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":24,"locations":34,"responsibleParty":74,"collaborators":76,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":12,"eligibilityCriteria":85,"healthyVolunteers":82,"sex":86,"minAge":87,"maxAge":12,"enrollmentInfo":88,"targetDuration":12,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":101,"overallStatus":58,"whyStopped":12,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":109,"completionDateStruct":111,"leadSponsor":113,"locationsCount":114},{"fullName":5,"class":6},"University of Pennsylvania","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Enhanced Usual Care","NO_INTERVENTION","Patients will undergo baseline interviews with study coordinators. All participants will be screened for malnutrition with the validated malnutrition screening tool (MST). At the baseline interview, patients will receive instructional handouts on dietary changes and recipes as per the updated 2019 European Society for Clinical Nutrition \\& Metabolism (ESPEN) guidelines. Information on the resource CirrhosisCare.ca will also be provided. Participants in the control arm will receive Fitbits to monitor their steps. They will be asked to try and get up to 7000 steps per day, and no follow-up on their progress in terms of step counts will be given during the 12 weeks. All participants will be allowed to keep their Fitbit once they complete the study.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"LiverWatch Intervention","EXPERIMENTAL","Patients will undergo symptom-based monitoring with targeted nutrition support. participants in Arm 2 will also receive educational text messages related to cirrhosis and physical activity. In summary, there are four components to the\n\n* Remote Symptom Monitoring\n* Targeted Nutrition Assessment and Intervention\n* Physical Activity and Rewards Program\n* Motivational Messages\n\nSubjects will be enrolled in an online portal, Way to Health (W2H), which automates many of the research and monitoring functions of the intervention. Patients will receive remote symptom monitoring on a weekly basis, enhanced nutrition assistance through weekly education videos, and \"motivational messages\" on Mondays and Fridays that include education on diet, physical activity, and cirrhosis. Participants in this arm will also be encouraged to increase their step count using a rewards system built through the W2H.",[18],"Behavioral: LiverWatch Intervention",[20],{"type":21,"name":14,"description":22,"armGroupLabels":23,"otherNames":12},"BEHAVIORAL","The LiverWatch Intervention will include standard cirrhosis care and include additional components utilizing the W2H system. Details on this intervention are included in the study arm description.",[14],[25,30],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":29},"Richard Mason, PharmD","CONTACT","215-662-3904","richard.mason@pennmedicine.upenn.edu",{"name":31,"role":27,"phone":32,"phoneExt":12,"email":33},"Marina Serper, MD","215-349-8222","marinas2@pennmedicine.upenn.edu",[35,57],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"University of Michigan","NOT_YET_RECRUITING","Ann Arbor","Michigan","48109","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-83.74088,42.27756,{"lat":47,"lon":46},[50,54],{"name":51,"role":27,"phone":52,"phoneExt":12,"email":53},"Samantha Nikirk, MPH","734-232-4182","samjwalk@med.umich.edu",{"name":55,"role":56,"phone":12,"phoneExt":12,"email":12},"Elliot Tapper, MD","PRINCIPAL_INVESTIGATOR",{"facility":5,"status":58,"city":59,"state":60,"zip":61,"country":41,"countryCode":42,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"RECRUITING","Philadelphia","Pennsylvania","19104",{"type":44,"coordinates":63},[64,65],-75.16362,39.95238,{"lat":65,"lon":64},[68,70,71],{"name":26,"role":27,"phone":28,"phoneExt":12,"email":69},"richard.mason@pennmedicine.edu",{"name":31,"role":56,"phone":12,"phoneExt":12,"email":12},{"name":72,"role":73,"phone":12,"phoneExt":12,"email":12},"Shivan Mehta, MD","SUB_INVESTIGATOR",{"type":75,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[77],{"name":78,"class":79},"Pennsylvania Department of Health","OTHER_GOV","100526552","testing-liverwatch-a-home-based-remote-monitoring-intervention-for-advanced-liver-disease-100526552",false,"NCT06136221","Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease","Inclusion Criteria:\n\n* English speaking\n* Aged 18 years or older\n* Home-dwelling\n* Diagnosis of cirrhosis- Child Turcotte-Pugh (CTP) B or C or a complication in the past 6 months (CTP B or higher, hepatic encephalopathy, variceal bleeding, fluid overload, liver-related hospitalization, or requiring symptom management with diuretics, non-absorbable disaccharides, rifaximin, nonselective beta blockers)\n* Patient and\u002For caregiver is able and willing to receive SMS text messages\n* Willing and able to wear personal fitness trackers and engage with study staff\n\nExclusion Criteria:\n\n* No access to a smartphone\n* Non-home dwelling\n* On hospice care\n* Model for end stage liver disease (MELD) score ≥30\n* Advanced hepatocellular carcinoma, BCLC C or higher\n* Hospitalization within the last 30 days\n* Deemed not appropriate by treating physician for medical reasons\n* Enrolled in other dietary or physical activity interventions\n* Receiving physical therapy as standard of care","ALL","18 Years",{"count":89,"type":90},110,"ESTIMATED","INTERVENTIONAL",[93],"NA","Remote healthcare monitoring for cirrhosis has shown promise in overcoming barriers to accessing specialty care, improving healthcare quality, and reducing mortality. The LiverWatch study is investigating whether a remote nutrition, physical activity, and education intervention can improve health outcomes in those with cirrhosis. In this clinical trial, individuals will be randomized to either enhanced usual care or the LiverWatch intervention. Both groups are given fitbits and asked to increase their step counts. Those in the Liverwatch group will be incentivized for increase their physical activity while also undergoing a personalized nutrition intervention and weekly symptom monitoring and cirrhosis education.",[96,97,98,99,100],"Cirrhosis, Liver","End Stage Liver DIsease","Symptoms and Signs","Physical Inactivity","Muscle Loss",[102,103,104],"Telehealth","Remote Symptom Monitoring","Gamification","2026-05-07",{"date":107,"type":108},"2026-05-11","ACTUAL",{"date":110,"type":108},"2024-05-01",{"date":112,"type":90},"2027-05-31",{"name":5,"class":6},2]